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    MRPS12 putative mitochondrial 37S ribosomal protein MRPS12 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855772, updated on 2-Nov-2024

    Summary

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    Official Symbol
    MRPS12
    Official Full Name
    putative mitochondrial 37S ribosomal protein MRPS12
    Primary source
    SGD:S000005319
    Locus tag
    YNR036C
    See related
    AllianceGenome:SGD:S000005319; FungiDB:YNR036C; VEuPathDB:YNR036C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uS12m
    Summary
    A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial small ribosomal subunit. Used to study dilated cardiomyopathy. Orthologous to human MRPS12 (mitochondrial ribosomal protein S12). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See MRPS12 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (694361..694822, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Ego4p Neighboring gene Arc35p Neighboring gene mitochondrial 37S ribosomal protein RSM19 Neighboring gene putative ATP-dependent RNA helicase DBP6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cross-genomic analysis of the translational systems of various organisms. Fujita K, et al. J Ind Microbiol Biotechnol, 2001 Sep. PMID 11780787
    2. Adaptation, chance, and history in experimental evolution reversals to unicellularity. Rebolleda-Gómez M, et al. Evolution, 2019 Jan. PMID 30520011, Free PMC Article
    3. Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis. Suhm T, et al. Cell Metab, 2018 Jun 5. PMID 29754951
    4. Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components. Gan X, et al. Eur J Biochem, 2002 Nov. PMID 12392552
    5. Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Fleischer TC, et al. Genes Dev, 2006 May 15. PMID 16702403, Free PMC Article

    See all (46) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mitochondrial translation ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitochondrial small ribosomal subunit ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative mitochondrial 37S ribosomal protein MRPS12
    NP_014434.1
    • Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      694361..694822 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183213.1 → NP_014434.1  TPA: putative mitochondrial 37S ribosomal protein MRPS12 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014434.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1L2, P53732
      UniProtKB/TrEMBL
      A6ZSB1, B3LPK6, C7GLM0, G2WL94, N1NWU4
      Conserved Domains (1) summary
      TIGR00981
      Location:28 → 152
      rpsL_bact; ribosomal protein S12, bacterial/organelle
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53732.1

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