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    CASC11 cancer susceptibility 11 [ Homo sapiens (human) ]

    Gene ID: 100270680, updated on 17-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    LncRNA CASC11 upregulation promotes HDAC4 to alleviate oxidized low-density lipoprotein-induced injury of cardiac microvascular endothelial cells.

    LncRNA CASC11 upregulation promotes HDAC4 to alleviate oxidized low-density lipoprotein-induced injury of cardiac microvascular endothelial cells.
    Hu K, Huang MJ, Ling S, Li YX, Cao XY, Chen YF, Lei JM, Fu WZ, Tan BF.

    08/16/2023
    Correlation between plasma lncRNA CASC11 and malignancy in lung adenocarcinoma patients and the prognostic value of lncRNA CASC11.

    Correlation between plasma lncRNA CASC11 and malignancy in lung adenocarcinoma patients and the prognostic value of lncRNA CASC11.
    Gu X, Zhang Y, Xiong H.

    08/7/2023
    LncRNA MYMLR promotes pituitary adenoma development by upregulating carbonyl reductase 1 via sponging miR-197-3p.

    LncRNA MYMLR promotes pituitary adenoma development by upregulating carbonyl reductase 1 via sponging miR-197-3p.
    Wang T, Mao P, Zhang Y, Cui B, Wang MD, Li Y, Gao K.

    10/22/2022
    Long noncoding RNA CASC11 interacts with YBX1 to promote prostate cancer progression by suppressing the p53 pathway.

    Long non‑coding RNA CASC11 interacts with YBX1 to promote prostate cancer progression by suppressing the p53 pathway.
    Sun X, Xin S, Zhang Y, Jin L, Liu X, Zhang J, Mei W, Zhang B, Ma W, Ye L., Free PMC Article

    08/6/2022
    CASC11 promotes aggressiveness of prostate cancer cells through miR-145/IGF1R axis.

    CASC11 promotes aggressiveness of prostate cancer cells through miR-145/IGF1R axis.
    Capik O, Sanli F, Kurt A, Ceylan O, Suer I, Kaya M, Ittmann M, Karatas OF.

    02/5/2022
    [Role of LncRNA CASC11 in the malignant transformation of 16HBE cells induced by glycidyl methacrylate].

    [Role of LncRNA CASC11 in the malignant transformation of 16HBE cells induced by glycidyl methacrylate].
    Wang M, Wang Q, Ma S, Li X, Wuhan B, Xu J.

    01/1/2022
    Contribution of lncRNA CASC8, CASC11, and PVT1 Genetic Variants to the Susceptibility of Coronary Heart Disease.

    Contribution of lncRNA CASC8, CASC11, and PVT1 Genetic Variants to the Susceptibility of Coronary Heart Disease.
    Lu Y, Yuan W, Wang L, Ning M, Han Y, Gu W, Zhao T, Shang F, Guo X.

    12/18/2021
    Silencing CASC11 curbs neonatal neuroblastoma progression through modulating microRNA-676-3p/nucleolar protein 4 like (NOL4L) axis.

    Silencing CASC11 curbs neonatal neuroblastoma progression through modulating microRNA-676-3p/nucleolar protein 4 like (NOL4L) axis.
    Yu Z, Zhang J, Han J.

    04/13/2021
    LncRNA CASC11 was downregulated in coronary artery disease and inhibits transforming growth factor-beta1.

    LncRNA CASC11 was downregulated in coronary artery disease and inhibits transforming growth factor-β1.
    Chen J, Dang J., Free PMC Article

    01/9/2021
    LncRNA CASC11 promotes the development of esophageal carcinoma by regulating KLF6.

    LncRNA CASC11 promotes the development of esophageal carcinoma by regulating KLF6.
    Chen SG, Wang CH, He RQ, Xu RY, Ji CB.

    10/10/2020
    LncRNA CASC11 promotes the development of lung cancer through targeting microRNA-302/CDK1 axis.

    LncRNA CASC11 promotes the development of lung cancer through targeting microRNA-302/CDK1 axis.
    Tong W, Han TC, Wang W, Zhao J.

    10/3/2020
    lncRNA CASC11 promotes cancer cell proliferation in bladder cancer through miRNA-150.

    lncRNA CASC11 promotes cancer cell proliferation in bladder cancer through miRNA-150.
    Luo H, Xu C, Le W, Ge B, Wang T., Free PMC Article

    08/15/2020
    Interactions of PVT1 and CASC11 on Prostate Cancer Risk in African Americans.

