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    putative methyltransferase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855042, updated on 2-Nov-2024

    Summary

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    Official Full Name
    putative methyltransferase
    Primary source
    SGD:S000004629
    Locus tag
    YMR027W
    See related
    AllianceGenome:SGD:S000004629; FungiDB:YMR027W; VEuPathDB:YMR027W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables phosphatase activity. Predicted to be involved in DNA damage response. Located in cytoplasm and nucleus. Orthologous to human ARMT1 (acidic residue methyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (325877..327289)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Csi1p Neighboring gene ubiquitin-protein ligase peroxin 12 Neighboring gene Tap42p Neighboring gene Far8p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Virus-like particles of the Ty3 retrotransposon assemble in association with P-body components. Beliakova-Bethell N, et al. RNA, 2006 Jan. PMID 16373495, Free PMC Article
    2. Investigation by atomic force microscopy of the structure of Ty3 retrotransposon particles. Kuznetsov YG, et al. J Virol, 2005 Jul. PMID 15956549, Free PMC Article
    3. Regulation of lipid droplet dynamics in Saccharomyces cerevisiae depends on the Rab7-like Ypt7p, HOPS complex and V1-ATPase. Bouchez I, et al. Biol Open, 2015 May 6. PMID 25948753, Free PMC Article
    4. Cross-compartment signal propagation in the mitotic exit network. Zhou X, et al. Elife, 2021 Jan 22. PMID 33481703, Free PMC Article
    5. A family of metal-dependent phosphatases implicated in metabolite damage-control. Huang L, et al. Nat Chem Biol, 2016 Aug. PMID 27322068, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables fructose 6-phosphate aldolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fructose-1-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    putative methyltransferase
    NP_013740.1
    • A metal-dependent phosphatase, part of the DUF89 protein family; dephosphorylates fructose-1-phosphate; human ortholog, C6orf211 is involved in response to DNA damage; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      325877..327289
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182523.1 → NP_013740.1  TPA: putative methyltransferase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013740.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZK1, Q04371
      UniProtKB/TrEMBL
      C7GL92, G2WK78, N1NY73
      Conserved Domains (1) summary
      pfam01937
      Location:19 → 438
      DUF89; Protein of unknown function DUF89
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q04371.1

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