U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    Ank1 ankyrin 1, erythroid [ Mus musculus (house mouse) ]

    Gene ID: 11733, updated on 2-Nov-2024

    Summary

    Official Symbol
    Ank1provided by MGI
    Official Full Name
    ankyrin 1, erythroidprovided by MGI
    Primary source
    MGI:MGI:88024
    See related
    Ensembl:ENSMUSG00000031543 AllianceGenome:MGI:88024
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    nb; pale; Ank-1
    Summary
    Predicted to enable several functions, including enzyme binding activity; spectrin binding activity; and transmembrane transporter binding activity. Acts upstream of or within several processes, including erythrocyte development; multicellular organismal-level iron ion homeostasis; and porphyrin-containing compound biosynthetic process. Located in cortical cytoskeleton; membrane; and spectrin-associated cytoskeleton. Is expressed in several structures, including central nervous system; embryo mesenchyme; heart; retina; and skeletal muscle. Used to study hereditary spherocytosis type 1 and malaria. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 21.2), liver E14.5 (RPKM 20.5) and 15 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ank1 in Genome Data Viewer
    Location:
    8 A2; 8 11.42 cM
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (23464852..23640517)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (22974836..23150501)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene K(lysine) acetyltransferase 6A Neighboring gene mitochondrial ribosomal protein L4 pseudogene Neighboring gene LSM6 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene predicted gene 15816 Neighboring gene STARR-seq mESC enhancer starr_20914 Neighboring gene microRNA 3107 Neighboring gene microRNA 486 Neighboring gene NK6 homeobox 3 Neighboring gene predicted gene, 30306 Neighboring gene predicted gene, 30247

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cytoskeletal anchor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cytoskeletal anchor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables spectrin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables spectrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in A band ISO
    Inferred from Sequence Orthology
    more info
     
    located_in M band ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Z disc ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ankyrin-1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ankyrin-1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in axolemma ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cortical cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasmic side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcolemma ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in sarcoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spectrin-associated cytoskeleton IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in spectrin-associated cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ankyrin-1
    Names
    erythrocyte ankyrin
    normoblastic anemia

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110783.3NP_001104253.1  ankyrin-1 isoform 1

      See identical proteins and their annotated locations for NP_001104253.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AI846810, AK147278, AK147483, AK158131, CJ105945
      Consensus CDS
      CCDS52523.1
      UniProtKB/TrEMBL
      A0A0R4J1N7
      Related
      ENSMUSP00000113571.3, ENSMUST00000121802.9
      Conserved Domains (8) summary
      smart00218
      Location:9521056
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      COG0666
      Location:374583
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:365490
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08805
      Location:14421525
      Death_ank1; Death domain of Ankyrin-1
      pfam12796
      Location:342433
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:4798
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:753807
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:700731
      ANK; ANK repeat [structural motif]
    2. NM_001277280.2NP_001264209.1  ankyrin-1 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon and uses an alternate in-frame splice junction in a 3' exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but lacks two alternate internal segments compared to isoform 1.
      Source sequence(s)
      AC126445, AI846810, AK147483, AK158131, CJ105945
      Consensus CDS
      CCDS72099.1
      UniProtKB/Swiss-Prot
      Q02357
      Related
      ENSMUSP00000106316.3, ENSMUST00000110688.9
      Conserved Domains (8) summary
      smart00218
      Location:9441048
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      COG0666
      Location:374583
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:365490
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08805
      Location:14341517
      Death_ank1; Death domain of Ankyrin-1
      pfam12796
      Location:342433
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:4798
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:753807
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:700731
      ANK; ANK repeat [structural motif]
    3. NM_001277281.2NP_001264210.1  ankyrin-1 isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, represents use of an alternate promoter, initiates translation at an alternate start codon, and lacks an alternate in-frame exon compared to variant 1. The encoded isoform (4) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 1.
      Source sequence(s)
      AC126445, AI846810, AK147483, CJ101195, M84756
      Consensus CDS
      CCDS72100.1
      UniProtKB/TrEMBL
      E9QNT8
      Related
      ENSMUSP00000113531.2, ENSMUST00000117662.8
      Conserved Domains (8) summary
      smart00218
      Location:9071011
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      COG0666
      Location:337546
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:328453
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08805
      Location:13971480
      Death_ank1; Death domain of Ankyrin-1
      pfam12796
      Location:305396
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:1061
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:716770
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:663694
      ANK; ANK repeat [structural motif]
    4. NM_001277284.2NP_001264213.1  ankyrin-1 isoform 5

