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    Lta4h leukotriene A4 hydrolase [ Chinchilla lanigera (long-tailed chinchilla) ]

    Gene ID: 102007852, updated on 10-Mar-2024

    Summary

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    Gene symbol
    Lta4h
    Gene description
    leukotriene A4 hydrolase
    See related
    Ensembl:ENSCLAG00000011828
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Chinchilla lanigera
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Chinchillidae; Chinchilla
    Orthologs
    human mouse all
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    Genomic context

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    See Lta4h in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    101 current ChiLan1.0 (GCF_000276665.1) Unplaced Scaffold NW_004955405.1 (32345005..32377685, complement)

    NW_004955405.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 38 Neighboring gene amidohydrolase domain containing 1 Neighboring gene histidine ammonia-lyase Neighboring gene uncharacterized LOC106149748 Neighboring gene uncharacterized LOC102008492 Neighboring gene uncharacterized LOC102008179

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004955405.1 Unplaced Scaffold Reference ChiLan1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables aminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables epoxide hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables leukotriene-A4 hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in leukotriene biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leukotriene A-4 hydrolase
    Names
    LTA-4 hydrolase
    LTA4 hydrolase
    Leukotriene A(4) hydrolase
    NP_001269293.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282364.1 → NP_001269293.1  leukotriene A-4 hydrolase

      See identical proteins and their annotated locations for NP_001269293.1

      Status: PROVISIONAL

      Source sequence(s)
      AY462137
      UniProtKB/Swiss-Prot
      Q6S9C8
      UniProtKB/TrEMBL
      A0A8C2VLA7
      Related
      ENSCLAP00000017226.1, ENSCLAT00000017395.1
      Conserved Domains (3) summary
      cd09599
      Location:17 → 450
      M1_LTA4H; Peptidase M1 family contains leukotriene A4 hydrolase
      TIGR02411
      Location:6 → 608
      leuko_A4_hydro; leukotriene A-4 hydrolase/aminopeptidase
      pfam09127
      Location:468 → 607
      Leuk-A4-hydro_C; Leukotriene A4 hydrolase, C-terminal

    RefSeqs of Annotated Genomes: Chinchilla lanigera Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ChiLan1.0 Primary Assembly

    Genomic

    1. NW_004955405.1 Reference ChiLan1.0 Primary Assembly

      Range
      32345005..32377685 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6S9C8.3 GenPept UniProtKB/Swiss-Prot:Q6S9C8

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