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    IMPDH1 inosine monophosphate dehydrogenase 1 [ Homo sapiens (human) ]

    Gene ID: 3614, updated on 28-Oct-2024

    Summary

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    Official Symbol
    IMPDH1provided by HGNC
    Official Full Name
    inosine monophosphate dehydrogenase 1provided by HGNC
    Primary source
    HGNC:HGNC:6052
    See related
    Ensembl:ENSG00000106348 MIM:146690; AllianceGenome:HGNC:6052
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IMPD; RP10; IMPD1; LCA11; IMPDH-I; sWSS2608
    Summary
    The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
    Expression
    Ubiquitous expression in fat (RPKM 19.1), appendix (RPKM 15.8) and 24 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See IMPDH1 in Genome Data Viewer
    Location:
    7q32.1
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (128392277..128409982, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (129704030..129721735, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (128032331..128050036, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26597 Neighboring gene RNA, U7 small nuclear 27 pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:127999072-127999941 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:127999942-128000810 Neighboring gene proline rich transmembrane protein 4 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:128000811-128001679 Neighboring gene uncharacterized LOC107986845 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:128031425-128031926 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:128043787-128044403 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:128044404-128045019 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:128045637-128046251 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18605 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18606 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26598 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18607 Neighboring gene ribosomal protein L37 pseudogene 16 Neighboring gene RNA, U7 small nuclear 54 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Spectrum and frequency of mutations in IMPDH1 associated with autosomal dominant retinitis pigmentosa and leber congenital amaurosis. Bowne SJ, et al. Invest Ophthalmol Vis Sci, 2006 Jan. PMID 16384941, Free PMC Article
    2. IMP dehydrogenase rod/ring structures in acral melanomas. Keppeke GD, et al. Pigment Cell Melanoma Res, 2020 May. PMID 31883196
    3. Malnutrition Risk in Kidney Recipients Treated With Mycophenolate Mofetil Is Associated With IMPDH1 rs2278294 Polymorphism. Pazik J, et al. Transplant Proc, 2018 Jul-Aug. PMID 30056902
    4. Phenotypic variability associated with the D226N allele of IMPDH1. Ali S, et al. Ophthalmology, 2015 Feb. PMID 25439607
    5. Mutation analysis of pre-mRNA splicing genes in Chinese families with retinitis pigmentosa. Pan X, et al. Mol Vis, 2014. PMID 24940031, Free PMC Article

    See all (102) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Impact of Terminal Peptide Extensions of Retinal Inosine 5 Monophosphate Dehydrogenase 1 Isoforms on their DNA-binding Activities.
      Title: The Impact of Terminal Peptide Extensions of Retinal Inosine 5´Monophosphate Dehydrogenase 1 Isoforms on their DNA-binding Activities.
    2. Datasets-Based IMPDH1 Revisited: Heterozygous Missense Variants for Dominant Retinitis Pigmentosa While Truncation Variants Are Likely Non-Pathogenic.
      Title: Datasets-Based IMPDH1 Revisited: Heterozygous Missense Variants for Dominant Retinitis Pigmentosa While Truncation Variants Are Likely Non-Pathogenic.
    3. IMPDH1-associated autosomal dominant retinitis pigmentosa: natural history of novel variant Lys314Gln and a comprehensive literature search.
      Title: IMPDH1-associated autosomal dominant retinitis pigmentosa: natural history of novel variant Lys314Gln and a comprehensive literature search.
    4. c-Myc-IMPDH1/2 axis promotes tumourigenesis by regulating GTP metabolic reprogramming.
      Title: c-Myc-IMPDH1/2 axis promotes tumourigenesis by regulating GTP metabolic reprogramming.
    5. IMPDH1, a prognostic biomarker and immunotherapy target that correlates with tumor immune microenvironment in pan-cancer and hepatocellular carcinoma.
      Title: IMPDH1, a prognostic biomarker and immunotherapy target that correlates with tumor immune microenvironment in pan-cancer and hepatocellular carcinoma.
    6. MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells.
      Title: MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells.
    7. Inosine monophosphate dehydrogenase type1 sustains tumor growth in hepatocellular carcinoma.
      Title: Inosine monophosphate dehydrogenase type1 sustains tumor growth in hepatocellular carcinoma.
    8. Inosine 5'-Monophosphate Dehydrogenase Cytoophidia Neighbor Insulin Granules in Pancreatic beta Cells.
      Title: Inosine 5'-Monophosphate Dehydrogenase Cytoophidia Neighbor Insulin Granules in Pancreatic β Cells.
    9. IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
      Title: IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
    10. Disease Progression in Patients with Autosomal Dominant Retinitis Pigmentosa due to a Mutation in Inosine Monophosphate Dehydrogenase 1 (IMPDH1).
      Title: Disease Progression in Patients with Autosomal Dominant Retinitis Pigmentosa due to a Mutation in Inosine Monophosphate Dehydrogenase 1 (IMPDH1).
    Submit: New GeneRIF Correction See all GeneRIFs (43)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp781N0678