      See identical proteins and their annotated locations for NP_001264213.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) has an alternate 5' exon, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction in a 3' exon compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus, lacks an alternate internal segment, and contains an alternate internal segment compared to isoform 1.
      Source sequence(s)
      AC126445, AI846810, AK147483, BC079910, CJ101195
      Consensus CDS
      CCDS72101.1
      UniProtKB/TrEMBL
      Q0VGY9
      Related
      ENSMUSP00000113656.2, ENSMUST00000117296.8
      Conserved Domains (8) summary
      smart00218
      Location:9071011
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      COG0666
      Location:337546
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:328453
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08805
      Location:13971480
      Death_ank1; Death domain of Ankyrin-1
      pfam12796
      Location:305396
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:1061
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:716770
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:663694
      ANK; ANK repeat [structural motif]
    5. NM_001277286.2NP_001264215.1  ankyrin-1 isoform 6

      See identical proteins and their annotated locations for NP_001264215.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR, represents use of an alternate promoter, initiates translation at an alternate start codon, and lacks an alternate in-frame segment compared to variant 1. The encoded isoform (6) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 1.
      Source sequence(s)
      AI846810, AK147483, AK147597, X69063
      Consensus CDS
      CCDS72102.1
      UniProtKB/TrEMBL
      B7ZW98
      Related
      ENSMUSP00000133322.2, ENSMUST00000173248.8
      Conserved Domains (8) summary
      smart00218
      Location:9231027
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      COG0666
      Location:345554
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:336461
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08805
      Location:14131496
      Death_ank1; Death domain of Ankyrin-1
      pfam12796
      Location:313404
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:1869
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:724778
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:671702
      ANK; ANK repeat [structural motif]
    6. NM_001277289.2NP_001264218.1  ankyrin-1 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR, represents use of an alternate promoter compared and initiates translation at an alternate start codon to variant 1. The encoded isoform (7) has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC126445, AI846810, AK147483, AK147597, X69063
      Consensus CDS
      CCDS72103.1
      UniProtKB/TrEMBL
      D3YTV8
      Related
      ENSMUSP00000112850.2, ENSMUST00000118733.8
      Conserved Domains (8) summary
      smart00218
      Location:9231027
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      COG0666
      Location:345554
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:336461
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08805
      Location:14131496
      Death_ank1; Death domain of Ankyrin-1
      pfam12796
      Location:313404
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:1869
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:724778
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:671702
      ANK; ANK repeat [structural motif]
    7. NM_001310436.1NP_001297365.1  ankyrin-1 isoform 8

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) has multiple differences compared to variant 1. These differences result in a distinct 5' UTR, translation initiation at an alternate start codon, and a novel 3' coding region. The encoded isoform (8) is shorter than and has distinct N- and C-termini compared to isoform 1.
      Source sequence(s)
      AI846810, AK134267, AK147483, BC079910, U73972
      Consensus CDS
      CCDS80865.1
      UniProtKB/Swiss-Prot
      Q02357
      UniProtKB/TrEMBL
      Q0VGY9
      Related
      ENSMUSP00000033947.9, ENSMUST00000033947.15
    8. NM_001310437.1NP_001297366.1  ankyrin-1 isoform 9

      See identical proteins and their annotated locations for NP_001297366.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon compared to variant 1. It encodes isoform 9, which has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AI846810, AK147483, U73972
      Consensus CDS
      CCDS80864.1
      UniProtKB/Swiss-Prot
      Q02357
      Related
      ENSMUSP00000112966.2, ENSMUST00000121075.8
    9. NM_031158.4NP_112435.2  ankyrin-1 isoform 2

      See identical proteins and their annotated locations for NP_112435.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, represents use of an alternate promoter, initiates translation at an alternate start codon, and lacks an alternate in-frame segment compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform 1.
      Source sequence(s)
      AI846810, AK147278, AK147483, X69063
      Consensus CDS
      CCDS22187.1
      UniProtKB/TrEMBL
      G5E8J2
      Related
      ENSMUSP00000081051.5, ENSMUST00000084038.11
      Conserved Domains (8) summary
      smart00218
      Location:9231027
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      COG0666
      Location:345554
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:336461
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd08805
      Location:14131496
      Death_ank1; Death domain of Ankyrin-1
      pfam12796
      Location:313404
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:1869
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:724778
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:671702
      ANK; ANK repeat [structural motif]

