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    LIP1 lipase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816012, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LIP1
    Official Full Name
    lipase 1
    Primary source
    TAIR:AT2G15230
    Locus tag
    AT2G15230
    See related
    Araport:AT2G15230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATLIP1; F15A23.3; F15A23_3; lipase 1
    Summary
    Lipase active on medium and short chain triacylglycerols, but not on phospho- or galactolipids. Active between pH4 and 7 with an optimum at pH6. Knock-out mutant has not obvious phenotype. Predicted to be extracellular.
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    Genomic context

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    See LIP1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (6612480..6615457)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Plant basic secretory protein (BSP) family protein Neighboring gene ncRNA Neighboring gene UNC-50 family protein Neighboring gene pseudo Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of a triacylglycerol lipase in Arabidopsis homologous to mammalian acid lipases. El-Kouhen K, et al. FEBS Lett, 2005 Nov 7. PMID 16226259
    2. Arabidopsis class A S-acyl transferases modify the pollen receptors LIP1 and PRK1 to regulate pollen tube guidance. Xiang X, et al. Plant Cell, 2024 Sep 3. PMID 38635962,
    3. Arabidopsis DELLA and two HD-ZIP transcription factors regulate GA signaling in the epidermis through the L1 box cis-element. Rombolá-Caldentey B, et al. Plant Cell, 2014 Jul. PMID 24989044, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_127084.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables galactolipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables phospholipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables triacylglycerol lipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycerolipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of seed dormancy process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of seed germination IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to gibberellin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in extracellular space TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lipase 1
    NP_179126.2
    • lipase 1 (LIP1); CONTAINS InterPro DOMAIN/s: AB-hydrolase-associated lipase region (InterPro:IPR006693), Alpha/beta hydrolase fold-1 (InterPro:IPR000073); BEST Arabidopsis thaliana protein match is: Myzus persicae-induced lipase 1 (TAIR:AT5G14180.1); Has 1912 Blast hits to 1877 proteins in 247 species: Archae - 0; Bacteria - 112; Metazoa - 1231; Fungi - 287; Plants - 167; Viruses - 0; Other Eukaryotes - 115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6612480..6615457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127084.3 → NP_179126.2  lipase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179126.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1H5B7, Q71DJ5, Q9SKL5
      UniProtKB/TrEMBL
      A0A5S9WY84, A0A654ET12
      Conserved Domains (1) summary
      PLN02872
      Location:6 → 393
      PLN02872; triacylglycerol lipase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q71DJ5.1

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