    Interactions of PVT1 and CASC11 on Prostate Cancer Risk in African Americans.
    Lin HY, Callan CY, Fang Z, Tung HY, Park JY., Free PMC Article

    08/13/2020
    The CASC11 was shown to target the miR-498/FOXO3 axis via a canonical competing endogenous RNA (ceRNA).

    The positive feedback loop FOXO3/CASC11/miR-498 promotes the tumorigenesis of non-small cell lung cancer.
    Yan R, Jiang Y, Lai B, Lin Y, Wen J.

    07/4/2020
    High levels of CASC11 in the hepatocellular carcinoma tissues were significantly correlated with poor survival.CASC11 regulates miR-188-5p expression in the hepatocellular carcinoma.

    LncRNA CASC11 promotes cancer cell proliferation in hepatocellular carcinoma by inhibiting miRNA-188-5p.
    Cheng N, Wu J, Yin M, Xu J, Wang Y, Chen X, Nie Z, Yin J., Free PMC Article

    06/20/2020
    the miR-498 was found to target the 3'-UTR of lncRNA CASC11 and FOXK1 mRNA.

    SP1 induced lncRNA CASC11 accelerates the glioma tumorigenesis through targeting FOXK1 via sponging miR-498.
    Jin J, Zhang S, Hu Y, Zhang Y, Guo C, Feng F.

    01/11/2020
    CASC11 is upregulated in POP and is correlated with TNF-alpha.

    LncRNA CASC11 is upregulated in postmenopausal osteoporosis and is correlated with TNF-α.
    Yu H, Zhou W, Yan W, Xu Z, Xie Y, Zhang P., Free PMC Article

    01/4/2020
    MYMLR was identified to maintain MYC transcriptional activity and cell cycle progression despite low levels of expression. A proteomic search for MYMLR-binding proteins identified PCBP2, while it was also found that MYMLR places a 557-kb upstream enhancer region in the proximity of the MYC promoter in cooperation with PCBP2. These findings implicate a crucial role for MYMLR in regulation MYC oncogene.

    Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter-enhancer interaction.
    Kajino T, Shimamura T, Gong S, Yanagisawa K, Ida L, Nakatochi M, Griesing S, Shimada Y, Kano K, Suzuki M, Miyano S, Takahashi T., Free PMC Article

    12/28/2019
    CASC11 may improve atherosclerosis by downregulating IL-9 and regulating VSMC apoptosis and proliferation

    LncRNA CASC11 improves atherosclerosis by downregulating IL-9 and regulating vascular smooth muscle cell apoptosis and proliferation.
    Tao K, Hu Z, Zhang Y, Jiang D, Cheng H.

    08/10/2019
    CASC11 is upregulated in ovarian squamous cell carcinoma (OSCC), and overexpression of CASC11 in OSCC mediated the development of cancer cell resistance to chemotherapy.

    Overexpression of CASC11 in ovarian squamous cell carcinoma mediates the development of cancer cell resistance to chemotherapy.
    Shen F, Feng L, Zhou J, Zhang H, Xu Y, Jiang R, Zhang H, Chen Y.

    07/27/2019
    lncRNA CASC11 promotes TGF-beta1, increases cancer cell stemness and predicts postoperative survival in small cell lung cancer.

    LncRNA CASC11 promotes TGF-β1, increases cancer cell stemness and predicts postoperative survival in small cell lung cancer.
    Fu Y, Zhang P, Nan H, Lu Y, Zhao J, Yang M, Song Q.

    06/22/2019
    CASC11 epigenetically silenced PTEN by binding with EZH2 in hepatocellular carcinoma cells

    STAT3-induced upregulation of lncRNA CASC11 promotes the cell migration, invasion and epithelial-mesenchymal transition in hepatocellular carcinoma by epigenetically silencing PTEN and activating PI3K/AKT signaling pathway.
    Han Y, Chen M, Wang A, Fan X.

    06/8/2019
    CASC11 can target heterogeneous ribonucleoprotein K (hnRNP-K) to activate WNT/beta-catenin signaling in colorectal cancer cells to promote tumor growth and metastasis.

    Long non-coding RNA CASC11 interacts with hnRNP-K and activates the WNT/β-catenin pathway to promote growth and metastasis in colorectal cancer.
    Zhang Z, Zhou C, Chang Y, Zhang Z, Hu Y, Zhang F, Lu Y, Zheng L, Zhang W, Li X, Li X.

    02/18/2017
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