LOC100125646 catechol-O-methyltransferase [Zea mays] - Gene

Summary

Gene symbol: LOC100125646
Gene description: catechol-O-methyltransferase
Locus tag: ZEAMMB73_Zm00001d049541
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Zea mays
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Also known as: OMT; comt; CAOMT; ZmOMT1; GRMZM5G814904
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Genomic context

Location:: chromosome: 4

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
103	current	Zm-B73-REFERENCE-NAM-5.0 (GCF_902167145.1)	4	NC_050099.1 (34198838..34201132, complement)
102.20200423	previous assembly	B73 RefGen_v4 (GCF_000005005.2)	4	NC_024462.2 (33817801..33820095, complement)

Chromosome 4 - NC_050099.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This study investigated 55 exotic caffeic acid 3-O-methyltransferase alleles and discovered >400 polymorphisms in a 2.2 kb region with pairwise nucleotide diversity (pi) up to 0.017, much higher than reported pi values of various genes in inbred lines.
Title: Extensive genetic diversity and low linkage disequilibrium within the COMT locus in maize exotic populations.
Expression of the caffeic acid O-methyltransferase (COMT) gene was heavily reduced, especially in the younger lignifying tissues of the ear internode.
Title: Expression of cell wall related genes in basal and ear internodes of silking brown-midrib-3, caffeic acid O-methyltransferase (COMT) down-regulated, and normal maize plants.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables O-methyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables S-adenosylmethionine-dependent methyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in methylation	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: caffeic acid 3-O-methyltransferase

Names: AC196475.3_FGT004; Flavone 3'-O-methyltransferase 1; O-methyltransferase; S-adenosysl-L-methionine:caffeic acid 3-O-methyltransferase; brown midrib3; flavonoid O-methyltransferase; quercetin 3-O-methyltransferase 1; tricin synthase

NP_001106047.1

EC 2.1.1.175

EC 2.1.1.68

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001112577.2 → NP_001106047.1 caffeic acid 3-O-methyltransferase

See identical proteins and their annotated locations for NP_001106047.1

Status: VALIDATED

Source sequence(s)

BM382769, EU941801, EU965480

UniProtKB/Swiss-Prot

Q06509, Q6VWG3

UniProtKB/TrEMBL

B6TKG5

Conserved Domains (2) summary

pfam00891
Location:129 → 349

Methyltransf_2; O-methyltransferase

pfam08100
Location:31 → 87

Dimerisation; Dimerisation domain

RefSeqs of Annotated Genomes: Zea mays Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Zm-B73-REFERENCE-NAM-5.0 Primary Assembly

Genomic

NC_050099.1 Reference Zm-B73-REFERENCE-NAM-5.0 Primary Assembly

Range

34198838..34201132 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001279714.1: Suppressed sequence

Description

NM_001279714.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.