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    mt:ND6 mitochondrial NADH-ubiquinone oxidoreductase chain 6 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 19893555, updated on 2-Nov-2024

    Summary

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    Official Symbol
    mt:ND6provided by FlyBase
    Official Full Name
    mitochondrial NADH-ubiquinone oxidoreductase chain 6provided by FlyBase
    Primary source
    FLYBASE:FBgn0013685
    Locus tag
    Dmel_CG34089
    See related
    AllianceGenome:FB:FBgn0013685
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    mt:ND6; ND6
    Summary
    Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Part of respiratory chain complex I. Is expressed in adult head. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See mt:ND6 in Genome Data Viewer
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) MT (non-nuclear) NC_024511.2 (9971..10495)

    Chromosome MT - NC_024511.2Genomic Context describing neighboring genes Neighboring gene mitochondrial transfer RNA:Threonine-TGT Neighboring gene mitochondrial transfer RNA:Proline-TGG Neighboring gene mitochondrial Cytochrome b Neighboring gene mitochondrial transfer RNA:Serine-TGA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_024511.2 Chromosome MT Reference Release 6 plus ISO1 MT non-nuclear

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biogeography of Drosophila (Diptera: Drosophilidae) in East and Southeast Asia. Liu FG, et al. J Insect Sci, 2015. PMID 26078303, Free PMC Article
    2. Conservation of sequences of subunits of mitochondrial complex I and their relationships with other proteins. Fearnley IM, et al. Biochim Biophys Acta, 1992 Dec 7. PMID 1445936
    3. Extensive paternal mtDNA leakage in natural populations of Drosophila melanogaster. Nunes MD, et al. Mol Ecol, 2013 Apr. PMID 23452233, Free PMC Article
    4. Review: can diet influence the selective advantage of mitochondrial DNA haplotypes? Ballard JW, et al. Biosci Rep, 2015 Nov 5. PMID 26543031, Free PMC Article
    5. Variation in mitochondrial DNA affects locomotor activity and sleep in Drosophila melanogaster. Anderson L, et al. Heredity (Edinb), 2022 Oct. PMID 35764697, Free PMC Article

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables NADH dehydrogenase (ubiquinone) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of respiratory chain complex I IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADH dehydrogenase subunit 6
    YP_009047276.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_024511.2 Reference assembly

      Range
      9971..10495
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_009047276.1 Peptide Sequence

      See identical proteins and their annotated locations for YP_009047276.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P18933, Q7HM97
      UniProtKB/TrEMBL
      A0A1S6KXC2, B6E0Q2, J7FNN7
      Related
      FBpp0100185
      Conserved Domains (1) summary
      MTH00166
      Location:3 → 174
      ND6; NADH dehydrogenase subunit 6; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P18933.1 P18933

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