FEX2 fluoride transporter [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: FEX2
Official Full Name: fluoride transporter
Primary source: SGD:S000006200
Locus tag: YPL279C
See related: AllianceGenome:SGD:S000006200; FungiDB:YPL279C; VEuPathDB:YPL279C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables fluoride transmembrane transporter activity. Involved in fluoride transmembrane transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome XVI - NC_001148.4 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts.
Title: Engineered fluoride sensitivity enables biocontainment and selection of genetically-modified yeasts.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables fluoride transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables fluoride transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables fluoride transmembrane transporter activity	IGI Inferred from Genetic Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in fluoride transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in fluoride transmembrane transport	IGI Inferred from Genetic Interaction more info	PubMed
involved_in fluoride transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cell periphery	HDA more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

NP_015044.1

Protein involved in fluoride export; nearly identical to FEX1, and deletion of both proteins results in a large increase in fluoride sensitivity compared with the single mutant; contains two FEX domains connected by a linker; part of a widespread family of conserved fluoride export proteins

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The following sections contain reference sequences that belong to a specific genome build. Explain