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    mapk14.S mitogen-activated protein kinase 14 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 379992, updated on 18-Sep-2024

    Summary

    Official Symbol
    mapk14.S
    Official Full Name
    mitogen-activated protein kinase 14 S homeolog
    Primary source
    Xenbase:XB-GENE-1018624
    Locus tag
    XELAEV_18014868mg
    See related
    EnsemblRapid:ENSXLAG00005001698
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    p38; csbp; mxi2; sapk2; mapk14; sapk2a; mapk14a; p38-alpha
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    Genomic context

    See mapk14.S in Genome Data Viewer
    Location:
    chromosome: 2S
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (59273083..59369384)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (55222519..55319006)

    Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene colipase-like Neighboring gene SRSF protein kinase 1 S homeolog Neighboring gene zinc finger CCCH-type containing 11A S homeolog Neighboring gene ATPase plasma membrane Ca2+ transporting 4 S homeolog

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • MGC69036

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables MAP kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within intracellular signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within p38MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within p38MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of myoblast differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within positive regulation of myoblast fusion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within positive regulation of myotube differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mitogen-activated protein kinase 14
    Names
    MAP kinase 14
    MAP kinase 2
    MAPK 14
    MAPK p38
    MPK2
    Mitogen-activated protein kinase 2
    mitogen-activated Mitogen-activated protein kinase 2
    mitogen-activated protein kinase p38 alpha
    NP_001080300.1
    XP_018103537.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001086831.1NP_001080300.1  mitogen-activated protein kinase 14

      See identical proteins and their annotated locations for NP_001080300.1

      Status: PROVISIONAL

      Source sequence(s)
      X80751
      UniProtKB/Swiss-Prot
      P47812, Q5D076
      UniProtKB/TrEMBL
      A0A974DGZ3, D2KW21
      Related
      ENSXLAP00005005032.1, ENSXLAT00005005138.1
      Conserved Domains (2) summary
      cd07877
      Location:7351
      STKc_p38alpha; Catalytic domain of the Serine/Threonine Kinase, p38alpha Mitogen-Activated Protein Kinase (also called MAPK14)
      smart00220
      Location:25309
      S_TKc; Serine/Threonine protein kinases, catalytic domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      59273083..59369384
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018248048.2XP_018103537.1  mitogen-activated protein kinase 14 isoform X1

      UniProtKB/TrEMBL
      A0A8J0UHZ4
      Related
      ENSXLAP00005005033.1, ENSXLAT00005005139.1