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    SPAG16 sperm associated antigen 16 [ Homo sapiens (human) ]

    Gene ID: 79582, updated on 2-Nov-2024

    Summary

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    Official Symbol
    SPAG16provided by HGNC
    Official Full Name
    sperm associated antigen 16provided by HGNC
    Primary source
    HGNC:HGNC:23225
    See related
    Ensembl:ENSG00000144451 MIM:612173; AllianceGenome:HGNC:23225
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PF20; WDR29
    Summary
    Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 [PubMed 17699735]).[supplied by OMIM, Jul 2008]
    Expression
    Broad expression in testis (RPKM 2.7), thyroid (RPKM 1.2) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See SPAG16 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (213284464..214410501)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (213765296..214894995)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (214149188..215275225)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985981 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:214053177-214054037 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:214052314-214053176 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:214054900-214055760 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17063 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17064 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17065 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17066 Neighboring gene SPAG16 divergent transcript Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:214276253-214277452 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:214552640-214553482 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17067 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17068 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17069 Neighboring gene microRNA 4438 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:214898800-214899778 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:214899779-214900755 Neighboring gene uncharacterized LOC101928084 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:214991690-214992362 Neighboring gene uncharacterized LOC124907973 Neighboring gene ribosomal protein L5 pseudogene 8 Neighboring gene von Willebrand factor C domain containing 2 like Neighboring gene VWC2L intronic transcript 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:215458325-215458965 Neighboring gene endosulfine alpha pseudogene 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Genetic variant in SPAG16 is associated with the susceptibility of ACPA-positive rheumatoid arthritis possibly via regulation of MMP-3. Lin Q, et al. J Orthop Surg Res, 2022 Nov 24. PMID 36434627, Free PMC Article
    2. Isolation and expression of the human hPF20 gene orthologous to Chlamydomonas PF20: evaluation as a candidate for axonemal defects of respiratory cilia and sperm flagella. Pennarun G, et al. Am J Respir Cell Mol Biol, 2002 Mar. PMID 11867345
    3. Genetic variation in SPAG16 regions encoding the WD40 repeats is not associated with reduced sperm motility and axonemal defects in a population of infertile males. Nagarkatti-Gude DR, et al. BMC Urol, 2012 Sep 10. PMID 22963137, Free PMC Article
    4. Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis. Knevel R, et al. Ann Rheum Dis, 2014 Nov. PMID 23956247, Free PMC Article
    5. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. de Bock L, et al. J Immunol, 2014 Sep 1. PMID 25086173

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Genetic variant in SPAG16 is associated with the susceptibility of ACPA-positive rheumatoid arthritis possibly via regulation of MMP-3.
      Title: Genetic variant in SPAG16 is associated with the susceptibility of ACPA-positive rheumatoid arthritis possibly via regulation of MMP-3.
    2. Identification and Classification of Novel Genetic Variants: En Route to the Diagnosis of Primary Ciliary Dyskinesia.
      Title: Identification and Classification of Novel Genetic Variants: En Route to the Diagnosis of Primary Ciliary Dyskinesia.
    3. Short-SOX5 regulates transcription of human SPAG16L gene via directly binding to the promoter of SPAG16L.
      Title: Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5.
    4. SPAG16 is a novel autoantibody target in a subgroup of MS patients and in combination with other diagnostic criteria, elevated levels of anti-SPAG16 Abs could be used as a biomarker for diagnosis.
      Title: Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis.
    5. SPAG16 influences MMP-3 regulation and protects against joint destruction in autoantibody-positive rheumatoid arthritis.
      Title: Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis.
    6. Analysis of SPAG16 regions encoding conserved WD repeats revealed no evidence for association of mutations or genetic variation with sperm motility in infertile males.
      Title: Genetic variation in SPAG16 regions encoding the WD40 repeats is not associated with reduced sperm motility and axonemal defects in a population of infertile males.
    7. Observational study of gene-disease association. (HuGE Navigator)
      Title: Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.
    8. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    9. Heterozygous mutation that affects both SPAG16L and SPAG16S does not cause male infertility in man, but is associated with reduced stability of the interacting proteins of the central apparatus.
      Title: A heterozygous mutation disrupting the SPAG16 gene results in biochemical instability of central apparatus components of the human sperm axoneme.
    10. Data describe the cloning of human and mouse Pf20 proteins that interact with Spag6 protein.
      Title: A sperm-associated WD repeat protein orthologous to Chlamydomonas PF20 associates with Spag6, the mammalian orthologue of Chlamydomonas PF16.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog
    Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Replication interactions

    Interaction Pubs
    Knockdown of sperm associated antigen 16 (SPAG16) by siRNA enhances the early stages of HIV-1 replication in HeLa-CD4 cells infected with viral pseudotypes HIV89.6R and HIV8.2N PubMed

