Pokemon inhibits Bim transcription to promote the proliferation, anti-anoikis, invasion, histological grade, and dukes stage of colorectal neoplasms. | Pokemon inhibits Bim transcription to promote the proliferation, anti-anoikis, invasion, histological grade, and dukes stage of colorectal neoplasms. Wang Y, Zeng H, Li L, Liu J, Lin J, Bie Y, Wang S, Cheng X, Nashun B, Yao Y, Hu X, Zhao Y., Free PMC Article | 08/6/2024 |
Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy. | Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy. Zhang Q, Wu Q, Huan XJ, Song SS, Bao XB, Miao ZH, Wang YQ. | 04/25/2024 |
Coexpression of TP53, BIM, and PTEN Enhances the Therapeutic Efficacy of Non-Small-Cell Lung Cancer. | Coexpression of TP53, BIM, and PTEN Enhances the Therapeutic Efficacy of Non-Small-Cell Lung Cancer. Lu L, Ma D, Xi Z. | 02/15/2024 |
Protein interaction networks characterizing the A549 cells Klotho transfected are associated with activated pro-apoptotic Bim and suppressed Wnt/beta-catenin signaling pathway. | Protein interaction networks characterizing the A549 cells Klotho transfected are associated with activated pro-apoptotic Bim and suppressed Wnt/β-catenin signaling pathway. Matsumoto M, Ogawa N, Fukuda T, Bando Y, Nishimura T, Usuda J., Free PMC Article | 02/5/2024 |
Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis. | Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis. Lambrecht R, Rudolf F, Ückert AK, Sladky VC, Phan TS, Jansen J, Naim S, Kaufmann T, Keogh A, Kirschnek S, Mangerich A, Stengel F, Leist M, Villunger A, Brunner T., Free PMC Article | 01/12/2024 |
Expression Levels of MicroRNA-300/BCL2L11 in Papillary Thyroid Cancer and Their Clinical Diagnostic Values. | Expression Levels of MicroRNA-300/BCL2L11 in Papillary Thyroid Cancer and Their Clinical Diagnostic Values. Shen Y, Li X, Xie R, Chen Y, Hu X, Liu Y, Ma H. | 09/7/2023 |
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity. | Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity. Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J. | 05/17/2023 |
miR-24-3p down-regulates the expression of the apoptotic factors FasL and BIM in human natural killer cells. | miR-24-3p down-regulates the expression of the apoptotic factors FasL and BIM in human natural killer cells. Regis S, Dondero A, Spaggiari GM, Serra M, Caliendo F, Bottino C, Castriconi R. | 09/10/2022 |
MicroRNA-17-5p Protects against Propofol Anesthesia-Induced Neurotoxicity and Autophagy Impairment via Targeting BCL2L11. | MicroRNA-17-5p Protects against Propofol Anesthesia-Induced Neurotoxicity and Autophagy Impairment via Targeting BCL2L11. Xiu M, Luan H, Gu X, Liu C, Xu D., Free PMC Article | 07/16/2022 |
Significant role of long non-coding RNA MALAT1 in deep vein thrombosis via the regulation of vascular endothelial cell physiology through the microRNA-383-5p/BCL2L11 axis. | Significant role of long non-coding RNA MALAT1 in deep vein thrombosis via the regulation of vascular endothelial cell physiology through the microRNA-383-5p/BCL2L11 axis. Wang H, Lin S, Yang Y, Zhao M, Li X, Zhang L., Free PMC Article | 06/25/2022 |
EGFR Inhibitors Plus Bevacizumab are Superior Than EGFR Inhibitors Alone as First-Line Setting in Advanced NSCLC With EGFR Mutations and BIM Deletion Polymorphisms (BIM-CLICaP). | EGFR Inhibitors Plus Bevacizumab are Superior Than EGFR Inhibitors Alone as First-Line Setting in Advanced NSCLC With EGFR Mutations and BIM Deletion Polymorphisms (BIM-CLICaP). Cardona AF, Ordóñez-Reyes C, Ruiz-Patiño A, Garcia-Robledo JE, Barron LZ, Recondo G, Rojas L, Corrales L, Martín C, Barrón F, Sotelo C, Rodríguez J, Ricaurte L, Rolfo C, Ávila J, Mayorga D, Archila P, Otero J, Mas L, Bermudez M, Gamez T, Carranza H, Vargas C, Rosell R, Arrieta O. | 03/26/2022 |
FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation. | FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation. Zhu R, Li L, Nguyen B, Seo J, Wu M, Seale T, Levis M, Duffield A, Hu Y, Small D., Free PMC Article | 03/26/2022 |
