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    MIR1228 microRNA 1228 [ Homo sapiens (human) ]

    Gene ID: 100302201, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Exosomal miR-1228-5p down-regulates DUSP22 to promotes cell proliferation and migration in small cell lung cancer.

    Exosomal miR-1228-5p down-regulates DUSP22 to promotes cell proliferation and migration in small cell lung cancer.
    Mu X, Yu C, Zhao Y, Hu X, Wang H, He Y, Wu H.

    07/8/2024
    Extracellular vesicles derived from cancer-associated fibroblasts carry tumor-promotive microRNA-1228-3p to enhance the resistance of hepatocellular carcinoma cells to sorafenib.

    Extracellular vesicles derived from cancer-associated fibroblasts carry tumor-promotive microRNA-1228-3p to enhance the resistance of hepatocellular carcinoma cells to sorafenib.
    Zhang Y, Pan Q, Shao Z.

    01/14/2023
    Ultrasound-Targeted Microbubble Destruction-Mediated miR-1228 Downregulation Suppresses Tumor Proliferation, Migration, and Invasion of Cervical-Cancer Cells.

    Ultrasound-Targeted Microbubble Destruction-Mediated miR-1228 Downregulation Suppresses Tumor Proliferation, Migration, and Invasion of Cervical-Cancer Cells.
    Bu Y, Li Q, Liang X, Gao Q, Ma X, Jin M, Yang X.

    10/15/2022
    CircRAB3B suppresses proliferation, motility, cell cycle progression and promotes the apoptosis of IL-22-induced keratinocytes depending on the regulation of miR-1228-3p/PTEN axis in psoriasis.

    CircRAB3B suppresses proliferation, motility, cell cycle progression and promotes the apoptosis of IL-22-induced keratinocytes depending on the regulation of miR-1228-3p/PTEN axis in psoriasis.
    Lu J, Xu X, Li Y, Yu N, Ding Y, Shi Y.

    04/2/2022
    CircGFRA1 facilitates the malignant progression of HER-2-positive breast cancer via acting as a sponge of miR-1228 and enhancing AIFM2 expression.

    CircGFRA1 facilitates the malignant progression of HER-2-positive breast cancer via acting as a sponge of miR-1228 and enhancing AIFM2 expression.
    Bazhabayi M, Qiu X, Li X, Yang A, Wen W, Zhang X, Xiao X, He R, Liu P., Free PMC Article

    03/19/2022
    MicroRNA 1228 Mediates the Viability of High Glucose-Cultured Renal Tubule Cells through Targeting Thrombospondin 2 and PI3K/AKT Signaling Pathway.

    MicroRNA 1228 Mediates the Viability of High Glucose-Cultured Renal Tubule Cells through Targeting Thrombospondin 2 and PI3K/AKT Signaling Pathway.
    Mo T, Fu Q, Hu X, Fu Y, Li J.

    02/5/2022
    Hsa_circ_0000301 facilitates the progression of cervical cancer by targeting miR-1228-3p/IRF4 Axis.

    Hsa_circ_0000301 facilitates the progression of cervical cancer by targeting miR-1228-3p/IRF4 Axis.
    Deng ZM, Dai FF, Zhou Q, Cheng YX., Free PMC Article

    10/23/2021
    Plasma-Derived Exosomal hsa-miR-4488 and hsa-miR-1228-5p: Novel Biomarkers for Dermatomyositis-Associated Interstitial Lung Disease with Anti-Melanoma Differentiation-Associated Protein 5 Antibody-Positive Subset.

    Plasma-Derived Exosomal hsa-miR-4488 and hsa-miR-1228-5p: Novel Biomarkers for Dermatomyositis-Associated Interstitial Lung Disease with Anti-Melanoma Differentiation-Associated Protein 5 Antibody-Positive Subset.
    Zhong D, Wu C, Xu D, Bai J, Wang Q, Zeng X., Free PMC Article

    09/25/2021
    Circ_0004417 inhibits the progression of prostate cancer through sponging miR-1228.

    Circ_0004417 inhibits the progression of prostate cancer through sponging miR-1228.
    Xia HY, Liu CD, Liang W, Huo XY, Wei XW.

    09/18/2021
    Circulating microRNA-194 and microRNA-1228 Could Predict Colon Cancer Proliferation via Phospho S6 Modulation.

    Circulating microRNA-194 and microRNA-1228 Could Predict Colon Cancer Proliferation via Phospho S6 Modulation.
    Pasca S, Ionescu C, Andras D, Eniu D, Muresan MA, Magdo L, Jurj A, Raduly L, Cojocneanu R, Petrushev B, Zaharie F, Irimie A, Berindan-Neagoe I, Muresan MS.

    08/28/2021
    Exosomes derived from miR-1228 overexpressing bone marrow-mesenchymal stem cells promote growth of gastric cancer cells.

