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    l(2)efl lethal (2) essential for life [ Musca domestica (house fly) ]

    Gene ID: 101896196, updated on 22-Jun-2024

    Summary

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    Gene symbol
    l(2)efl
    Gene description
    lethal (2) essential for life
    See related
    VectorBase:MDOMA2_002141
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Musca domestica
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea; Muscidae; Musca
    Also known as
    hsp20
    Orthologs
    fruit fly all
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    Genomic context

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    See l(2)efl in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_08 current Musca_domestica.polishedcontigs.V.1.1 (GCF_030504385.1) Unplaced Scaffold NW_026712115.1 (13765693..13773568, complement)
    102 previous assembly Musca_domestica-2.0.2 (GCF_000371365.1) Unplaced Scaffold NW_004769827.1 (24066..31004)

    NW_026712115.1Genomic Context describing neighboring genes Neighboring gene high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 Neighboring gene uncharacterized LOC131804237 Neighboring gene sulfotransferase 1 family member D1 Neighboring gene uncharacterized LOC131804590 Neighboring gene uncharacterized LOC131804271

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein refolding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to heat IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lethal (2) essential for life; protein lethal(2)essential for life
    Names
    Hsp20/alpha crystallin family
    heat shock protein 20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001308969.1 → NP_001295898.1  lethal (2) essential for life

      See identical proteins and their annotated locations for NP_001295898.1

      Status: PROVISIONAL

      Source sequence(s)
      KF974799
      UniProtKB/TrEMBL
      W8GVN7
      Conserved Domains (2) summary
      cd06526
      Location:72 → 154
      metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
      COG0071
      Location:77 → 169
      IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]

    RefSeqs of Annotated Genomes: GCF_030504385.1-RS_2023_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Musca_domestica.polishedcontigs.V.1.1 Primary Assembly

    Genomic

    1. NW_026712115.1 Reference Musca_domestica.polishedcontigs.V.1.1 Primary Assembly

      Range
      13765693..13773568 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005190902.4 → XP_005190959.1  protein lethal(2)essential for life isoform X1

      See identical proteins and their annotated locations for XP_005190959.1

      UniProtKB/TrEMBL
      T1P922
      Conserved Domains (2) summary
      cd06526
      Location:72 → 154
      metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
      COG0071
      Location:77 → 169
      IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]

    2. XM_011297323.3 → XP_011295625.1  protein lethal(2)essential for life isoform X1

      See identical proteins and their annotated locations for XP_011295625.1

      UniProtKB/TrEMBL
      T1P922
      Conserved Domains (2) summary
      cd06526
      Location:72 → 154
      metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
      COG0071
      Location:77 → 169
      IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]

    3. XM_005190903.4 → XP_005190960.1  protein lethal(2)essential for life isoform X1

      See identical proteins and their annotated locations for XP_005190960.1

      UniProtKB/TrEMBL
      T1P922
      Conserved Domains (2) summary
      cd06526
      Location:72 → 154
      metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
      COG0071
      Location:77 → 169
      IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]

    4. XM_011297324.3 → XP_011295626.1  protein lethal(2)essential for life isoform X1

      See identical proteins and their annotated locations for XP_011295626.1

      UniProtKB/TrEMBL
      T1P922
      Conserved Domains (2) summary
      cd06526
      Location:72 → 154
      metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
      COG0071
      Location:77 → 169
      IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein Strain
    Heading Accession and Version

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