Prognostic Value of BIM Deletion in EGFR-Mutant NSCLC Patients Treated with EGFR-TKIs: A Meta-Analysis. | Prognostic Value of BIM Deletion in EGFR-Mutant NSCLC Patients Treated with EGFR-TKIs: A Meta-Analysis. Lv F, Sun L, Yang Q, Pan Z, Zhang Y., Free PMC Article | 01/29/2022 |
Melatonin induces apoptotic cell death through Bim stabilization by Sp1-mediated OTUD1 upregulation. | Melatonin induces apoptotic cell death through Bim stabilization by Sp1-mediated OTUD1 upregulation. Woo SM, Seo SU, Min KJ, Kwon TK. | 01/22/2022 |
[Effect of U2AF1 Mutation to Inflammatory Cytokine Expression in SKM-1 Cells through FOXO3a-Bim Signaling Pathway]. | [Effect of U2AF1 Mutation to Inflammatory Cytokine Expression in SKM-1 Cells through FOXO3a-Bim Signaling Pathway]. Zhu YQ, Wu LY. | 12/18/2021 |
Bim's Effect on the Expression of miR-423-3p in Promoting Primary Hepatic Cancer (PHC) and Role of miR-423-3p in PHC Proliferation and Invasion. | Bim's Effect on the Expression of miR-423-3p in Promoting Primary Hepatic Cancer (PHC) and Role of miR-423-3p in PHC Proliferation and Invasion. Liu Z, Cui Y. | 10/2/2021 |
Genetic variants in human BCL2L11 (BIM) are associated with ulcerative forms of Buruli ulcer. | Genetic variants in human BCL2L11 (BIM) are associated with ulcerative forms of Buruli ulcer. Fevereiro J, Fraga AG, Capela C, Sopoh GE, Dossou A, Ayelo GA, Peixoto MJ, Cunha C, Carvalho A, Rodrigues F, Pedrosa J., Free PMC Article | 08/21/2021 |
Efficacy of EGFR tyrosine kinase inhibitors in patients having EGFR-activating mutations with or without BIM polymorphisms. | Efficacy of EGFR tyrosine kinase inhibitors in patients having EGFR-activating mutations with or without BIM polymorphisms. Ariyasu R, Yanagitani N, Tadokoro K, Yamaguchi T, Uchibori K, Kitazono S, Fujita N, Katayama R, Nishio M. | 05/22/2021 |
Renal tubular Bim mediates the tubule-podocyte crosstalk via NFAT2 to induce podocyte cytoskeletal dysfunction. | Renal tubular Bim mediates the tubule-podocyte crosstalk via NFAT2 to induce podocyte cytoskeletal dysfunction. Xu C, Zhou X, Xie T, Zhou Y, Zhang Q, Jiang S, Zhang R, Liao L, Dong J., Free PMC Article | 05/22/2021 |
MicroRNA253p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim. | MicroRNA‑25‑3p regulates human nucleus pulposus cell proliferation and apoptosis in intervertebral disc degeneration by targeting Bim. Zhao Z, Zheng J, Ye Y, Zhao K, Wang R, Wang R., Free PMC Article | 05/1/2021 |
Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells. | Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells. Cai Z, Aguilera F, Ramdas B, Daulatabad SV, Srivastava R, Kotzin JJ, Carroll M, Wertheim G, Williams A, Janga SC, Zhang C, Henao-Mejia J, Kapur R., Free PMC Article | 05/1/2021 |
Glucocorticoids can induce BIM to trigger apoptosis in the absence of BAX and BAK1. | Glucocorticoids can induce BIM to trigger apoptosis in the absence of BAX and BAK1. Dong L, Vaux DL., Free PMC Article | 04/17/2021 |
The pro-apoptotic domain of BIM protein forms toxic amyloid fibrils. | The pro-apoptotic domain of BIM protein forms toxic amyloid fibrils. Malishev R, Ben-Zichri S, Oren O, Shauloff N, Peretz T, Taube R, Papo N, Jelinek R., Free PMC Article | 04/3/2021 |
miR-885 mediated cardioprotection against hypoxia/reoxygenation-induced apoptosis in human cardiomyocytes via inhibition of PTEN and BCL2L11 and modulation of AKT/mTOR signaling. | miR-885 mediated cardioprotection against hypoxia/reoxygenation-induced apoptosis in human cardiomyocytes via inhibition of PTEN and BCL2L11 and modulation of AKT/mTOR signaling. Meng X, Mei L, Zhao C, Chen W, Zhang N. | 03/13/2021 |
Clinical significance of BIM deletion polymorphism in chemoradiotherapy for non-small cell lung cancer. | Clinical significance of BIM deletion polymorphism in chemoradiotherapy for non-small cell lung cancer. Wakabayashi Y, Masuda T, Fujitaka K, Nakashima T, Okumoto J, Shimoji K, Nishimura Y, Yamaguchi K, Sakamoto S, Horimasu Y, Miyamoto S, Iwamoto H, Ohshimo S, Hamada H, Hattori N., Free PMC Article | 03/6/2021 |