| Interleukin-18 binding protein regulates the apoptosis and necroptosis of fibroblast-like synoviocytes and chondrocytes in rheumatoid arthritis. | Interleukin-18 binding protein regulates the apoptosis and necroptosis of fibroblast-like synoviocytes and chondrocytes in rheumatoid arthritis.
Min HK, Kim SH, Lee JY, Lee SH, Kim HR. | 11/16/2023 |
| Level of interleukin-18 binding protein is significantly different in patients with anaphylaxis than urticaria. | Level of interleukin-18 binding protein is significantly different in patients with anaphylaxis than urticaria.
Kim HS, Kim K, Lee H, Yang EA, Chun YH, Kim HH, Kim JT. | 02/11/2023 |
| Interleukin-18 and IL-18BP in inflammatory dermatological diseases. | Interleukin-18 and IL-18BP in inflammatory dermatological diseases.
Wang X, Wang L, Wen X, Zhang L, Jiang X, He G., Free PMC Article | 02/9/2023 |
| Caspase-1 and interleukin-18 in children with post infectious bronchiolitis obliterans: a case-control study. | Caspase-1 and interleukin-18 in children with post infectious bronchiolitis obliterans: a case-control study.
Şişmanlar Eyüboğlu T, Aslan AT, Ramaslı Gürsoy T, Pekcan S, Köse M, Hangül M, Aral LA, Bulut V. | 08/13/2022 |
| Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity. | Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity.
Detry S, Andries J, Bloch Y, Gabay C, Clancy DM, Savvides SN., Free PMC Article | 06/11/2022 |
| Balance between Interleukin-18 and Interleukin-18 binding protein in auto-inflammatory diseases. | Balance between Interleukin-18 and Interleukin-18 binding protein in auto-inflammatory diseases.
Harel M, Fauteux-Daniel S, Girard-Guyonvarc'h C, Gabay C. | 04/16/2022 |
| Interleukin-18 binding protein in infants and children hospitalized with pneumonia in low-resource settings. | Interleukin-18 binding protein in infants and children hospitalized with pneumonia in low-resource settings.
Konrad ER, Soo J, Conroy AL, Namasopo S, Opoka RO, Hawkes MT. | 04/16/2022 |
| IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritis. | IL-18 binding protein suppresses IL-17-induced osteoclastogenesis and rectifies type 17 helper T cell / regulatory T cell imbalance in rheumatoid arthritis.
Min HK, Kim S, Lee JY, Kim KW, Lee SH, Kim HR., Free PMC Article | 11/6/2021 |
| IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria. | IL-18 and IL-18 binding protein are related to disease severity and parasitemia during falciparum malaria.
Otterdal K, Berg A, Michelsen AE, Yndestad A, Patel S, Gregersen I, Halvorsen B, Ueland T, Langeland N, Aukrust P., Free PMC Article | 10/23/2021 |
| IL-18 and IL-18 binding protein concentration in ovarian follicular fluid of women with unexplained infertility to PCOS during in vitro fertilization. | IL-18 and IL-18 binding protein concentration in ovarian follicular fluid of women with unexplained infertility to PCOS during in vitro fertilization.
Zhang H, Wang X, Xu J, Zhu Y, Chen X, Hu Y. | 05/29/2021 |
| asthma is very likely to be determined by balance of IL-18/IL-18BP/IL-18R expression in inflammatory cells. | Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R.
Zhang H, Wang J, Wang L, Xie H, Chen L, He S., Free PMC Article | 02/9/2019 |
| these results were corroborated in female osteoporotic subjects where decreased serum IL-18BP levels and enhanced serum IL-18 levels were observed. Our study forms a strong basis for using humanized IL-18BP towards the treatment of postmenopausal osteoporosis. | IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation.
Mansoori MN, Shukla P, Kakaji M, Tyagi AM, Srivastava K, Shukla M, Dixit M, Kureel J, Gupta S, Singh D., Free PMC Article | 06/9/2018 |
| epigenetic silencing by single CpG methylation determines differential IL18BP inducibility in monocytic versus epithelial cells. T | Epigenetic regulation by CpG methylation splits strong from retarded IFNγ-induced IL-18BP in epithelial versus monocytic cells.
Bachmann M, Pfeilschifter J, Mühl H. | 06/2/2018 |
| a large proportion blood basophils from patients with asthma express IL-18 and IL-18BP. mast cells and basophils are implicated in the pathogenesis of asthma via an IL-18-related mechanism. | Altered expression of IL-18 binding protein and IL-18 receptor in basophils and mast cells of asthma patients.
