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    BDLF3 envelope glycoprotein 150 [ Human gammaherpesvirus 4 (Epstein-Barr virus) ]

    Gene ID: 3783694, updated on 18-Aug-2023

    Summary

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    Gene symbol
    BDLF3
    Gene description
    envelope glycoprotein 150
    Locus tag
    HHV4_BDLF3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Human gammaherpesvirus 4 (strain: B95-8, strain: Raji, type: 1, common: Epstein-Barr virus, acronym: EBV, acronym: HHV-4, nat-host: Homo sapiens)
    Lineage
    Viruses; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus
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    Genomic context

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    Sequence:
    NC_007605.1 (118066..118816, complement)

    NC_007605.1Genomic Context describing neighboring genes Neighboring gene tegument protein UL14 Neighboring gene deoxyribonuclease Neighboring gene tegument serine/threonine protein kinase Neighboring gene protein UL95 Neighboring gene myristylated tegument protein Neighboring gene DNA packaging terminase subunit 1 Neighboring gene protein UL91 Neighboring gene DNA packaging tegument protein UL17 Neighboring gene protein UL92 Neighboring gene tegument protein UL16 Neighboring gene envelope glycoprotein 48 Neighboring gene capsid triplex subunit 2 Neighboring gene major capsid protein Neighboring gene protein UL87 Neighboring gene tegument protein UL88 Neighboring gene envelope glycoprotein H Neighboring gene thymidine kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007605.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Missing Link in Epstein-Barr Virus Immune Evasion: the BDLF3 Gene Induces Ubiquitination and Downregulation of Major Histocompatibility Complex Class I (MHC-I) and MHC-II. Quinn LL, et al. J Virol, 2016 Jan 1. PMID 26468525, Free PMC Article
    2. Updated Epstein-Barr virus (EBV) DNA sequence and analysis of a promoter for the BART (CST, BARF0) RNAs of EBV. de Jesus O, et al. J Gen Virol, 2003 Jun. PMID 12771413
    3. The EB virus genome in Daudi Burkitt's lymphoma cells has a deletion similar to that observed in a non-transforming strain (P3HR-1) of the virus. Jones MD, et al. EMBO J, 1984 Apr. PMID 6327290, Free PMC Article
    4. Organization of the Epstein-Barr virus DNA molecule. III. Location of the P3HR-1 deletion junction and characterization of the NotI repeat units that form part of the template for an abundant 12-O-tetradecanoylphorbol-13-acetate-induced mRNA transcript. Jeang KT, et al. J Virol, 1983 Oct. PMID 6310141, Free PMC Article
    5. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Baer R, et al. Nature, 1984 Jul 19-25. PMID 6087149

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BDLF3 both enhanced internalization of surface major histocompatibility complex molecules and reduced the rate of their appearance at the cell surface.
      Title: The Missing Link in Epstein-Barr Virus Immune Evasion: the BDLF3 Gene Induces Ubiquitination and Downregulation of Major Histocompatibility Complex Class I (MHC-I) and MHC-II.
    Submit: New GeneRIF Correction

    General gene information

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    regulatory

    • Loc: c118071-118066 regulatory_class = polyA_signal_sequence
    • Loc: c118816-118811 regulatory_class = TATA_box

    General protein information

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    Preferred Names
    envelope glycoprotein 150

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007605.1 Reference assembly

      Range
      118066..118816 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_401694.1 envelope glycoprotein 150 [Human gammaherpesvirus 4]

      See identical proteins and their annotated locations for YP_401694.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P03224, Q777C5
      UniProtKB/TrEMBL
      A0A0B6VHP3, A0A4D6U0D2
      Conserved Domains (1) summary
      PHA03255
      Location:1 → 234
      PHA03255; BDLF3; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    2115423A.1

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