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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001080773.2 → NP_001074242.1 3-phosphoinositide-dependent protein kinase 1 isoform B
See identical proteins and their annotated locations for NP_001074242.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) has an alternate splice site in the 3' region, compared to variant 1. The resulting isoform (B) is shorter and has a distinct C-terminus, compared to isoform A.
- Source sequence(s)
-
AK162677, BQ175596, BY257456
- Consensus CDS
-
CCDS37483.1
- UniProtKB/TrEMBL
- Q3TRL2, Q3UGN6, Q3UHZ0
- Related
- ENSMUSP00000111070.2, ENSMUST00000115411.8
- Conserved Domains (3) summary
-
- smart00220
Location:85 → 345
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd01262
Location:444 → 521
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cd05581
Location:83 → 345
- STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
-
NM_001286662.1 → NP_001273591.1 3-phosphoinositide-dependent protein kinase 1 isoform C
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) has an alternate 5' exon, which results in translation initiation at a downstream start codon, compared to variant 1. The resulting isoform (C) has a shorter N-terminus, compared to isoform A.
- Source sequence(s)
-
AK147835, AK149162, CJ046953, CT010502
- Consensus CDS
-
CCDS70767.1
- UniProtKB/TrEMBL
- F2Z3X6, Q8K3L3
- Related
- ENSMUSP00000061942.7, ENSMUST00000052462.13
- Conserved Domains (2) summary
-
- cd01262
Location:417 → 523
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cd05581
Location:56 → 318
- STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
-
NM_011062.4 → NP_035192.2 3-phosphoinositide-dependent protein kinase 1 isoform A
See identical proteins and their annotated locations for NP_035192.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (A).
- Source sequence(s)
-
AK147149, AK147835, BQ175596, BY257456, CT010502
- Consensus CDS
-
CCDS28474.1
- UniProtKB/Swiss-Prot
- A6H6U3, Q9R1D8, Q9R215, Q9Z2A0
- UniProtKB/TrEMBL
-
Q3UHZ0
- Related
- ENSMUSP00000099991.4, ENSMUST00000102927.10
- Conserved Domains (3) summary
-
- smart00220
Location:85 → 345
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd01262
Location:444 → 550
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cd05581
Location:83 → 345
- STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000083.7 Reference GRCm39 C57BL/6J
- Range
-
24292654..24370957 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017317324.3 → XP_017172813.1 3-phosphoinositide-dependent protein kinase 1 isoform X2
- Conserved Domains (2) summary
-
- cd01262
Location:283 → 389
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cl21453
Location:47 → 184
- PKc_like; Protein Kinases, catalytic domain
-
XM_030249574.2 → XP_030105434.1 3-phosphoinositide-dependent protein kinase 1 isoform X3
- Conserved Domains (2) summary
-
- cd01262
Location:225 → 331
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cl21453
Location:1 → 126
- PKc_like; Protein Kinases, catalytic domain
-
XM_017317326.3 → XP_017172815.1 3-phosphoinositide-dependent protein kinase 1 isoform X1
- UniProtKB/TrEMBL
- F2Z3X6, Q8K3L3
- Conserved Domains (2) summary
-
- cd01262
Location:417 → 523
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cd05581
Location:56 → 318
- STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
-
XM_017317325.3 → XP_017172814.1 3-phosphoinositide-dependent protein kinase 1 isoform X2
- Conserved Domains (2) summary
-
- cd01262
Location:283 → 389
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cl21453
Location:47 → 184
- PKc_like; Protein Kinases, catalytic domain
-
XM_030249575.2 → XP_030105435.1 3-phosphoinositide-dependent protein kinase 1 isoform X3
- Conserved Domains (2) summary
-
- cd01262
Location:225 → 331
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cl21453
Location:1 → 126
- PKc_like; Protein Kinases, catalytic domain
-
XM_017317321.3 → XP_017172810.1 3-phosphoinositide-dependent protein kinase 1 isoform X1
- UniProtKB/TrEMBL
- F2Z3X6, Q8K3L3
- Conserved Domains (2) summary
-
- cd01262
Location:417 → 523
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cd05581
Location:56 → 318
- STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
-
XM_017317320.3 → XP_017172809.1 3-phosphoinositide-dependent protein kinase 1 isoform X1
- UniProtKB/TrEMBL
- F2Z3X6, Q8K3L3
- Conserved Domains (2) summary
-
- cd01262
Location:417 → 523
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cd05581
Location:56 → 318
- STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
-
XM_017317322.1 → XP_017172811.1 3-phosphoinositide-dependent protein kinase 1 isoform X1
- UniProtKB/TrEMBL
- F2Z3X6, Q8K3L3
- Conserved Domains (2) summary
-
- cd01262
Location:417 → 523
- PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
- cd05581
Location:56 → 318
- STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1