| SIRT1, a target of miR-708-3p, alleviates fluoride-induced neuronal damage via remodeling mitochondrial network dynamics. | SIRT1, a target of miR-708-3p, alleviates fluoride-induced neuronal damage via remodeling mitochondrial network dynamics.
Zhao Q, Zhou GY, Niu Q, Chen JW, Li P, Tian ZY, Li DJ, Xia T, Zhang S, Wang AG., Free PMC Article | 10/21/2024 |
| MiR-708 regulates the biological behavior of childhood leukemia cells by binding to the 3'utr end of the target gene and reducing the level of the target gene. | MiR-708 regulates the biological behavior of childhood leukemia cells by binding to the 3'utr end of the target gene and reducing the level of the target gene.
Li Y, Zhang Y, Guan L. | 06/1/2023 |
| MicroRNA-708 emerges as a potential candidate to target undruggable NRAS. | MicroRNA-708 emerges as a potential candidate to target undruggable NRAS.
Pang JM, Chien PC, Kao MC, Chiu PY, Chen PX, Hsu YL, Liu C, Liang X, Lin KT., Free PMC Article | 05/8/2023 |
| MicroRNA-708 suppresses the proliferation, migration, and invasion of human retinoblastoma cells by targeting RAP2B, a member of the RAS oncogene family. | MicroRNA-708 suppresses the proliferation, migration, and invasion of human retinoblastoma cells by targeting RAP2B, a member of the RAS oncogene family.
Dai C, Yu H, Bai Q, Huang D, Li J, Wang W. | 01/14/2023 |
| The Double Face of miR-708: A Pan-Cancer Player with Dissociative Identity Disorder. | The Double Face of miR-708: A Pan-Cancer Player with Dissociative Identity Disorder.
Carvalho de Oliveira J, Mathias C, Oliveira VC, Pezuk JA, Brassesco MS., Free PMC Article | 01/11/2023 |
| The Transcription Factor TFCP2L1 is Associated with Myelination via miR708-5p Regulation in the Peripheral Nerve System. | The Transcription Factor TFCP2L1 is Associated with Myelination via miR708-5p Regulation in the Peripheral Nerve System.
Sohn EJ, Nam YK. | 04/9/2022 |
| Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells. | Functional characterization of miR-708 microRNA in telomerase positive and negative human cancer cells.
Kaul Z, Cheung CTY, Bhargava P, Sari AN, Yu Y, Huifu H, Bid H, Henson JD, Groden J, Reddel RR, Kaul SC, Wadhwa R., Free PMC Article | 11/6/2021 |
| Synergistic effects of miR-708-5p and miR-708-3p accelerate the progression of osteoporosis. | Synergistic effects of miR-708-5p and miR-708-3p accelerate the progression of osteoporosis.
Wang R, Feng Y, Xu H, Huang H, Zhao S, Wang Y, Li H, Cao J, Xu G, Huang S., Free PMC Article | 06/26/2021 |
| MicroRNA-708 modulates Hepatic Stellate Cells activation and enhances extracellular matrix accumulation via direct targeting TMEM88. | MicroRNA-708 modulates Hepatic Stellate Cells activation and enhances extracellular matrix accumulation via direct targeting TMEM88.
Xu T, Pan L, Li L, Hu S, Zhou H, Yang C, Yang J, Li H, Liu Y, Meng X, Li J., Free PMC Article | 05/1/2021 |
| Long non-coding RNA MINCR aggravates colon cancer via regulating miR-708-5p-mediated Wnt/beta-catenin pathway. | Long non-coding RNA MINCR aggravates colon cancer via regulating miR-708-5p-mediated Wnt/β-catenin pathway.
Yu Y, Chang Z, Han C, Zhuang L, Zhou C, Qi X, Peng Z. | 02/27/2021 |
| MicroRNA-708 represses hepatic stellate cells activation and proliferation by targeting ZEB1 through Wnt/beta-catenin pathway. | MicroRNA-708 represses hepatic stellate cells activation and proliferation by targeting ZEB1 through Wnt/β-catenin pathway.
Yang J, Tao Q, Zhou Y, Chen Q, Li L, Hu S, Liu Y, Zhang Y, Shu J, Zhang X, Zhang L, Zhang L. | 11/28/2020 |
| MicroRNA-708-5p regulates mycobacterial vitality and the secretion of inflammatory factors in Mycobacterium tuberculosis-infected macrophages by targeting TLR4. | MicroRNA-708-5p regulates mycobacterial vitality and the secretion of inflammatory factors in Mycobacterium tuberculosis-infected macrophages by targeting TLR4.
Li WT, Zhang Q. | 10/10/2020 |
| MicroRNA-708 prevents ethanol-induced hepatic lipid accumulation and inflammatory reaction via direct targeting ZEB1. | MicroRNA-708 prevents ethanol-induced hepatic lipid accumulation and inflammatory reaction via direct targeting ZEB1.
Hu S, Liu YM, Chen-Chen, Li LY, Zhang BY, Yang JF, Li HD, Meng XM, Jun-Li, Xu T, Zhou H. | 10/10/2020 |
| MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells. | MicroRNA-708 is a novel regulator of the Hoxa9 program in myeloid cells.