    Go to the HIV-1, Human Interaction Database

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ22724, FLJ37717, MGC87036, DKFZp666P1710

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axoneme assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in axoneme assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cerebrospinal fluid circulation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in mucociliary clearance IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sperm axoneme assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axonemal central apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in axoneme ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in sperm flagellum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sperm-associated antigen 16 protein
    Names
    WD repeat domain 29
    pf20 protein homolog
    sperm-associated WD repeat protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025436.3 → NP_001020607.1  sperm-associated antigen 16 protein isoform 2

      See identical proteins and their annotated locations for NP_001020607.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and lacks a large portion of the 3' coding region, compared to variant 1. The encoded isoform (2) is significantly shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      BC067756, CA313710
      Consensus CDS
      CCDS46508.1
      UniProtKB/Swiss-Prot
      Q8N0X2
      UniProtKB/TrEMBL
      Q4G1A2
      Related
      ENSP00000415079.2, ENST00000432529.6

    2. NM_024532.5 → NP_078808.3  sperm-associated antigen 16 protein isoform 1

      See identical proteins and their annotated locations for NP_078808.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AF310672, AF490390, AK302351
      Consensus CDS
      CCDS2396.1
      UniProtKB/Swiss-Prot
      Q498B7, Q658W1, Q68DB3, Q6I9Z6, Q8N0X2, Q8N9C7, Q9H601
      UniProtKB/TrEMBL
      Q4G1A2
      Related
      ENSP00000332592.5, ENST00000331683.10
      Conserved Domains (4) summary
      COG2319
      Location:341 → 631
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:344 → 631
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:355 → 392
      7WD40; WD40 repeat [structural motif]
      cl09111
      Location:160 → 271
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    RNA

    1. NR_047659.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has multiple differences, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK302351, AW207406, BC025379
      Related
      ENST00000406979.6

    2. NR_047660.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an internal exon in the 5' region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK302351, BC025379

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      213284464..214410501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011511814.2 → XP_011510116.1  sperm-associated antigen 16 protein isoform X1

      UniProtKB/TrEMBL
      Q4G1A2
      Conserved Domains (4) summary
      COG2319
      Location:310 → 600
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:313 → 600
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:324 → 361
      7WD40; WD40 repeat [structural motif]
      cl09111
      Location:129 → 240
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    2. XM_011511820.3 → XP_011510122.1  sperm-associated antigen 16 protein isoform X7

      Conserved Domains (4) summary
      COG2319
      Location:302 → 569
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:344 → 569
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:355 → 392
      7WD40; WD40 repeat [structural motif]
      cl09111
      Location:160 → 271
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    3. XM_011511815.3 → XP_011510117.1  sperm-associated antigen 16 protein isoform X2

      Conserved Domains (4) summary
      COG2319
      Location:342 → 577
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:348 → 580
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:356 → 392
      7WD40; WD40 repeat [structural motif]
      cl09111
      Location:160 → 271
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    4. XM_011511817.3 → XP_011510119.1  sperm-associated antigen 16 protein isoform X4

      Conserved Domains (3) summary
      COG2319
      Location:341 → 561
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:348 → 551
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:356 → 392
      7WD40; WD40 repeat [structural motif]

    5. XM_011511816.4 → XP_011510118.1  sperm-associated antigen 16 protein isoform X3

      Conserved Domains (4) summary
      COG2319
      Location:343 → 585
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:348 → 551
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:356 → 392
      7WD40; WD40 repeat [structural motif]
      cl09111
      Location:160 → 271
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    6. XM_011511818.3 → XP_011510120.1  sperm-associated antigen 16 protein isoform X6

      Conserved Domains (4) summary
      COG2319
      Location:341 → 561
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:348 → 551
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:356 → 392
      7WD40; WD40 repeat [structural motif]
      cl09111
      Location:160 → 271
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    7. XM_011511824.3 → XP_011510126.1  sperm-associated antigen 16 protein isoform X9

      Conserved Domains (3) summary
      COG2319
      Location:341 → 516
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:348 → 518
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:356 → 392
      7WD40; WD40 repeat [structural motif]