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables IMP dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in GMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in GTP biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in azurophil granule lumen TAS
    Traceable Author Statement
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in extracellular region TAS
    Traceable Author Statement
    more info
    		  
    located_in ficolin-1-rich granule lumen TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in secretory granule lumen TAS
    Traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    inosine-5'-monophosphate dehydrogenase 1
    Names
    IMP (inosine 5'-monophosphate) dehydrogenase 1
    IMP (inosine monophosphate) dehydrogenase 1
    IMPD 1
    IMPDH 1
    NP_000874.2
    NP_001096075.1
    NP_001136045.1
    NP_001136046.1
    NP_001136047.1
    NP_001136048.1
    NP_001291450.1
    NP_899066.1
    XP_016867662.1
    XP_024302523.1
    XP_024302524.1
    XP_024302525.1
    XP_024302526.1
    XP_047276289.1
    XP_047276290.1
    XP_054214122.1
    XP_054214123.1
    XP_054214124.1
    XP_054214125.1
    XP_054214126.1
    XP_054214127.1
    XP_054214128.1
    XP_054214129.1
    XP_054214130.1
    XP_054214131.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_009194.1 RefSeqGene

      Range
      5001..22706
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_000883.4 → NP_000874.2  inosine-5'-monophosphate dehydrogenase 1 isoform a

      See identical proteins and their annotated locations for NP_000874.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AK092452, AK122994, CD014010, DA566139, DC326380
      Consensus CDS
      CCDS34749.1
      UniProtKB/TrEMBL
      Q5H9Q6
      Related
      ENSP00000345096.6, ENST00000338791.11
      Conserved Domains (3) summary
      cd00381
      Location:114 → 578
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
      cd04602
      Location:200 → 315
      CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
      PTZ00314
      Location:99 → 595
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    2. NM_001102605.2 → NP_001096075.1  inosine-5'-monophosphate dehydrogenase 1 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AK122994, BC033622, CD014010, DA566139
      Consensus CDS
      CCDS43643.1
      UniProtKB/TrEMBL
      Q5H9Q6
      Related
      ENSP00000346219.5, ENST00000354269.9
      Conserved Domains (3) summary
      cd00381
      Location:104 → 568
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
      cd04602
      Location:190 → 305
      CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
      PTZ00314
      Location:89 → 585
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    3. NM_001142573.2 → NP_001136045.1  inosine-5'-monophosphate dehydrogenase 1 isoform e

      See identical proteins and their annotated locations for NP_001136045.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (e) is shorter at the N-terminus compared to isoform a.
      Source sequence(s)
      AC010655, AK122994, CD014008, DC299597
      UniProtKB/Swiss-Prot
      A4D0Z6, A4D0Z7, A6NDW5, A6NNI6, B3KNP7, B3KVM8, B4DE09, C9JV30, J3KNX8, P20839, Q8N194, Q96NU2
      UniProtKB/TrEMBL
      C9J381
      Related
      ENSP00000417296.1, ENST00000470772.5
      Conserved Domains (3) summary
      cd00381
      Location:29 → 493
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
      cd04602
      Location:115 → 230
      CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
      PTZ00314
      Location:14 → 510
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    4. NM_001142574.2 → NP_001136046.1  inosine-5'-monophosphate dehydrogenase 1 isoform f

      See identical proteins and their annotated locations for NP_001136046.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence and lacks an alternate in-frame segment compared to variant 1. The resulting isoform (f) is shorter at the N-terminus and lacks an internal segment compared to isoform a.
      Source sequence(s)
      AC010655, AK122994, AK293413, CD014008, DC299597
      Consensus CDS
      CCDS55161.1
      UniProtKB/TrEMBL
      C9J381
      Related
      ENSP00000420185.1, ENST00000480861.5
      Conserved Domains (3) summary
      cd00381
      Location:29 → 488
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
      cd04602
      Location:110 → 225
      CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
      PTZ00314
      Location:14 → 505
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    5. NM_001142575.2 → NP_001136047.1  inosine-5'-monophosphate dehydrogenase 1 isoform g

      See identical proteins and their annotated locations for NP_001136047.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (g) is shorter at the N-terminus and lacks an internal segment compared to isoform a.
      Source sequence(s)
      AC010655, AK054640, AK122994, CD014008, DC299597
      Consensus CDS
      CCDS47700.1
      UniProtKB/TrEMBL
      C9J381
      Related
      ENSP00000420803.1, ENST00000496200.5
      Conserved Domains (3) summary
      smart00116
      Location:159 → 206
      CBS; Domain in cystathionine beta-synthase and other proteins
      cd00381
      Location:29 → 468
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
      PTZ00314
      Location:14 → 485
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    6. NM_001142576.2 → NP_001136048.1  inosine-5'-monophosphate dehydrogenase 1 isoform d

