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    htt-1 HunTingTin gene family member;Serine/threonine-protein kinase TOR [ Caenorhabditis elegans ]

    Gene ID: 181204, updated on 2-Nov-2024

    Summary

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    Official Symbol
    htt-1
    Official Full Name
    HunTingTin gene family member;Serine/threonine-protein kinase TOR
    Primary source
    WormBase:WBGene00009027
    Locus tag
    CELE_F21G4.6
    See related
    AllianceGenome:WB:WBGene00009027
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable kinase activity. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Huntington's disease and Parkinson's disease. Orthologous to human HTT (huntingtin). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See htt-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    28
    Sequence:
    Chromosome: X; NC_003284.9 (9908794..9917448, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene PHD-type domain-containing protein Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein Neighboring gene FOLate Receptor homolog Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    HunTingTin gene family member;Serine/threonine-protein kinase TOR
    NP_001417862.1
    • Product from WormBase gene class htt;
      Confirmed by transcript evidence
    NP_001417863.1
    • Product from WormBase gene class htt;
      Confirmed by transcript evidence
    NP_001417864.1
    • Product from WormBase gene class htt;
      Confirmed by transcript evidence
    NP_001417865.1
    • Product from WormBase gene class htt;
      Confirmed by transcript evidence
    NP_001417866.1
    • Product from WormBase gene class htt;
      Confirmed by transcript evidence
    NP_509663.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      9908794..9917448 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077262.5 → NP_509663.3  Serine/threonine-protein kinase TOR [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509663.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93547

    2. NM_001430926.1 → NP_001417864.1  HunTingTin gene family member [Caenorhabditis elegans]

      Status: REVIEWED

    3. NM_001430925.1 → NP_001417862.1  HunTingTin gene family member [Caenorhabditis elegans]

      Status: REVIEWED

    4. NM_001430927.1 → NP_001417866.1  HunTingTin gene family member [Caenorhabditis elegans]

      Status: REVIEWED

    5. NM_001430928.1 → NP_001417863.1  HunTingTin gene family member [Caenorhabditis elegans]

      Status: REVIEWED

    6. NM_001430929.1 → NP_001417865.1  HunTingTin gene family member [Caenorhabditis elegans]

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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