    Exosomes derived from miR-1228 overexpressing bone marrow-mesenchymal stem cells promote growth of gastric cancer cells.
    Chang L, Gao H, Wang L, Wang N, Zhang S, Zhou X, Yang H., Free PMC Article

    07/31/2021
    Serum miR-1228-3p and miR-181a-5p as Noninvasive Biomarkers for Non-Small Cell Lung Cancer Diagnosis and Prognosis.

    Serum miR-1228-3p and miR-181a-5p as Noninvasive Biomarkers for Non-Small Cell Lung Cancer Diagnosis and Prognosis.
    Xue WX, Zhang MY, Rui Li, Liu X, Yin YH, Qu YQ., Free PMC Article

    04/24/2021
    Urinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of Kidney Fibrosis in Diabetic Nephropathy.

    Urinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of Kidney Fibrosis in Diabetic Nephropathy.
    Conserva F, Barozzino M, Pesce F, Divella C, Oranger A, Papale M, Sallustio F, Simone S, Laviola L, Giorgino F, Gallone A, Pontrelli P, Gesualdo L., Free PMC Article

    11/21/2020
    This study provides evidence that CAF exosomal miR-1228 is able to promote osteosarcoma invasion and migration by targeting SCAI.

    Exosomal miR-1228 From Cancer-Associated Fibroblasts Promotes Cell Migration and Invasion of Osteosarcoma by Directly Targeting SCAI.
    Wang JW, Wu XF, Gu XJ, Jiang XH., Free PMC Article

    03/21/2020
    hsa_circ_100395 regulates lung cancer cell proliferation, migration and invasion through modulating miR-1228/TCF21 pathway.

    CircRNA hsa_circ_100395 regulates miR-1228/TCF21 pathway to inhibit lung cancer progression.
    Chen D, Ma W, Ke Z, Xie F., Free PMC Article

    12/7/2019
    miR-1228 acts as a negative regulator of gastric cancer growth and angiogenesis through downregulation of migration inhibitory factor

    microRNA-1228(⁎) impairs the pro-angiogenic activity of gastric cancer cells by targeting macrophage migration inhibitory factor.
    Jia L, Chen J, Xie C, Shao L, Xu Z, Zhang L.

    07/1/2017
    Thus, our results demonstrate that PM2.5-induced A549 apoptosis is initiated by mitochondrial dysfunction and miR-1228-5p could protect A549 cells against apoptosis.

    MicroRNA-1228(*) inhibit apoptosis in A549 cells exposed to fine particulate matter.
    Li X, Ding Z, Zhang C, Zhang X, Meng Q, Wu S, Wang S, Yin L, Pu Y, Chen R.

    03/25/2017
    miR-1228 promoted breast cancer proliferation, invasion and migration was mediated by MOAP1 and SCAI.

    MiR-1228 promotes breast cancer cell growth and metastasis through targeting SCAI protein.
    Lin L, Liu D, Liang H, Xue L, Su C, Liu M., Free PMC Article

    06/11/2016
    TP53 downregulation leads to an increase in miR-1228 expression, forming a positive feedback loop that contributes to cancerogenesis in hepatoma.

    miR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop.
    Zhang Y, Dai J, Deng H, Wan H, Liu M, Wang J, Li S, Li X, Tang H., Free PMC Article

    03/21/2015
    Ingenuity Pathway Analysis showed miR-1228 to be involved extensively in metabolism-related signal pathways and organ morphology, implying that miR-1228 functions as a housekeeping gene.

    Human miR-1228 as a stable endogenous control for the quantification of circulating microRNAs in cancer patients.
    Hu J, Wang Z, Liao BY, Yu L, Gao X, Lu S, Wang S, Dai Z, Zhang X, Chen Q, Qiu SJ, Wu Y, Zhu H, Fan J, Zhou J, Wang J.

    08/16/2014
    Analysis of two potential targets for miR-637 and miR-1228 in HOB, type IV collagen (COL4A1) and bone morphogenic protein 2 kinase (BMP2K), respectively, showed that 1,25D-mediates suppression of these targets via distinct mechanisms

    Vitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblasts.
    Lisse TS, Chun RF, Rieger S, Adams JS, Hewison M., Free PMC Article

    12/14/2013
    miR-1228* negatively regulated NF-kappaB activity in SGC-7901 gastric cancer cells and found that CK2A2 was a target of miR-1228*. Upregulation of miR-1228* decreased the expression of mesenchymal markers and increased the epithelial marker

    Restoration of miR-1228* expression suppresses epithelial-mesenchymal transition in gastric cancer.
    Jia L, Wu J, Zhang L, Chen J, Zhong D, Xu S, Xie C, Cai J., Free PMC Article

    10/19/2013
    Enforced miR-1228 expression can reduce MOAP1 expression and delay the progression of stress-induced cell apoptosis.

    miR-1228 prevents cellular apoptosis through targeting of MOAP1 protein.
    Yan B, Zhao JL.

    12/22/2012
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