U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    Cnpy1 canopy FGF signaling regulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 269637, updated on 28-Oct-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Cnpy1provided by MGI
    Official Full Name
    canopy FGF signaling regulator 1provided by MGI
    Primary source
    MGI:MGI:2442451
    See related
    Ensembl:ENSMUSG00000044681 AllianceGenome:MGI:2442451
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500012D20Rik; 9630008K15Rik
    Summary
    Is expressed in several structures, including brain and olfactory epithelium. Orthologous to human CNPY1 (canopy FGF signaling regulator 1). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 59.1), CNS E11.5 (RPKM 25.1) and 3 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Cnpy1 in Genome Data Viewer
    Location:
    5 B1; 5 13.99 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (28405817..28450786, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (28200819..28245788, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42242 Neighboring gene predicted gene, 35395 Neighboring gene STARR-seq mESC enhancer starr_12715 Neighboring gene STARR-seq mESC enhancer starr_12716 Neighboring gene predicted gene, 35524 Neighboring gene predicted gene, 35602 Neighboring gene RNA binding motif protein 33

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Developmentally regulated Shh expression is robust to TAD perturbations. Williamson I, et al. Development, 2019 Sep 30. PMID 31511252, Free PMC Article
    2. Mapping the Shh long-range regulatory domain. Anderson E, et al. Development, 2014 Oct. PMID 25252942, Free PMC Article
    3. Increased β-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics. Paek H, et al. Dev Dyn, 2012 Feb. PMID 22102609, Free PMC Article
    4. Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation. He Y, et al. Aging Cell, 2021 Jul. PMID 34174788, Free PMC Article
    5. FGF regulated gene-expression and neuronal differentiation in the developing midbrain-hindbrain region. Jukkola T, et al. Dev Biol, 2006 Sep 1. PMID 16782087

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protein canopy homolog 1
    Names
    canopy 1 homolog

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310511.1 → NP_001297440.1  protein canopy homolog 1

      See identical proteins and their annotated locations for NP_001297440.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC129184, AK139155, AK162570, BX630527
      Consensus CDS
      CCDS80237.1
      UniProtKB/Swiss-Prot
      Q4VAB4, Q8CBK9
      Related
      ENSMUSP00000113944.2, ENSMUST00000118882.2
      Conserved Domains (1) summary
      pfam11938
      Location:2 → 78
      DUF3456; TLR4 regulator and MIR-interacting MSAP

    2. NM_001310512.1 → NP_001297441.1  protein canopy homolog 1

      See identical proteins and their annotated locations for NP_001297441.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC129184, AK035938, BX630527
      Consensus CDS
      CCDS80237.1
      UniProtKB/Swiss-Prot
      Q4VAB4, Q8CBK9
      Conserved Domains (1) summary
      pfam11938
      Location:2 → 78
      DUF3456; TLR4 regulator and MIR-interacting MSAP

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      28405817..28450786 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175651.4: Suppressed sequence

      Description
      NM_175651.4: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4VAB4.1 GenPept UniProtKB/Swiss-Prot:Q4VAB4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools