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    BCO2 beta-carotene oxygenase 2 [ Mustela putorius furo (domestic ferret) ]

    Gene ID: 101670802, updated on 16-Nov-2023

    Summary

    Gene symbol
    BCO2
    Gene description
    beta-carotene oxygenase 2
    See related
    Ensembl:ENSMPUG00000003697
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mustela putorius furo (sub-species: furo)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
    Also known as
    CMO; TEX12
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    Genomic context

    See BCO2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025421311.1 (8812889..8921921)
    101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569168.1 (1701841..1751187)

    NW_025421311.1Genomic Context describing neighboring genes Neighboring gene translocase of inner mitochondrial membrane 8 homolog B Neighboring gene succinate dehydrogenase complex subunit D Neighboring gene interleukin 18 Neighboring gene 6-pyruvoyltetrahydropterin synthase Neighboring gene placenta expressed transcript 1

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables beta-carotene 15,15'-dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables carotenoid dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in carotene catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in retinal metabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    carotenoid-cleaving dioxygenase, mitochondrial; beta,beta-carotene 9',10'-oxygenase
    Names
    carotene-9',10'-monooxygenase
    testis expressed 12
    NP_001297121.1
    XP_044933406.1
    XP_044933407.1
    XP_044933408.1
    XP_044933409.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310192.1NP_001297121.1  carotenoid-cleaving dioxygenase, mitochondrial

      See identical proteins and their annotated locations for NP_001297121.1

      Status: PROVISIONAL

      Source sequence(s)
      AY527150
      UniProtKB/Swiss-Prot
      Q6QT07
      UniProtKB/TrEMBL
      M1EJV8
      Conserved Domains (1) summary
      pfam03055
      Location:28540
      RPE65; Retinal pigment epithelial membrane protein

    RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1176430v1.1 Primary Assembly

    Genomic

    1. NW_025421311.1 Reference ASM1176430v1.1 Primary Assembly

      Range
      8812889..8921921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_045077473.1XP_044933408.1  beta,beta-carotene 9',10'-oxygenase isoform X2

      UniProtKB/TrEMBL
      A0A8U0RZU5, M1EJV8
      Conserved Domains (2) summary
      pfam15219
      Location:2862
      TEX12; Testis-expressed 12
      cl10080
      Location:101604
      RPE65; Retinal pigment epithelial membrane protein
    2. XM_045077474.1XP_044933409.1  beta,beta-carotene 9',10'-oxygenase isoform X3

      UniProtKB/TrEMBL
      A0A8U0UYI0, M1EJV8
      Conserved Domains (1) summary
      cl10080
      Location:38541
      RPE65; Retinal pigment epithelial membrane protein
    3. XM_045077471.1XP_044933406.1  beta,beta-carotene 9',10'-oxygenase isoform X1

      UniProtKB/TrEMBL
      A0A8U0S185
      Conserved Domains (2) summary
      pfam15219
      Location:113147
      TEX12; Testis-expressed 12
      cl10080
      Location:186689
      RPE65; Retinal pigment epithelial membrane protein
    4. XM_045077472.1XP_044933407.1  beta,beta-carotene 9',10'-oxygenase isoform X2

      UniProtKB/TrEMBL
      A0A8U0RZU5, M1EJV8
      Conserved Domains (2) summary
      pfam15219
      Location:2862
      TEX12; Testis-expressed 12
      cl10080
      Location:101604
      RPE65; Retinal pigment epithelial membrane protein