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    stk24.L serine/threonine kinase 24 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 444155, updated on 4-Nov-2024

    Summary

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    Official Symbol
    stk24.L
    Official Full Name
    serine/threonine kinase 24 L homeolog
    Primary source
    Xenbase:XB-GENE-987148
    Locus tag
    XELAEV_18013129mg
    See related
    EnsemblRapid:ENSXLAG00005000592 AllianceGenome:Xenbase:XB-GENE-987148
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    mst3; stk3; mst3b; ste20; stk24
    Summary
    Predicted to enable ATP binding activity; metal ion binding activity; and protein serine/threonine kinase activity. Predicted to act upstream of or within negative regulation of cell migration and protein phosphorylation. Predicted to be located in cytoplasm. Orthologous to human STK24 (serine/threonine kinase 24). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See stk24.L in Genome Data Viewer
    Location:
    chromosome: 2L
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (126345602..126375222)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (120494708..120523562)

    Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene dedicator of cytokinesis 9 L homeolog Neighboring gene solute carrier family 15 (oligopeptide transporter), member 1 L homeolog Neighboring gene FERM, ARH/RhoGEF and pleckstrin domain protein 1 L homeolog Neighboring gene importin 5 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC80614

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine kinase 24 L homeolog
    Names
    serine/threonine kinase 24 (STE20 homolog)
    NP_001085728.1
    XP_018100537.1
    XP_041436912.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001092259.1 → NP_001085728.1  serine/threonine kinase 24 L homeolog

      See identical proteins and their annotated locations for NP_001085728.1

      Status: PROVISIONAL

      Source sequence(s)
      BC073258
      UniProtKB/TrEMBL
      A0A974DNZ2, Q6GP83
      Related
      ENSXLAP00005001641.1, ENSXLAT00005001681.1
      Conserved Domains (2) summary
      smart00220
      Location:24 → 274
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06641
      Location:19 → 295
      STKc_MST3; Catalytic domain of the Serine/Threonine Kinase, Mammalian Ste20-like protein kinase 3

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      126345602..126375222
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018245048.2 → XP_018100537.1  serine/threonine kinase 24 L homeolog isoform X1

      UniProtKB/TrEMBL
      A0A8J0U3U9
      Related
      ENSXLAP00005001645.1, ENSXLAT00005001685.1

    2. XM_041580978.1 → XP_041436912.1  serine/threonine kinase 24 L homeolog isoform X2

      UniProtKB/TrEMBL
      A0A8J1M5E5
      Conserved Domains (1) summary
      cl21453
      Location:1 → 197
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version

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