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    DEFA1B defensin alpha 1B [ Colobus angolensis palliatus ]

    Gene ID: 105525761, updated on 13-Mar-2024

    Summary

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    Gene symbol
    DEFA1B
    Gene description
    defensin alpha 1B
    See related
    Ensembl:ENSCANG00000041663
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Colobus angolensis palliatus (sub-species: palliatus)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Colobus
    Orthologs
    human all
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    Genomic context

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    See DEFA1B in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    100 current Cang.pa_1.0 (GCF_000951035.1) Unplaced Scaffold NW_012119143.1 (599176..601625, complement)

    NW_012119143.1Genomic Context describing neighboring genes Neighboring gene theta defensin subunit C Neighboring gene theta defensin subunit C Neighboring gene myosin phosphatase Rho-interacting protein-like Neighboring gene neutrophil defensin 4-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_012119143.1 Unplaced Scaffold Reference Cang.pa_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in antibacterial humoral response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-negative bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in defense response to Gram-positive bacterium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in disruption of plasma membrane integrity in another organism IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response in mucosa IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neutrophil defensin 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Colobus angolensis palliatus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Cang.pa_1.0

    Genomic

    1. NW_012119143.1 Reference Cang.pa_1.0

      Range
      599176..601625 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011961506.1 → XP_011816896.1  neutrophil defensin 1 isoform X1

      Conserved Domains (2) summary
      pfam00323
      Location:73 → 101
      Defensin_1; Mammalian defensin
      pfam00879
      Location:8 → 59
      Defensin_propep; Defensin propeptide

    2. XM_011961507.1 → XP_011816897.1  neutrophil defensin 1 isoform X2

      UniProtKB/TrEMBL
      A0A2K5K499
      Related
      ENSCANP00000035931.1, ENSCANT00000059177.1
      Conserved Domains (2) summary
      pfam00323
      Location:66 → 94
      Defensin_1; Mammalian defensin
      pfam00879
      Location:1 → 52
      Defensin_propep; Defensin propeptide
    Nucleotide Protein
    Heading Accession and Version

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