    RNA

    1. NR_102385.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR, represents use of an alternate promoter, and has multiple differences compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AI846810, AK147483, AK147597, X69063
      Related
      ENSMUST00000173573.8
    2. NR_102386.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR, represents use of an alternate promoter, and has multiple differences compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AI846810, AK147483, X69063
      Related
      ENSMUST00000123418.8

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      23464852..23640517
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508990.2XP_006509053.1  ankyrin-1 isoform X2

      Conserved Domains (9) summary
      smart00218
      Location:9521056
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:415625
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:123468
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14421525
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:700731
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:49140
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:767819
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12771406
      UPA_2; UPA domain
      cl39094
      Location:579792
      Ank_2; Ankyrin repeats (3 copies)
    2. XM_006509000.2XP_006509063.1  ankyrin-1 isoform X12

      UniProtKB/TrEMBL
      D3Z5M4
      Related
      ENSMUSP00000113495.3, ENSMUST00000117270.9
      Conserved Domains (9) summary
      smart00218
      Location:9521056
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:415625
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:123468
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14421525
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:700731
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:49140
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:767819
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12771406
      UPA_2; UPA domain
      cl39094
      Location:579792
      Ank_2; Ankyrin repeats (3 copies)
    3. XM_006508989.4XP_006509052.1  ankyrin-1 isoform X1

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    4. XM_006508991.5XP_006509054.1  ankyrin-1 isoform X3

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    5. XM_006508992.5XP_006509055.1  ankyrin-1 isoform X4

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    6. XM_006508997.5XP_006509060.1  ankyrin-1 isoform X9

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    7. XM_006508993.5XP_006509056.1  ankyrin-1 isoform X5

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    8. XM_030243250.2XP_030099110.1  ankyrin-1 isoform X13

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    9. XM_006508994.5XP_006509057.1  ankyrin-1 isoform X6

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    10. XM_006508998.5XP_006509061.1  ankyrin-1 isoform X10

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    11. XM_006509001.5XP_006509064.1  ankyrin-1 isoform X14

      Conserved Domains (9) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14601543
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12951424
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    12. XM_006508995.5XP_006509058.1  ankyrin-1 isoform X7

      Related
      ENSMUSP00000117966.3, ENSMUST00000141784.9
      Conserved Domains (9) summary
      smart00218
      Location:9621066
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14521535
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12871416
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    13. XM_006508999.5XP_006509062.1  ankyrin-1 isoform X11

      Conserved Domains (9) summary
      smart00218
      Location:9621066
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14521535
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12871416
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    14. XM_006509002.5XP_006509065.1  ankyrin-1 isoform X15

      Conserved Domains (9) summary
      smart00218
      Location:9621066
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14521535
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12871416
      UPA_2; UPA domain
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    15. XM_006509003.5XP_006509066.1  ankyrin-1 isoform X16

      Conserved Domains (7) summary
      smart00218
      Location:9701074
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:433643
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:141486
      PHA02876; ankyrin repeat protein; Provisional
      sd00045
      Location:718749
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:67158
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:785837
      Ank_4; Ankyrin repeats (many copies)
      cl39094
      Location:597810
      Ank_2; Ankyrin repeats (3 copies)
    16. XM_006508996.3XP_006509059.1  ankyrin-1 isoform X8

      Conserved Domains (9) summary
      smart00218
      Location:9231027
      ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
      PHA02875
      Location:386596
      PHA02875; ankyrin repeat protein; Provisional
      PHA02876
      Location:94439
      PHA02876; ankyrin repeat protein; Provisional
      cd08805
      Location:14131496
      Death_ank1; Death domain of Ankyrin-1
      sd00045
      Location:671702
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:20111
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:738790
      Ank_4; Ankyrin repeats (many copies)
      pfam17809
      Location:12481377
      UPA_2; UPA domain
      cl39094
      Location:550763
      Ank_2; Ankyrin repeats (3 copies)
    17. XM_036153729.1XP_036009622.1  ankyrin-1 isoform X17

    RNA

    1. XR_378776.5 RNA Sequence