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    SKG1 Skg1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853975, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SKG1
    Official Full Name
    Skg1p
    Primary source
    SGD:S000001808
    Locus tag
    YKR100C
    See related
    AllianceGenome:SGD:S000001808; FungiDB:YKR100C; VEuPathDB:YKR100C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YKR099C-A
    Summary
    Involved in fungal-type cell wall organization. Located in cellular bud tip. Part of incipient cellular bud site. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See SKG1 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (638901..639968, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene ubiquitin-specific protease UBP11 Neighboring gene Bas1p Neighboring gene Sir1p Neighboring gene Flo10p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition. Tomishige N, et al. Yeast, 2005 Jan 30. PMID 15645486
    2. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Stevenson LF, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11274415, Free PMC Article
    3. Complete DNA sequence of yeast chromosome XI. Dujon B, et al. Nature, 1994 Jun 2. PMID 8196765
    4. A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae. Ming Sun S, et al. J Cell Sci, 2020 May 22. PMID 32299836, Free PMC Article
    5. A genome-wide enhancer screen implicates sphingolipid composition in vacuolar ATPase function in Saccharomyces cerevisiae. Finnigan GC, et al. Genetics, 2011 Mar. PMID 21196517, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SKG1 encodes a novel protein that affects the cell wall polymer composition in the growing region of the cell.
      Title: SKG1, a suppressor gene of synthetic lethality of kex2Deltagas1Delta mutations, encodes a novel membrane protein that affects cell wall composition.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cellular bud HDA PubMed 
    located_in cellular bud membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cellular bud tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in incipient cellular bud site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Skg1p
    NP_013026.2
    • Transmembrane protein with a role in cell wall polymer composition; localizes on inner surface of plasma membrane at bud and in daughter cell; SKG1 has a paralog, AIM20, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      638901..639968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179890.1 → NP_013026.2  TPA: Skg1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013026.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A7A060, D6VXG1, P36169, Q86ZT0
      UniProtKB/TrEMBL
      N1P120
      Conserved Domains (1) summary
      pfam08693
      Location:2 → 34
      SKG6; Transmembrane alpha-helix domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36169.2

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