U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    LIP1 lipase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816012, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    LIP1
    Official Full Name
    lipase 1
    Primary source
    TAIR:AT2G15230
    Locus tag
    AT2G15230
    See related
    Araport:AT2G15230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATLIP1; F15A23.3; F15A23_3; lipase 1
    Summary
    Lipase active on medium and short chain triacylglycerols, but not on phospho- or galactolipids. Active between pH4 and 7 with an optimum at pH6. Knock-out mutant has not obvious phenotype. Predicted to be extracellular.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See LIP1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (6612480..6615457)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Plant basic secretory protein (BSP) family protein Neighboring gene ncRNA Neighboring gene UNC-50 family protein Neighboring gene pseudo Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification and characterization of a triacylglycerol lipase in Arabidopsis homologous to mammalian acid lipases. El-Kouhen K, et al. FEBS Lett, 2005 Nov 7. PMID 16226259
    2. Arabidopsis DELLA and two HD-ZIP transcription factors regulate GA signaling in the epidermis through the L1 box cis-element. Rombolá-Caldentey B, et al. Plant Cell, 2014 Jul. PMID 24989044, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    NM_127084.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables galactolipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables phospholipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables triacylglycerol lipase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycerolipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of seed dormancy process IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of seed germination IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to gibberellin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in extracellular space TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    lipase 1
    NP_179126.2
    • lipase 1 (LIP1); CONTAINS InterPro DOMAIN/s: AB-hydrolase-associated lipase region (InterPro:IPR006693), Alpha/beta hydrolase fold-1 (InterPro:IPR000073); BEST Arabidopsis thaliana protein match is: Myzus persicae-induced lipase 1 (TAIR:AT5G14180.1); Has 1912 Blast hits to 1877 proteins in 247 species: Archae - 0; Bacteria - 112; Metazoa - 1231; Fungi - 287; Plants - 167; Viruses - 0; Other Eukaryotes - 115 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6612480..6615457
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127084.3 → NP_179126.2  lipase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179126.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1H5B7, Q71DJ5, Q9SKL5
      UniProtKB/TrEMBL
      A0A5S9WY84, A0A654ET12
      Conserved Domains (1) summary
      PLN02872
      Location:6 → 393
      PLN02872; triacylglycerol lipase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q71DJ5.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools