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    CENPA centromere protein A [ Pan troglodytes (chimpanzee) ]

    Gene ID: 459086, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CENPAprovided by VGNC
    Official Full Name
    centromere protein Aprovided by VGNC
    Primary source
    VGNC:VGNC:191
    Locus tag
    CK820_G0009561
    See related
    Ensembl:ENSPTRG00000011740
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See CENPA in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 12 NC_072410.2 (96055654..96070595, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (26782621..26797573)

    Chromosome 12 - NC_072410.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107973408 Neighboring gene microtubule associated protein RP/EB family member 3 Neighboring gene dihydropyrimidinase like 5 Neighboring gene solute carrier family 35 member F6 Neighboring gene potassium two pore domain channel subfamily K member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone H3-like centromeric protein A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      96055654..96070595 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003308914.5 → XP_003308962.1  histone H3-like centromeric protein A isoform X2

      See identical proteins and their annotated locations for XP_003308962.1

      UniProtKB/TrEMBL
      A0A2I3SW34, A0A2J8NL30, A0A6D2WRX5
      Related
      ENSPTRP00000081186.1
      Conserved Domains (1) summary
      smart00428
      Location:32 → 135
      H3; Histone H3

    2. XM_003308915.6 → XP_003308963.1  histone H3-like centromeric protein A isoform X1

      See identical proteins and their annotated locations for XP_003308963.1

      UniProtKB/TrEMBL
      A0A2J8NL19, A0A6D2XZ96, K7CSQ3
      Related
      ENSPTRP00000091842.1
      Conserved Domains (2) summary
      pfam16496
      Location:3 → 38
      SWIRM-assoc_2; SWIRM-associated domain at the N-terminal
      cl23735
      Location:32 → 109
      H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...

    RNA

    1. XR_678016.5 RNA Sequence

    2. XR_678017.5 RNA Sequence

    3. XR_010149177.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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