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    RNF32 ring finger protein 32 [ Homo sapiens (human) ]

    Gene ID: 140545, updated on 28-Oct-2024

    Summary

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    Official Symbol
    RNF32provided by HGNC
    Official Full Name
    ring finger protein 32provided by HGNC
    Primary source
    HGNC:HGNC:17118
    See related
    Ensembl:ENSG00000105982 MIM:610241; AllianceGenome:HGNC:17118
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSD15; LMBR2; FKSG33
    Summary
    The protein encoded by this gene contains two RING ring finger motifs. RING finger motifs are present in a variety of functionally distinct proteins and are known to be involved in protein-DNA or protein-protein interactions. This gene was found to be expressed during spermatogenesis, most likely in spermatocytes and/or in spermatids. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
    Expression
    Biased expression in testis (RPKM 12.4), bone marrow (RPKM 0.9) and 4 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See RNF32 in Genome Data Viewer
    Location:
    7q36.3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (156640204..156677130)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (157827918..157864843)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (156433468..156469824)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene RNF32 divergent transcript Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:156332839-156333338 Neighboring gene long intergenic non-protein coding RNA 244 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:156377606-156378120 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:156378121-156378635 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:156400279-156400790 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26907 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26908 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:156412155-156412844 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr7:156412845-156413534 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:156432899-156433490 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:156443773-156443992 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26909 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26910 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:156449836-156451035 Neighboring gene ribosomal protein L26 pseudogene 23 Neighboring gene RNF32 antisense RNA 1 Neighboring gene limb development membrane protein 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26911 Neighboring gene Sharpr-MPRA regulatory region 13578 Neighboring gene ZRS shadow enhancer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26912 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26913 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:156613382-156613882 Neighboring gene ZPA regulatory sequence Neighboring gene ReSE screen-validated silencer GRCh37_chr7:156647348-156647581 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:156657413-156657607 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:156665750-156665992 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:156670519-156670739 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18852 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18853 Neighboring gene uncharacterized LOC102723795 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26914 Neighboring gene RNA, U4 small nuclear 31, pseudogene Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:156707384-156708583 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26915 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26916 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26917

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. RING finger proteins are involved in the progression of barrett esophagus to esophageal adenocarcinoma: a preliminary study. Wang XW, et al. Gut Liver, 2014 Sep. PMID 25228972, Free PMC Article
    2. Mutation analysis of a large Chinese pedigree with congenital preaxial polydactyly. Li H, et al. Eur J Hum Genet, 2009 May. PMID 19066618, Free PMC Article
    3. High incidence of t(7;12)(q36;p13) in infant AML but not in infant ALL, with a dismal outcome and ectopic expression of HLXB9. von Bergh AR, et al. Genes Chromosomes Cancer, 2006 Aug. PMID 16646086
    4. A single C to T transition in intron 5 of LMBR1 gene is associated with triphalangeal thumb-polysyndactyly syndrome in a Chinese family. Wang ZQ, et al. Biochem Biophys Res Commun, 2007 Apr 6. PMID 17300748
    5. A double RING-H2 domain in RNF32, a gene expressed during sperm formation. van Baren MJ, et al. Biochem Biophys Res Commun, 2002 Mar 22. PMID 11890671

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. molecular cloning of a RING domain protein expressed during sperm formation
      Title: A double RING-H2 domain in RNF32, a gene expressed during sperm formation.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2021-02-02)

    ClinGen Genome Curation Page
    Haploinsufficency

    Dosage sensitivity unlikely (Last evaluated 2021-02-02)

    ClinGen Genome Curation PagePubMed

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in aggresome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nuclear body IDA
    Inferred from Direct Assay
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 32

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001184996.2 → NP_001171925.1  RING finger protein 32 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1, 2 and 3 all encode isoform a.
      Source sequence(s)
      AK314067, AL136874
      Consensus CDS
      CCDS5944.1
      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Related
      ENSP00000405588.2, ENST00000432459.6
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    2. NM_001184997.1 → NP_001171926.1  RING finger protein 32 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode isoform a.
      Source sequence(s)
      AA412402, AF325690, AF441222
      Consensus CDS
      CCDS5944.1
      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Related
      ENSP00000376499.2, ENST00000392743.6
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    3. NM_001308273.2 → NP_001295202.1  RING finger protein 32 isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and uses an alternate splice site in the 3' terminal exon, resulting in an alternate 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.
      Source sequence(s)
      AL136874, BC028120, DB198291
      Consensus CDS
      CCDS78293.1
      UniProtKB/TrEMBL
      G5E940
      Related
      ENSP00000308894.8, ENST00000311822.12
      Conserved Domains (2) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif

    4. NM_001308274.1 → NP_001295203.1  RING finger protein 32 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and contains alternate 3' exon structure, resulting in an alternate 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) has a distinct C-terminus and is shorter than isoform a.
      Source sequence(s)
      BC015416
      Consensus CDS
      CCDS78292.1
      UniProtKB/TrEMBL
      E9PES2
      Related
      ENSP00000376497.2, ENST00000392741.6
      Conserved Domains (2) summary
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      cd16677
      Location:126 → 169
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins

