U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    PIK3R3 phosphoinositide-3-kinase regulatory subunit 3 [ Chrysemys picta bellii (western painted turtle) ]

    Gene ID: 101947423, updated on 18-Nov-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PIK3R3
    Gene description
    phosphoinositide-3-kinase regulatory subunit 3
    See related
    Ensembl:ENSCPBG00000005617
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Chrysemys picta bellii (sub-species: bellii)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Chrysemys
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PIK3R3 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_05 current ASM1138683v2 (GCF_011386835.1) 8 NC_088798.1 (4377900..4691710, complement)
    103 previous assembly Chrysemys_picta_BioNano-3.0.4 (GCF_000241765.4) Unplaced Scaffold NW_024885899.1 (5910282..6238617)

    Chromosome 8 - NC_088798.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135972959 Neighboring gene microtubule associated serine/threonine kinase 2 Neighboring gene uncharacterized LOC101948418 Neighboring gene uncharacterized LOC135972962 Neighboring gene uncharacterized LOC135972961 Neighboring gene tetraspanin 1 Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in insulin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    phosphatidylinositol 3-kinase regulatory subunit gamma

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_011386835.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1138683v2

    Genomic

    1. NC_088798.1 Reference ASM1138683v2

      Range
      4377900..4691710 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042845026.2 → XP_042700960.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1

      UniProtKB/TrEMBL
      A0A8C3FEC6
      Conserved Domains (5) summary
      cd09930
      Location:617 → 720
      SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
      cd09942
      Location:323 → 433
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cd12925
      Location:438 → 598
      iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
      cl02570
      Location:117 → 288
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl17036
      Location:7 → 79
      SH3; Src Homology 3 domain superfamily

    2. XM_005302995.5 → XP_005303052.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1

      UniProtKB/TrEMBL
      A0A8C3FEC6
      Related
      ENSCPBP00000007128.1
      Conserved Domains (5) summary
      cd09930
      Location:617 → 720
      SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
      cd09942
      Location:323 → 433
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cd12925
      Location:438 → 598
      iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
      cl02570
      Location:117 → 288
      RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
      cl17036
      Location:7 → 79
      SH3; Src Homology 3 domain superfamily

    3. XM_065553757.1 → XP_065409829.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1

      UniProtKB/TrEMBL
      A0A8C3FEC6

    4. XM_005302997.5 → XP_005303054.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2

      UniProtKB/TrEMBL
      A0A8C3FD84, A0A8C3H7T0
      Related
      ENSCPBP00000007137.1
      Conserved Domains (4) summary
      cd09930
      Location:352 → 455
      SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
      cd09942
      Location:58 → 168
      SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
      cd12925
      Location:173 → 333
      iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
      pfam16454
      Location:172 → 331
      PI3K_P85_iSH2; Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.