Schneider E, Pochert N, Ruess C, MacPhee L, Escano L, Miller C, Krowiorz K, Delsing Malmberg E, Heravi-Moussavi A, Lorzadeh A, Ashouri A, Grasedieck S, Sperb N, Kumar Kopparapu P, Iben S, Staffas A, Xiang P, Rösler R, Kanduri M, Larsson E, Fogelstrand L, Döhner H, Döhner K, Wiese S, Hirst M, Keith Humphries R, Palmqvist L, Kuchenbauer F, Rouhi A. | 10/3/2020 |
| Metformin mediates induction of miR-708 to inhibit self-renewal and chemoresistance of breast cancer stem cells through targeting CD47. | Metformin mediates induction of miR-708 to inhibit self-renewal and chemoresistance of breast cancer stem cells through targeting CD47.
Tan W, Tang H, Jiang X, Ye F, Huang L, Shi D, Li L, Huang X, Li L, Xie X, Xie X., Free PMC Article | 08/29/2020 |
| The microRNA7085p/ZEB1/EMT axis mediates the metastatic potential of osteosarcoma. | The microRNA‑708‑5p/ZEB1/EMT axis mediates the metastatic potential of osteosarcoma.
Feng T, Zhu Z, Jin Y, Wang H, Mao X, Liu D, Li Y, Lu L, Zuo G., Free PMC Article | 08/22/2020 |
| miR-708 inhibited AKT/beta-catenin signaling, which is activated by SPHK2. In addition, miR-708 was transcriptionally repressed by EZH2 (enhancer of zeste homolog 2)-induced histone H3 lysine 27 trimethylation and promoter methylation. In summary, these findings revealed that miR-708 is a glioma tumor suppressor. | Silencing of microRNA-708 promotes cell growth and epithelial-to-mesenchymal transition by activating the SPHK2/AKT/β-catenin pathway in glioma.
Chen Y, Deng X, Chen W, Shi P, Lian M, Wang H, Wang K, Qian D, Xiao D, Long H., Free PMC Article | 07/18/2020 |
| In vivo, miR708-NP directly targeted the SOX2/OCT4-mCherry+ miR-708(low) tumor cells to impair metastasis. Together, our preclinical findings provide a mechanism-based antimetastatic therapeutic approach for Triple-negative breast cancer (TNBC), with a marked potential to generate miR-708 replacement therapy for high-risk TNBC patients in the clinic. | Nanoparticle Delivery of miR-708 Mimetic Impairs Breast Cancer Metastasis.
Ramchandani D, Lee SK, Yomtoubian S, Han MS, Tung CH, Mittal V., Free PMC Article | 03/14/2020 |
| that LOXL1-AS1/miR-708-5p/USF1 pathway contributed to the development of gastric cancer | LncRNA LOXL1-AS1 facilitates the tumorigenesis and stemness of gastric carcinoma via regulation of miR-708-5p/USF1 pathway.
Sun Q, Li J, Li F, Li H, Bei S, Zhang X, Feng L., Free PMC Article | 12/21/2019 |
| GR agonists induced miR-708 and downstream suppression of NF-kappaB signaling. | MicroRNA-708 activation by glucocorticoid receptor agonists regulate breast cancer tumorigenesis and metastasis via downregulation of NF-κB signaling.
Senthil Kumar KJ, Gokila Vani M, Hsieh HW, Lin CC, Liao JW, Chueh PJ, Wang SY. | 12/7/2019 |
| MiRNA-708 expression was reduced in osteosarcoma tumor cell lines. | MiRNA-708/CUL4B axis contributes into cell proliferation and apoptosis of osteosarcoma.
Chen G, Zhou H. | 11/16/2019 |
| MiR-708-5p suppresses NSCLC initiation, development, and stemness through interfering DNMT3A-dependent DNA methylation. | Downregulation of DNMT3A by miR-708-5p Inhibits Lung Cancer Stem Cell-like Phenotypes through Repressing Wnt/β-catenin Signaling.
Liu T, Wu X, Chen T, Luo Z, Hu X. | 09/28/2019 |
| CA inhibits the proliferation and invasion of CML KBM-7 cells which could mainly be due to downregulation of microRNA- 780 expression. | Carnosic acid regulates cell proliferation and invasion in chronic myeloid leukemia cancer cells via suppressing microRNA-708.
Liu D, Wang B, Zhu Y, Yan F, Dong W. | 08/17/2019 |
| We found that miRNA-708-5p was upregulated in pancreatic ductal adenocarcinoma tissues and cell lines, and high miRNA-708 expression indicated poor prognosis in pancreatic ductal adenocarcinoma patients. | MiR-708-5p inhibits the progression of pancreatic ductal adenocarcinoma by targeting Sirt3.
Huang S, Guo H, Cao Y, Xiong J. | 06/15/2019 |
| Despite being downregulated in Ewing sarcoma tissue samples, miR-708-5p might represent a secondary genetic alteration derived from the pleiotropic cellular effects of the abnormal EWS/FLI1 transcription factor that does not affect tumor growth but instead, is related with the promotion of tumor invasion. | MiR-708-5p is inversely associated with EWS/FLI1 Ewing sarcoma but does not represent a prognostic predictor.
Roberto GM, Vieira GM, Delsin LEA, Silva MO, Hakime RG, Engel EE, Scrideli CA, Tone LG, Brassesco MS. | 06/1/2019 |