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    Cep15 centrosomal protein 15 [ Mus musculus (house mouse) ]

    Gene ID: 218734, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Cep15provided by MGI
    Official Full Name
    centrosomal protein 15provided by MGI
    Primary source
    MGI:MGI:1917937
    See related
    Ensembl:ENSMUSG00000033111 AllianceGenome:MGI:1917937
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3830406C13Rik
    Summary
    Predicted to be located in cilium. Orthologous to human CEP15 (centrosomal protein 15). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 3.5), testis adult (RPKM 2.2) and 24 other tissues See more
    Orthologs
    human all
    NEW
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    Genomic context

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    See Cep15 in Genome Data Viewer
    Location:
    14 A1; 14 6.34 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (10147278..10185610, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (12284153..12324492)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35954 Neighboring gene predicted gene, 24578 Neighboring gene Fez family zinc finger 2 Neighboring gene protein tyrosine phosphatase receptor type G Neighboring gene STARR-seq mESC enhancer starr_35952 Neighboring gene STARR-seq mESC enhancer starr_35951 Neighboring gene predicted gene, 53822 Neighboring gene STARR-seq mESC enhancer starr_35947 Neighboring gene STARR-seq mESC enhancer starr_35940 Neighboring gene STARR-seq mESC enhancer starr_35939 Neighboring gene STARR-seq mESC enhancer starr_35937 Neighboring gene predicted gene, 52128

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC36213, 3110059I09Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    centrosomal protein 15
    Names
    centrosomal protein 15 kDa
    uncharacterized protein C3orf14 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001284383.1 → NP_001271312.1  centrosomal protein 15 isoform 2

      See identical proteins and their annotated locations for NP_001271312.1

      Status: VALIDATED

      Source sequence(s)
      AC154682, AI931548, AK076182, AK078647, AV151510, BY233185
      Consensus CDS
      CCDS26817.1
      UniProtKB/Swiss-Prot
      Q6PFA6, Q8BGD0, Q8R061
      UniProtKB/TrEMBL
      A0A286YD67
      Related
      ENSMUSP00000153287.2, ENSMUST00000223762.2
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    2. NM_001284384.1 → NP_001271313.1  centrosomal protein 15 isoform 2

      See identical proteins and their annotated locations for NP_001271313.1

      Status: VALIDATED

      Source sequence(s)
      AC154682, AI931548, AK076182, AK078647, AV151510, BY073949, BY233185
      Consensus CDS
      CCDS26817.1
      UniProtKB/Swiss-Prot
      Q6PFA6, Q8BGD0, Q8R061
      UniProtKB/TrEMBL
      A0A286YD67
      Related
      ENSMUSP00000153430.2, ENSMUST00000224389.2
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    3. NM_001284385.1 → NP_001271314.1  centrosomal protein 15 isoform 2

      See identical proteins and their annotated locations for NP_001271314.1

      Status: VALIDATED

      Source sequence(s)
      AC154682, AK076182, AK078647, AV151510, BY073949
      Consensus CDS
      CCDS26817.1
      UniProtKB/Swiss-Prot
      Q6PFA6, Q8BGD0, Q8R061
      UniProtKB/TrEMBL
      A0A286YD67
      Related
      ENSMUSP00000153402.2, ENSMUST00000225294.2
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    4. NM_001284386.1 → NP_001271315.1  centrosomal protein 15 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154682, AK076182, AK078647, AV151510
      UniProtKB/Swiss-Prot
      Q8BGD0
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 86
      DUF4570; Domain of unknown function (DUF4570)

    5. NM_001284387.1 → NP_001271316.1  centrosomal protein 15 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC154682, AK076182, AK078647, AV151510, BE624571
      UniProtKB/TrEMBL
      A0A286YDP6
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 86
      DUF4570; Domain of unknown function (DUF4570)