    8. XM_011511831.3 → XP_011510133.1  sperm-associated antigen 16 protein isoform X15

      See identical proteins and their annotated locations for XP_011510133.1

      UniProtKB/TrEMBL
      E7EWV3

    9. XM_011511832.3 → XP_011510134.1  sperm-associated antigen 16 protein isoform X16

      See identical proteins and their annotated locations for XP_011510134.1

      UniProtKB/TrEMBL
      E7EWV3

    10. XM_011511828.3 → XP_011510130.1  sperm-associated antigen 16 protein isoform X13

      UniProtKB/TrEMBL
      E7EWV3

    11. XM_011511829.3 → XP_011510131.1  sperm-associated antigen 16 protein isoform X14

      UniProtKB/TrEMBL
      E7EWV3

    12. XM_011511827.3 → XP_011510129.1  sperm-associated antigen 16 protein isoform X12

      UniProtKB/TrEMBL
      E7EWV3

    13. XM_011511837.4 → XP_011510139.1  sperm-associated antigen 16 protein isoform X20

      UniProtKB/TrEMBL
      E7EWV3

    14. XM_006712746.4 → XP_006712809.1  sperm-associated antigen 16 protein isoform X18

      UniProtKB/TrEMBL
      E7EWV3
      Related
      ENSP00000400847.1, ENST00000447990.1

    15. XM_017004899.3 → XP_016860388.1  sperm-associated antigen 16 protein isoform X17

    16. XM_011511823.4 → XP_011510125.1  sperm-associated antigen 16 protein isoform X8

      See identical proteins and their annotated locations for XP_011510125.1

      UniProtKB/TrEMBL
      B4DYB5, C9JV44
      Conserved Domains (2) summary
      cd00200
      Location:241 → 528
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:252 → 289
      7WD40; WD40 repeat [structural motif]

    17. XM_011511819.3 → XP_011510121.1  sperm-associated antigen 16 protein isoform X5

      UniProtKB/TrEMBL
      Q4G1A2
      Conserved Domains (4) summary
      COG2319
      Location:287 → 577
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:290 → 577
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:301 → 338
      7WD40; WD40 repeat [structural motif]
      cl09111
      Location:106 → 217
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    18. XM_047445817.1 → XP_047301773.1  sperm-associated antigen 16 protein isoform X10

    19. XM_017004897.1 → XP_016860386.1  sperm-associated antigen 16 protein isoform X10

      UniProtKB/TrEMBL
      B4DYB5, C9JV44
      Conserved Domains (4) summary
      COG2319
      Location:222 → 512
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:225 → 512
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:236 → 273
      7WD40; WD40 repeat [structural motif]
      cl09111
      Location:41 → 152
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    20. XM_017004898.1 → XP_016860387.1  sperm-associated antigen 16 protein isoform X11

    21. XM_024453140.2 → XP_024308908.1  sperm-associated antigen 16 protein isoform X19

      Conserved Domains (2) summary
      cd00200
      Location:38 → 325
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:49 → 86
      7WD40; WD40 repeat [structural motif]

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      213765296..214894995
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054343872.1 → XP_054199847.1  sperm-associated antigen 16 protein isoform X1

    2. XM_054343878.1 → XP_054199853.1  sperm-associated antigen 16 protein isoform X7

    3. XM_054343873.1 → XP_054199848.1  sperm-associated antigen 16 protein isoform X2

    4. XM_054343875.1 → XP_054199850.1  sperm-associated antigen 16 protein isoform X4

    5. XM_054343874.1 → XP_054199849.1  sperm-associated antigen 16 protein isoform X3

    6. XM_054343877.1 → XP_054199852.1  sperm-associated antigen 16 protein isoform X6

    7. XM_054343880.1 → XP_054199855.1  sperm-associated antigen 16 protein isoform X9

    8. XM_054343882.1 → XP_054199857.1  sperm-associated antigen 16 protein isoform X21

    9. XM_054343887.1 → XP_054199862.1  sperm-associated antigen 16 protein isoform X15

    10. XM_054343888.1 → XP_054199863.1  sperm-associated antigen 16 protein isoform X16

    11. XM_054343885.1 → XP_054199860.1  sperm-associated antigen 16 protein isoform X13

    12. XM_054343886.1 → XP_054199861.1  sperm-associated antigen 16 protein isoform X14

    13. XM_054343884.1 → XP_054199859.1  sperm-associated antigen 16 protein isoform X12

    14. XM_054343892.1 → XP_054199867.1  sperm-associated antigen 16 protein isoform X20

    15. XM_054343890.1 → XP_054199865.1  sperm-associated antigen 16 protein isoform X18

    16. XM_054343889.1 → XP_054199864.1  sperm-associated antigen 16 protein isoform X17

    17. XM_054343879.1 → XP_054199854.1  sperm-associated antigen 16 protein isoform X8

    18. XM_054343876.1 → XP_054199851.1  sperm-associated antigen 16 protein isoform X5

    19. XM_054343881.1 → XP_054199856.1  sperm-associated antigen 16 protein isoform X10

    20. XM_054343883.1 → XP_054199858.1  sperm-associated antigen 16 protein isoform X11

    21. XM_054343891.1 → XP_054199866.1  sperm-associated antigen 16 protein isoform X19

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8N0X2.2 GenPept UniProtKB/Swiss-Prot:Q8N0X2

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