Platelet-rich plasma treatment alleviates osteoarthritis-related pain, inflammation, and apoptosis by upregulating the expression levels of microRNA-375 and microRNA-337. | Platelet-rich plasma treatment alleviates osteoarthritis-related pain, inflammation, and apoptosis by upregulating the expression levels of microRNA-375 and microRNA-337. Sun X, Mi L, Du G, Sun C, He S. | 03/19/2022 |
Role of microRNA3753pmediated regulation in tinnitus development. | Role of microRNA‑375‑3p‑mediated regulation in tinnitus development. Han KH, Cho H, Han KR, Mun SK, Kim YK, Park I, Chang M., Free PMC Article | 12/11/2021 |
MiR-375-3p mediates reduced pineal function in hypoxia-ischemia brain damage. | MiR-375-3p mediates reduced pineal function in hypoxia-ischemia brain damage. Xu L, Li G, Tang X, Feng C, Li M, Jiang X, Gu Y, Yun Y, Lu L, Feng X, Ding X, Sun B. | 12/11/2021 |
miR-375 induces adipogenesis through targeting Erk1 in pancreatic duct cells under the influence of sodium palmitate. | miR-375 induces adipogenesis through targeting Erk1 in pancreatic duct cells under the influence of sodium palmitate. Gezginci-Oktayoglu S, Sancar S, Karatug-Kacar A, Bolkent S. | 10/2/2021 |
miR-375-3p contributes to hypoxia-induced apoptosis by targeting forkhead box P1 (FOXP1) and Bcl2 like protein 2 (Bcl2l2) in rat cardiomyocyte h9c2 cells. | miR-375-3p contributes to hypoxia-induced apoptosis by targeting forkhead box P1 (FOXP1) and Bcl2 like protein 2 (Bcl2l2) in rat cardiomyocyte h9c2 cells. Li Y, Li X, Wang L, Han N, Yin G. | 09/11/2021 |
MiR-375-3p regulates rat pulmonary microvascular endothelial cell activity by targeting Notch1 during hypoxia. | MiR-375-3p regulates rat pulmonary microvascular endothelial cell activity by targeting Notch1 during hypoxia. An Y, Liu Z, Ding H, Lv Q, Fan H, Hou S, Cai W, Liu S., Free PMC Article | 04/13/2021 |
Relationship between miR-375 regulating Ndrg2/IL-6/STAT3 signaling pathway and diabetic retinopathy in rats. | Relationship between miR-375 regulating Ndrg2/IL-6/STAT3 signaling pathway and diabetic retinopathy in rats. Pu LJ, Chen W, Liu QH, Huang AP, Zhao Q, Gu HH. | 03/20/2021 |
miR-375-3p inhibitor suppresses Ang II-induced cardiomyocyte hypertrophy by promoting LDHB expression. | MicroRNA-375-3p inhibitor suppresses angiotensin II-induced cardiomyocyte hypertrophy by promoting lactate dehydrogenase B expression. Feng H, Wu J, Chen P, Wang J, Deng Y, Zhu G, Xian J, Huang L, Ouyang W. | 05/30/2020 |
miR-375 inhibits hepatocyte growth factor-elicited migration of mesenchymal stem cells through downregulating the expression of PDK1 and suppressing the activation of Akt. | MiR-375 inhibits the hepatocyte growth factor-elicited migration of mesenchymal stem cells by downregulating Akt signaling. He L, Wang X, Kang N, Xu J, Dai N, Xu X, Zhang H. | 12/29/2018 |
our findings showed that miR-375 binds to 3'-UTR region of Ctgf mRNA, subsequently leading to the decreased expression of Ctgf in the I/R brain. Furthermore, we showed that miR-375/Ctgf-mediated protective effects are associated with p21/PI3K/Akt signaling pathways. | MiR-375 attenuates injury of cerebral ischemia/reperfusion via targetting Ctgf. Ou J, Kou L, Liang L, Tang C., Free PMC Article | 08/18/2018 |
miR-375 has multiple functions with importance in the formation of pancreatic beta-cell identity, control of beta cell mass and regulation of insulin secretion. (Review) | The small RNA miR-375 - a pancreatic islet abundant miRNA with multiple roles in endocrine beta cell function. Eliasson L. | 05/19/2018 |