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (dz) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AC010655, CD014008, DA980797
      Consensus CDS
      CCDS47699.1
      UniProtKB/TrEMBL
      Q6ZNB1
      Related
      ENSP00000399400.2, ENST00000419067.6
      Conserved Domains (3) summary
      cd00381
      Location:86 → 545
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
      cd04602
      Location:167 → 282
      CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
      PTZ00314
      Location:86 → 562
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    7. NM_001304521.2 → NP_001291450.1  inosine-5'-monophosphate dehydrogenase 1 isoform h

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) lacks three consecutive in-frame exons in the 5' coding region, compared to variant 1. The encoded isoform (h) is shorter compared to isoform a.
      Source sequence(s)
      AK054667, AK122994, AK131294, BX406207, CD014008
      UniProtKB/TrEMBL
      Q6ZNB1
      Conserved Domains (3) summary
      cd00381
      Location:50 → 509
      IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
      cd04602
      Location:131 → 246
      CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
      PTZ00314
      Location:50 → 526
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    8. NM_183243.3 → NP_899066.1  inosine-5'-monophosphate dehydrogenase 1 isoform b

      See identical proteins and their annotated locations for NP_899066.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AK122994, BC033622, CD014010
      Consensus CDS
      CCDS34748.1
      UniProtKB/TrEMBL
      Q6ZNB1
      Related
      ENSP00000265385.8, ENST00000348127.11
      Conserved Domains (1) summary
      PTZ00314
      Location:63 → 559
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      128392277..128409982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024446757.2 → XP_024302525.1  inosine-5'-monophosphate dehydrogenase 1 isoform X3

      UniProtKB/TrEMBL
      Q6ZNB1
      Related
      ENSP00000496892.1, ENST00000648462.1
      Conserved Domains (1) summary
      PTZ00314
      Location:50 → 526
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    2. XM_024446756.1 → XP_024302524.1  inosine-5'-monophosphate dehydrogenase 1 isoform X2

      UniProtKB/TrEMBL
      Q6ZNB1
      Conserved Domains (1) summary
      PTZ00314
      Location:63 → 559
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    3. XM_024446755.1 → XP_024302523.1  inosine-5'-monophosphate dehydrogenase 1 isoform X1

      UniProtKB/TrEMBL
      Q5H9Q6
      Conserved Domains (1) summary
      PTZ00314
      Location:89 → 585
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    4. XM_024446758.1 → XP_024302526.1  inosine-5'-monophosphate dehydrogenase 1 isoform X4

      UniProtKB/TrEMBL
      B3KRZ3
      Conserved Domains (1) summary
      PTZ00314
      Location:22 → 518
      PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

    5. XM_047420334.1 → XP_047276290.1  inosine-5'-monophosphate dehydrogenase 1 isoform X6

    6. XM_047420333.1 → XP_047276289.1  inosine-5'-monophosphate dehydrogenase 1 isoform X5

    7. XM_017012173.1 → XP_016867662.1  inosine-5'-monophosphate dehydrogenase 1 isoform X7

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      129704030..129721735 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054358152.1 → XP_054214127.1  inosine-5'-monophosphate dehydrogenase 1 isoform X3

    2. XM_054358151.1 → XP_054214126.1  inosine-5'-monophosphate dehydrogenase 1 isoform X2

    3. XM_054358148.1 → XP_054214123.1  inosine-5'-monophosphate dehydrogenase 1 isoform X9

    4. XM_054358150.1 → XP_054214125.1  inosine-5'-monophosphate dehydrogenase 1 isoform X1

    5. XM_054358149.1 → XP_054214124.1  inosine-5'-monophosphate dehydrogenase 1 isoform X10

    6. XM_054358147.1 → XP_054214122.1  inosine-5'-monophosphate dehydrogenase 1 isoform X8

    7. XM_054358153.1 → XP_054214128.1  inosine-5'-monophosphate dehydrogenase 1 isoform X4

    8. XM_054358156.1 → XP_054214131.1  inosine-5'-monophosphate dehydrogenase 1 isoform X6

    9. XM_054358155.1 → XP_054214130.1  inosine-5'-monophosphate dehydrogenase 1 isoform X5

    10. XM_054358154.1 → XP_054214129.1  inosine-5'-monophosphate dehydrogenase 1 isoform X11

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P20839.2 GenPept UniProtKB/Swiss-Prot:P20839

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