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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011437.1 RefSeqGene
- Range
-
5036..76937
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000698.5 → NP_000689.1 polyunsaturated fatty acid 5-lipoxygenase isoform 1
See identical proteins and their annotated locations for NP_000689.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AW403395, BC132677
- Consensus CDS
-
CCDS7212.1
- UniProtKB/Swiss-Prot
- B7ZLS0, E5FPY5, E5FPY7, E5FPY8, P09917, Q5JQ14
- Related
- ENSP00000363512.2, ENST00000374391.7
- Conserved Domains (2) summary
-
- cd01753
Location:2 → 115
- PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
- cl27717
Location:227 → 665
- Lipoxygenase; Lipoxygenase
-
NM_001256153.3 → NP_001243082.1 polyunsaturated fatty acid 5-lipoxygenase isoform 2
See identical proteins and their annotated locations for NP_001243082.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame segment in the coding region, compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AK225603, AK315223, AW403395, BC132677
- UniProtKB/Swiss-Prot
-
P09917
- Conserved Domains (2) summary
-
- cd01753
Location:2 → 115
- PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
- pfam00305
Location:227 → 633
- Lipoxygenase; Lipoxygenase
-
NM_001256154.3 → NP_001243083.1 polyunsaturated fatty acid 5-lipoxygenase isoform 3
See identical proteins and their annotated locations for NP_001243083.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AW403395, BC143985
- Consensus CDS
-
CCDS58078.1
- UniProtKB/Swiss-Prot
-
P09917
- Related
- ENSP00000437634.1, ENST00000542434.5
- Conserved Domains (2) summary
-
- cd01753
Location:2 → 115
- PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
- pfam00305
Location:227 → 608
- Lipoxygenase; Lipoxygenase
-
NM_001320861.2 → NP_001307790.1 polyunsaturated fatty acid 5-lipoxygenase isoform 4
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
- Source sequence(s)
-
AL731567, AW403395, BC132677
- UniProtKB/Swiss-Prot
-
P09917
- Conserved Domains (2) summary
-
- cd01753
Location:2 → 115
- PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
- pfam00305
Location:227 → 636
- Lipoxygenase; Lipoxygenase
-
NM_001320862.2 → NP_001307791.1 polyunsaturated fatty acid 5-lipoxygenase isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR and initiates translation at a downstream start site compared to variant 1. The encoded isoform (5) has a shorter N-terminus than isoform 1.
- Source sequence(s)
-
AW403395, BC143986
- Conserved Domains (1) summary
-
- pfam00305
Location:82 → 520
- Lipoxygenase; Lipoxygenase