These novel findings suggest that miR-375 acts as a potent negative mediator in regulating the synthesis and secretion of CATs in the adrenal medulla during the maintenance of homeostasis under stress. | miR-375 negatively regulates the synthesis and secretion of catecholamines by targeting Sp1 in rat adrenal medulla. Gai Y, Zhang J, Wei C, Cao W, Cui Y, Cui S. | 08/26/2017 |
miR-217 and miR-375 represent promising biomarkers of pancreatic injury in rats | Serum microRNAs-217 and -375 as biomarkers of acute pancreatic injury in rats. Calvano J, Edwards G, Hixson C, Burr H, Mangipudy R, Tirmenstein M. | 05/13/2017 |
Down-regulation of miR-375 is associated with furan hepatotoxicity. | Irreversible down-regulation of miR-375 in the livers of Fischer 344 rats after chronic furan exposure. de Conti A, Tryndyak V, Doerge DR, Beland FA, Pogribny IP. | 03/4/2017 |
Our results demonstrated that NDRG2 promoted secreted miR-375 in microvesicles shed from M1 microglia, which induced neuron damage. | NDRG2 promoted secreted miR-375 in microvesicles shed from M1 microglia, which induced neuron damage. Tang LL, Wu YB, Fang CQ, Qu P, Gao ZL. | 05/28/2016 |
miR-375 regulates the canonical Wnt pathway through FZD8 silencing in arthritis synovial fibroblasts | miR-375 regulates the canonical Wnt pathway through FZD8 silencing in arthritis synovial fibroblasts. Miao CG, Shi WJ, Xiong YY, Yu H, Zhang XL, Qin MS, Du CL, Song TW, Li J. | 11/21/2015 |
Upregulation of miR-375 provides a protective effect on cerebral ischemia/reperfusion injury following calycosin administration. | Downregulated RASD1 and upregulated miR-375 are involved in protective effects of calycosin on cerebral ischemia/reperfusion rats. Wang Y, Dong X, Li Z, Wang W, Tian J, Chen J. | 12/20/2014 |
pancreatic failure after in utero malnutrition could result from transgenerational transmission of miRNA-375 misexpression in beta-cells. | Maternal protein restriction leads to pancreatic failure in offspring: role of misexpressed microRNA-375. Dumortier O, Hinault C, Gautier N, Patouraux S, Casamento V, Van Obberghen E. | 11/22/2014 |
The results provided evidence that miR-375 regulates alveolar epithelial trans-differentiation through the Wnt/beta-catenin pathway and identified FZD8 as one of the targets of miR-375. | miR-375 regulates rat alveolar epithelial cell trans-differentiation by inhibiting Wnt/β-catenin pathway. Wang Y, Huang C, Reddy Chintagari N, Bhaskaran M, Weng T, Guo Y, Xiao X, Liu L., Free PMC Article | 06/15/2013 |
analysis of transcriptional mechanisms controlling miR-375 gene expression in the pancreas | Transcriptional mechanisms controlling miR-375 gene expression in the pancreas. Avnit-Sagi T, Vana T, Walker MD., Free PMC Article | 10/13/2012 |
miR-375 negatively regulates insulin secretion, and attenuation of miR-375 through the cyclic AMP-protein kinase A pathway may boost the insulin response in pancreatic beta-cells. | Regulation of microRNA-375 by cAMP in pancreatic β-cells. Keller DM, Clark EA, Goodman RH., Free PMC Article | 09/22/2012 |
miR-7 is the most abundant endocrine miRNA in islets while miR-375 is the most abundant intra-islet miRNA. | Quantitative differential expression analysis reveals miR-7 as major islet microRNA. Bravo-Egana V, Rosero S, Molano RD, Pileggi A, Ricordi C, Domínguez-Bendala J, Pastori RL., Free PMC Article | 12/7/2011 |