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    TTN titin [ Phyllostomus discolor (pale spear-nosed bat) ]

    Gene ID: 114495427, updated on 30-Mar-2024

    Summary

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    Gene symbol
    TTN
    Gene description
    titin
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Phyllostomus discolor
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Phyllostominae; Phyllostomus
    Also known as
    ttn6
    Orthologs
    human mouse all
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    Genomic context

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    See TTN in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    313
    Annotation release Status Assembly Chr Location
    101 current mPhyDis1.pri.v3 (GCF_004126475.2) 4 NC_040906.2 (45443878..45714264)
    100 previous assembly mPhyDis1_v1.p (GCF_004126475.1) 4 NC_040906.1 (45446308..45714074)

    Chromosome 4 - NC_040906.2Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 141 Neighboring gene uncharacterized LOC118500065 Neighboring gene uncharacterized LOC118500064 Neighboring gene cysteine and glycine-rich protein 2-like Neighboring gene uncharacterized LOC118500066 Neighboring gene uncharacterized LOC118500067 Neighboring gene pleckstrin homology domain containing A3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: titin
    Names
    titin 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Phyllostomus discolor Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mPhyDis1.pri.v3

    Genomic

    1. NC_040906.2 Reference mPhyDis1.pri.v3

      Range
      45443878..45714264
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036023238.1 → XP_035879131.1  LOW QUALITY PROTEIN: titin

      UniProtKB/TrEMBL
      A0A7E6DJ81, A0A834AT90
      Conserved Domains (21) summary
      cd05747
      Location:32585 → 32676
      IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
      PTZ00121
      Location:9251 → 9730
      PTZ00121; MAEBL; Provisional
      smart00060
      Location:15525 → 15609
      FN3; Fibronectin type 3 domain
      smart00409
      Location:11341 → 11405
      IG; Immunoglobulin
      PHA03247
      Location:250 → 348
      PHA03247; large tegument protein UL36; Provisional
      COG0810
      Location:10304 → 10376
      TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
      cd00063
      Location:21682 → 21774
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14104
      Location:31277 → 31553
      STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
      pfam02818
      Location:10036 → 10062
      PPAK; PPAK motif
      pfam07679
      Location:6267 → 6356
      I-set; Immunoglobulin I-set domain
      pfam09042
      Location:643 → 682
      Titin_Z; Titin Z
      pfam13927
      Location:11248 → 11316
      Ig_3; Immunoglobulin domain
      pfam18362
      Location:8574 → 8604
      THB; Tri-helix bundle domain
      cd00096
      Location:18228 → 18230
      Ig; Ig strand A [structural motif]
      cd05748
      Location:20812 → 20891
      Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
      cd20927
      Location:31596 → 31685
      IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
      cd20951
      Location:2074 → 2165
      IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
      cd20972
      Location:103 → 193
      IgI_2_Titin_Z1z2-like; Second Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk, and similar domains; a member of the I-set of IgSF domains
      cd20974
      Location:6 → 98
      IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
      NF033839
      Location:10341 → 10805
      PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
      cl11960
      Location:18228 → 18321
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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