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    Tsnaxip1 translin-associated factor X (Tsnax) interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 72236, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tsnaxip1provided by MGI
    Official Full Name
    translin-associated factor X (Tsnax) interacting protein 1provided by MGI
    Primary source
    MGI:MGI:1919486
    See related
    Ensembl:ENSMUSG00000031893 AllianceGenome:MGI:1919486
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    TXI1; 1700016K08Rik
    Summary
    Predicted to be involved in cell differentiation and spermatogenesis. Located in cytoplasm. Is expressed in brain; gonad; lateral ventricle choroid plexus; and lung. Orthologous to human TSNAXIP1 (translin associated factor X interacting protein 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 54.7) See more
    Orthologs
    human all
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    Genomic context

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    See Tsnaxip1 in Genome Data Viewer
    Location:
    8 D3; 8 53.04 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (106554343..106571310)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105827711..105844678)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4933405L10 gene Neighboring gene STARR-positive B cell enhancer ABC_E6678 Neighboring gene enkurin domain containing 1 Neighboring gene glucose-fructose oxidoreductase domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E8850 Neighboring gene RAN binding protein 10 Neighboring gene STARR-positive B cell enhancer ABC_E2272 Neighboring gene STARR-positive B cell enhancer ABC_E2875 Neighboring gene STARR-positive B cell enhancer ABC_E3799 Neighboring gene centromere protein T Neighboring gene STARR-seq mESC enhancer starr_22544 Neighboring gene THAP domain containing 11 Neighboring gene STARR-seq mESC enhancer starr_22545 Neighboring gene nuclear transport factor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Testis-specific proteins, TSNAXIP1 and 1700010I14RIK, are important for sperm motility and male fertility in mice. Kaneda Y, et al. Andrology, 2023 Jul. PMID 36598146, Free PMC Article
    2. Identification and characterization of cDNAs encoding four novel proteins that interact with translin associated factor-X. Bray JD, et al. Genomics, 2002 Jun. PMID 12036294
    3. Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. Keegan CE, et al. Hum Mol Genet, 2005 Jan 1. PMID 15537664
    4. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
    5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC118240

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    translin-associated factor X-interacting protein 1
    Names
    trax-interacting protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024445.4 → NP_077765.1  translin-associated factor X-interacting protein 1

      See identical proteins and their annotated locations for NP_077765.1

      Status: PROVISIONAL

      Source sequence(s)
      AC116569, AC152826
      Consensus CDS
      CCDS22614.1
      UniProtKB/Swiss-Prot
      Q99P25, Q9DA98
      UniProtKB/TrEMBL
      A0A1D5RMC0
      Related
      ENSMUSP00000034365.5, ENSMUST00000034365.5
      Conserved Domains (1) summary
      pfam15739
      Location:100 → 203
      TSNAXIP1_N; Translin-associated factor X-interacting N-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      106554343..106571310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248511.3 → XP_011246813.1  translin-associated factor X-interacting protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5RMC0
      Conserved Domains (2) summary
      pfam15739
      Location:99 → 202
      TSNAXIP1_N; Translin-associated factor X-interacting N-terminus
      pfam15742
      Location:151 → 348
      DUF4686; Domain of unknown function (DUF4686)

    2. XM_011248512.3 → XP_011246814.1  translin-associated factor X-interacting protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5RMC0
      Conserved Domains (2) summary
      pfam15739
      Location:94 → 197
      TSNAXIP1_N; Translin-associated factor X-interacting N-terminus
      pfam15742
      Location:146 → 343
      DUF4686; Domain of unknown function (DUF4686)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99P25.2 GenPept UniProtKB/Swiss-Prot:Q99P25

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