    6. NM_001379567.1 → NP_001366496.1  centrosomal protein 15 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC154682
      UniProtKB/TrEMBL
      A0A286YDP6
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    7. NM_001379568.1 → NP_001366497.1  centrosomal protein 15 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC154682
      UniProtKB/TrEMBL
      A0A286YDP6
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    8. NM_001379569.1 → NP_001366498.1  centrosomal protein 15 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154682
      UniProtKB/Swiss-Prot
      Q6PFA6, Q8BGD0, Q8R061
      UniProtKB/TrEMBL
      A0A286YD67
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    9. NM_146051.3 → NP_666163.1  centrosomal protein 15 isoform 1

      See identical proteins and their annotated locations for NP_666163.1

      Status: VALIDATED

      Source sequence(s)
      AC154682, AK076182, AK078647, AV151510
      Consensus CDS
      CCDS36805.1
      UniProtKB/Swiss-Prot
      Q8BGD0
      Related
      ENSMUSP00000108288.4, ENSMUST00000112669.10
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 84
      DUF4570; Domain of unknown function (DUF4570)

    10. NM_178141.3 → NP_835277.1  centrosomal protein 15 isoform 2

      See identical proteins and their annotated locations for NP_835277.1

      Status: VALIDATED

      Source sequence(s)
      AC154682, AK076182, AK078647, AV151510
      Consensus CDS
      CCDS26817.1
      UniProtKB/Swiss-Prot
      Q6PFA6, Q8BGD0, Q8R061
      UniProtKB/TrEMBL
      A0A286YD67
      Related
      ENSMUSP00000126960.2, ENSMUST00000163392.3
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      10147278..10185610 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517987.5 → XP_006518050.1  centrosomal protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006518050.1

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    2. XM_006517989.5 → XP_006518052.1  centrosomal protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006518052.1

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    3. XM_006517995.4 → XP_006518058.1  centrosomal protein 15 isoform X4

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 87
      DUF4570; Domain of unknown function (DUF4570)

    4. XM_006517988.5 → XP_006518051.1  centrosomal protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006518051.1

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    5. XM_006517991.5 → XP_006518054.1  centrosomal protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006518054.1

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    6. XM_006517990.5 → XP_006518053.1  centrosomal protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006518053.1

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    7. XM_036158545.1 → XP_036014438.1  centrosomal protein 15 isoform X5

      Conserved Domains (1) summary
      pfam15134
      Location:36 → 86
      DUF4570; Domain of unknown function (DUF4570)

    8. XM_030247731.2 → XP_030103591.1  centrosomal protein 15 isoform X2

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    9. XM_036158546.1 → XP_036014439.1  centrosomal protein 15 isoform X6

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    10. XM_036158543.1 → XP_036014436.1  centrosomal protein 15 isoform X2

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    11. XM_006517997.2 → XP_006518060.1  centrosomal protein 15 isoform X6

      See identical proteins and their annotated locations for XP_006518060.1

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    12. XM_006517992.2 → XP_006518055.1  centrosomal protein 15 isoform X2

      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    13. XM_006517993.3 → XP_006518056.1  centrosomal protein 15 isoform X3

      See identical proteins and their annotated locations for XP_006518056.1

      UniProtKB/TrEMBL
      A0A286YDP6
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    14. XM_030247732.1 → XP_030103592.1  centrosomal protein 15 isoform X3

      UniProtKB/TrEMBL
      A0A286YDP6
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    15. XM_036158544.1 → XP_036014437.1  centrosomal protein 15 isoform X3

      UniProtKB/TrEMBL
      A0A286YDP6
      Related
      ENSMUSP00000153330.2, ENSMUST00000223702.2
      Conserved Domains (1) summary
      pfam15134
      Location:1 → 110
      DUF4570; Domain of unknown function (DUF4570)

    RNA

    1. XR_874030.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BGD0.1 GenPept UniProtKB/Swiss-Prot:Q8BGD0

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