Wang Z, Liu Z, Wang L, Wang J, Chen L, Xie H, Zhang H, He S. | 05/5/2018 |
| The maintenance of normal production of IL-18BP may contribute, at least in part, to the ability ofLong Term Non-Progressors to delay AIDS progression. | A potentially protective role of IL-18 Binding Protein in HIV-infected Long-Term Non-Progressors.
Iannello A, Samarani S, Allam O, Jenabian MA, Mehraj V, Amre D, Routy JP, Tremblay C, Ahmad A. | 01/6/2018 |
| Platelets also contain the IL-18 antagonist, the IL-18-Binding Protein (IL-18BP); however, it is not synthesized in them de novo, is present in pre-made form and is released irrespective of platelet activation. | Differential synthesis and release of IL-18 and IL-18 Binding Protein from human platelets and their implications for HIV infection.
Allam O, Samarani S, Jenabian MA, Routy JP, Tremblay C, Amre D, Ahmad A. | 01/6/2018 |
| The serum levels of IL-37, which were correlated with antibody production and the serum levels of total IL-18 and IL-18BP, were elevated in the patients with primary Sjogren's syndrome. | Elevated IL-37, IL-18 and IL-18BP serum concentrations in patients with primary Sjögren's syndrome.
Liuqing W, Liping X, Hui S, Jing L. | 12/23/2017 |
| an imbalance in the production of IL-18 and its antagonist (an increase in the production of IL-18 with a decrease, no increase or an insufficient increase in the production of IL-18BP) has been described in many chronic inflammatory diseases in humans. | Imbalanced production of IL-18 and its antagonist in human diseases, and its implications for HIV-1 infection.
Samarani S, Allam O, Sagala P, Aldabah Z, Jenabian MA, Mehraj V, Tremblay C, Routy JP, Amre D, Ahmad A. | 12/16/2017 |
| IL-18, IL-18R and IL-18BP expression in eosinophil are involved in the inflammatory reaction of asthma. | [Elevated IL-18, IL-18 binding protein and IL-18 receptor in eosinophil-enriched blood cells in patients with asthma].
Yuan L, Lu S, Zhang H, Wang J, Hu Y, Wang L, He S. | 09/16/2017 |
| the inhibition of IL-18 signaling by IL-18BPa may be involved in the development of pulmonary vascular involvement leading to pulmonary hypertension and modulate the systemic inflammation in systemic sclerosis | Serum levels of interleukin-18-binding protein isoform a: Clinical association with inflammation and pulmonary hypertension in systemic sclerosis.
Nakamura K, Asano Y, Taniguchi T, Minatsuki S, Inaba T, Maki H, Hatano M, Yamashita T, Saigusa R, Ichimura Y, Takahashi T, Toyama T, Yoshizaki A, Miyagaki T, Sugaya M, Sato S. | 05/27/2017 |
| The natural IL-18 inhibitor IL-18BP further regulates IL-18 activity in the extracellular environment. Review. | Context-dependent role of IL-18 in cancer biology and counter-regulation by IL-18BP.
Fabbi M, Carbotti G, Ferrini S. | 06/20/2015 |
| imbalance of IL-18/IL-18BP ratio in IgA nephropathy especially in patients with arteriolar lesions | Imbalance of interleukin-18 and interleukin-18 binding protein in patients with IgA nephropathy implicating renal vasculopathy.
Shimizu C, Matsumoto K, Fujita T, Fuke Y, Soma M. | 05/2/2015 |
| IL-18, IL-18BP, and IL-18R may have roles in the pathogenesis of epithelial ovarian carcinoma | Expression of IL-18, IL-18 binding protein, and IL-18 receptor by normal and cancerous human ovarian tissues: possible implication of IL-18 in the pathogenesis of ovarian carcinoma.
Medina L, Rabinovich A, Piura B, Dyomin V, Levy RS, Huleihel M., Free PMC Article | 02/14/2015 |
| HPV16 E7 oncoprotein increases production of the IL18BP in keratinocytes. | Human papillomavirus E7 oncoprotein increases production of the anti-inflammatory interleukin-18 binding protein in keratinocytes.
Richards KH, Doble R, Wasson CW, Haider M, Blair GE, Wittmann M, Macdonald A., Free PMC Article | 06/28/2014 |
| these data indicate that IL-18BP, which is produced in EOC in response to microenvironmental factors, may inhibit endogenous or exogenous IL-18 activity | The IL-18 antagonist IL-18-binding protein is produced in the human ovarian cancer microenvironment.
Carbotti G, Barisione G, Orengo AM, Brizzolara A, Airoldi I, Bagnoli M, Pinciroli P, Mezzanzanica D, Centurioni MG, Fabbi M, Ferrini S. | 06/21/2014 |