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    cyp2a6.3.L cytochrome P450 family 2 subfamily A member 6 gene 3 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 493578, updated on 4-Nov-2024

    Summary

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    Official Symbol
    cyp2a6.3.L
    Official Full Name
    cytochrome P450 family 2 subfamily A member 6 gene 3 L homeolog
    Primary source
    Xenbase:XB-GENE-5904006
    Locus tag
    XELAEV_18039331mg
    See related
    EnsemblRapid:ENSXLAG00005033938 AllianceGenome:Xenbase:XB-GENE-5904006
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    LOC100497184.L
    Summary
    Predicted to enable heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to act upstream of or within epoxygenase P450 pathway and xenobiotic metabolic process. Predicted to be located in cytoplasm; intracellular membrane-bounded organelle; and membrane. Orthologous to human CYP2A6 (cytochrome P450 family 2 subfamily A member 6). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See cyp2a6.3.L in Genome Data Viewer
    Location:
    chromosome: 8L
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (70394847..70414841, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (56899168..56918958, complement)

    Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 2 subfamily A member 6 gene 5 L homeolog Neighboring gene cytochrome P450 family 2 subfamily A member 6 gene 4 L homeolog Neighboring gene cytochrome P450 family 2 subfamily a member 6 gene 2 L homeolog Neighboring gene uncharacterized protein MGC68450

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC80550

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables arachidonate epoxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within epoxygenase P450 pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within xenobiotic metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450 family 2 subfamily A member 6 gene 3 L homeolog
    Names
    cytochrome P450 2G1-like L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001094469.1 → NP_001087938.1  cytochrome P450 family 2 subfamily A member 6 gene 3 L homeolog

      See identical proteins and their annotated locations for NP_001087938.1

      Status: PROVISIONAL

      Source sequence(s)
      BC077850
      UniProtKB/TrEMBL
      Q6DCY4
      Related
      ENSXLAP00005101386.1, ENSXLAT00005103363.1
      Conserved Domains (1) summary
      pfam00067
      Location:41 → 487
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      70394847..70414841 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041572094.1 → XP_041428028.1  cytochrome P450 family 2 subfamily A member 6 gene 3 L homeolog isoform X1

      UniProtKB/TrEMBL
      A0A8J1LEQ6
      Related
      ENSXLAP00005101416.1, ENSXLAT00005103393.1
      Conserved Domains (1) summary
      cl12078
      Location:38 → 452
      p450; Cytochrome P450
    Nucleotide Protein Strain
    Heading Accession and Version

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