U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    POTEB2 POTE ankyrin domain family member B2 [ Homo sapiens (human) ]

    Gene ID: 100287399, updated on 10-Oct-2024

    Summary

    Official Symbol
    POTEB2provided by HGNC
    Official Full Name
    POTE ankyrin domain family member B2provided by HGNC
    Primary source
    HGNC:HGNC:48327
    See related
    Ensembl:ENSG00000230031 AllianceGenome:HGNC:48327
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    POTEB; POTE-15
    Expression
    Restricted expression toward testis (RPKM 6.0) See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See POTEB2 in Genome Data Viewer
    Location:
    15q11.2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (20835372..20866314, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (19801345..19869004)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (21040701..21071643, complement)

    Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene GRAM domain containing 4 pseudogene 5 Neighboring gene microRNA 3118-2 Neighboring gene RNA, U6 small nuclear 749, pseudogene Neighboring gene vomeronasal 1 receptor 60 pseudogene Neighboring gene vomeronasal 1 receptor 61 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    POTE ankyrin domain family member B2
    Names
    ANKRD26-like family B member 1
    POTE ankyrin domain family member B
    Prostate, ovary, testis-expressed protein on chromosome 15

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001277303.1NP_001264232.1  POTE ankyrin domain family member B2

      See identical proteins and their annotated locations for NP_001264232.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer variant and encodes the supported protein.
      Source sequence(s)
      AC012414, BC101007
      Consensus CDS
      CCDS59248.1
      UniProtKB/Swiss-Prot
      A0A0A6YYL3, H3BUK9, Q495V7
      Related
      ENSP00000456953.1, ENST00000454856.4
      Conserved Domains (4) summary
      cd00204
      Location:130255
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:201232
      ANK; ANK repeat [structural motif]
      pfam14915
      Location:489542
      CCDC144C; CCDC144C protein coiled-coil region
      cl25732
      Location:412542
      SMC_N; RecF/RecN/SMC N terminal domain

    RNA

    1. NR_102390.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two internal exons, compared to variant 1. This variant is represented as non-coding because the use of the expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      BC101007
      Related
      ENST00000438063.6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

      Range
      20835372..20866314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006720354.4XP_006720417.1  POTE ankyrin domain family member B2 isoform X1

      See identical proteins and their annotated locations for XP_006720417.1

      UniProtKB/TrEMBL
      D7UEQ8
      Conserved Domains (4) summary
      cd00204
      Location:130255
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:140232
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:106156
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:201232
      ANK; ANK repeat [structural motif]
    2. XM_017021853.2XP_016877342.1  POTE ankyrin domain family member B2 isoform X3

      UniProtKB/TrEMBL
      A0A0G2JQ08
    3. XM_011543793.3XP_011542095.1  POTE ankyrin domain family member B2 isoform X2

      See identical proteins and their annotated locations for XP_011542095.1

      UniProtKB/TrEMBL
      A0A0G2JQ08
      Conserved Domains (4) summary
      cd00204
      Location:130255
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:140232
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:106156
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:201232
      ANK; ANK repeat [structural motif]

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_021160017.1 Reference GRCh38.p14 PATCHES

      Range
      1079644..1111686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054332568.1XP_054188543.1  POTE ankyrin domain family member B2 isoform X4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060939.1 Alternate T2T-CHM13v2.0

      Range
      19801345..19869004
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054377166.1XP_054233141.1  POTE ankyrin domain family member B2 isoform X5

      UniProtKB/TrEMBL
      A0AAG2TVG0
    2. XM_054377167.1XP_054233142.1  POTE ankyrin domain family member B2 isoform X1

    3. XM_054377168.1XP_054233143.1  POTE ankyrin domain family member B2 isoform X2