    5. NM_030936.4 → NP_112198.1  RING finger protein 32 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 all encode isoform a.
      Source sequence(s)
      AL136874, BI460257, DB445126
      Consensus CDS
      CCDS5944.1
      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Related
      ENSP00000315950.5, ENST00000317955.10
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    RNA

    1. NR_131778.1 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) contains an additional internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AF441224, AL136874
      Related
      ENST00000392747.6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      156640204..156677130
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024446666.2 → XP_024302434.1  RING finger protein 32 isoform X4

      UniProtKB/TrEMBL
      E9PES2
      Related
      ENSP00000385815.2, ENST00000404282.6
      Conserved Domains (2) summary
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      cd16677
      Location:126 → 169
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins

    2. XM_011515811.3 → XP_011514113.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    3. XM_047419904.1 → XP_047275860.1  RING finger protein 32 isoform X4

    4. XM_011515810.3 → XP_011514112.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    5. XM_047419894.1 → XP_047275850.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    6. XM_011515808.4 → XP_011514110.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    7. XM_011515809.4 → XP_011514111.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    8. XM_047419899.1 → XP_047275855.1  RING finger protein 32 isoform X3

      UniProtKB/TrEMBL
      G5E940

    9. XM_011515805.4 → XP_011514107.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Related
      ENSP00000385285.1, ENST00000405335.5
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    10. XM_047419898.1 → XP_047275854.1  RING finger protein 32 isoform X2

    11. XM_047419895.1 → XP_047275851.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    12. XM_011515806.4 → XP_011514108.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    13. XM_011515812.4 → XP_011514114.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    14. XM_011515804.4 → XP_011514106.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    15. XM_011515813.3 → XP_011514115.1  RING finger protein 32 isoform X2

      Conserved Domains (2) summary
      pfam00612
      Location:175 → 194
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:278 → 339
      zf-RING_2; Ring finger domain

    16. XM_047419900.1 → XP_047275856.1  RING finger protein 32 isoform X4

    17. XM_047419901.1 → XP_047275857.1  RING finger protein 32 isoform X4

    18. XM_047419902.1 → XP_047275858.1  RING finger protein 32 isoform X4

    19. XM_017011755.2 → XP_016867244.1  RING finger protein 32 isoform X4

      UniProtKB/TrEMBL
      E9PES2
      Conserved Domains (2) summary
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      cd16677
      Location:126 → 169
      RING1-H2_RNF32; RING finger 1, H2 subclass, found in RING finger protein 32 (RNF32) and similar proteins

    20. XM_047419905.1 → XP_047275861.1  RING finger protein 32 isoform X5

    21. XM_005249522.6 → XP_005249579.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    22. XM_047419903.1 → XP_047275859.1  RING finger protein 32 isoform X4

    23. XM_047419897.1 → XP_047275853.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    24. XM_047419896.1 → XP_047275852.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    25. XM_011515807.4 → XP_011514109.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1
      Conserved Domains (3) summary
      cd00162
      Location:127 → 171
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      pfam00612
      Location:188 → 207
      IQ; IQ calmodulin-binding motif
      pfam13639
      Location:291 → 352
      zf-RING_2; Ring finger domain

    RNA

    1. XR_007059986.1 RNA Sequence

    2. XR_007059985.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      157827918..157864843
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054357289.1 → XP_054213264.1  RING finger protein 32 isoform X4

    2. XM_054357270.1 → XP_054213245.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    3. XM_054357288.1 → XP_054213263.1  RING finger protein 32 isoform X4

    4. XM_054357277.1 → XP_054213252.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    5. XM_054357278.1 → XP_054213253.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    6. XM_054357274.1 → XP_054213249.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    7. XM_054357271.1 → XP_054213246.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    8. XM_054357281.1 → XP_054213256.1  RING finger protein 32 isoform X2

    9. XM_054357273.1 → XP_054213248.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    10. XM_054357268.1 → XP_054213243.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    11. XM_054357269.1 → XP_054213244.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    12. XM_054357280.1 → XP_054213255.1  RING finger protein 32 isoform X2

    13. XM_054357284.1 → XP_054213259.1  RING finger protein 32 isoform X4

    14. XM_054357285.1 → XP_054213260.1  RING finger protein 32 isoform X4

    15. XM_054357286.1 → XP_054213261.1  RING finger protein 32 isoform X4

    16. XM_054357283.1 → XP_054213258.1  RING finger protein 32 isoform X4

    17. XM_054357275.1 → XP_054213250.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    18. XM_054357272.1 → XP_054213247.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    19. XM_054357279.1 → XP_054213254.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    20. XM_054357287.1 → XP_054213262.1  RING finger protein 32 isoform X4

    21. XM_054357276.1 → XP_054213251.1  RING finger protein 32 isoform X1

      UniProtKB/Swiss-Prot
      Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9H0A6, Q9Y6U1

    22. XM_054357282.1 → XP_054213257.1  RING finger protein 32 isoform X3

      UniProtKB/TrEMBL
      G5E940

    23. XM_054357290.1 → XP_054213265.1  RING finger protein 32 isoform X5

    RNA

    1. XR_008487530.1 RNA Sequence

    2. XR_008487529.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9H0A6.1 GenPept UniProtKB/Swiss-Prot:Q9H0A6

    Gene LinkOut

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