| DPP3 promotes breast cancer tumorigenesis by stabilizing FASN and promoting lipid synthesis. | DPP3 promotes breast cancer tumorigenesis by stabilizing FASN and promoting lipid synthesis.
Fu X, Li X, Wang W, Li J., Free PMC Article | 06/6/2024 |
| Dipeptidyl-peptidase 3 and IL-6: potential biomarkers for diagnostics in COVID-19 and association with pulmonary infiltrates. | Dipeptidyl-peptidase 3 and IL-6: potential biomarkers for diagnostics in COVID-19 and association with pulmonary infiltrates.
Staudner ST, Leininger SB, Vogel MJ, Mustroph J, Hubauer U, Meindl C, Wallner S, Lehn P, Burkhardt R, Hanses F, Zimmermann M, Scharf G, Hamer OW, Maier LS, Hupf J, Jungbauer CG., Free PMC Article | 12/23/2023 |
| Involvement of DPP3 in modulating oncological features and oxidative stress response in esophageal squamous cell carcinoma. | Involvement of DPP3 in modulating oncological features and oxidative stress response in esophageal squamous cell carcinoma.
Arora M, Kumari S, Kadian L, Anupa G, Singh J, Kumar A, Verma D, Pramanik R, Kumar S, Yadav R, Chopra A, Chauhan SS., Free PMC Article | 09/8/2023 |
| Identification of an Additional Metal-Binding Site in Human Dipeptidyl Peptidase III. | Identification of an Additional Metal-Binding Site in Human Dipeptidyl Peptidase III.
Matić A, Šupljika F, Brkić H, Jurasović J, Karačić Z, Tomić S., Free PMC Article | 08/30/2023 |
| The emerging role of dipeptidyl peptidase 3 in pathophysiology. | The emerging role of dipeptidyl peptidase 3 in pathophysiology.
Malovan G, Hierzberger B, Suraci S, Schaefer M, Santos K, Jha S, Macheroux P. | 05/7/2023 |
| A Novel Indicator of Myocardial Injury after Acute Myocardial Infarction: 'DPP-3'. | A Novel Indicator of Myocardial Injury after Acute Myocardial Infarction: 'DPP-3'.
Ozden O, Yesildas C, Demir M, Surmeli AO, Yesil E, Orscelik O, Celik A., Free PMC Article | 12/17/2022 |
| DPP3 expression promotes cell proliferation and migration in vitro and tumour growth in vivo, which is associated with poor prognosis of oesophageal carcinoma. | DPP3 expression promotes cell proliferation and migration in vitro and tumour growth in vivo, which is associated with poor prognosis of oesophageal carcinoma.
Liu JK, Abudula A, Yang HT, Xu LX, Nuerrula Y, Bai G, Tulahong A, Eli M., Free PMC Article | 12/10/2022 |
| Dipeptidyl Peptidase 3 Activity as a Promising Biomarker of Bone Fragility in Postmenopausal Women. | Dipeptidyl Peptidase 3 Activity as a Promising Biomarker of Bone Fragility in Postmenopausal Women.
Menale C, Tabacco G, Naciu AM, Schiavone ML, Cannata F, Morenghi E, Sobacchi C, Palermo A., Free PMC Article | 07/2/2022 |
| DPP3/CDK1 contributes to the progression of colorectal cancer through regulating cell proliferation, cell apoptosis, and cell migration. | DPP3/CDK1 contributes to the progression of colorectal cancer through regulating cell proliferation, cell apoptosis, and cell migration.
Tong Y, Huang Y, Zhang Y, Zeng X, Yan M, Xia Z, Lai D., Free PMC Article | 09/25/2021 |
| Dipeptidyl peptidase 3, a marker of the antagonist pathway of the renin-angiotensin-aldosterone system in patients with heart failure. | Dipeptidyl peptidase 3, a marker of the antagonist pathway of the renin-angiotensin-aldosterone system in patients with heart failure.
Boorsma EM, Ter Maaten JM, Damman K, van Veldhuisen DJ, Dickstein K, Anker SD, Filippatos G, Lang CC, Metra M, Santos K, Voors AA., Free PMC Article | 08/28/2021 |
| Plasma proenkephalin A 119-159 and dipeptidyl peptidase 3 on admission after cardiac arrest help predict long-term neurological outcome. | Plasma proenkephalin A 119-159 and dipeptidyl peptidase 3 on admission after cardiac arrest help predict long-term neurological outcome.
Thorgeirsdóttir B, Levin H, Spångfors M, Annborn M, Cronberg T, Nielsen N, Lybeck A, Friberg H, Frigyesi A. | 08/21/2021 |
| Circulatory dipeptidyl peptidase 3 (cDPP3) is a potential biomarker for early detection of secondary brain injury after aneurysmal subarachnoid hemorrhage. | Circulatory dipeptidyl peptidase 3 (cDPP3) is a potential biomarker for early detection of secondary brain injury after aneurysmal subarachnoid hemorrhage.
Neumaier F, Stoppe C, Veldeman M, Weiss M, Simon T, Hoellig A, Marx G, Clusmann H, Albanna W. | 07/10/2021 |
| Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients. | Circulating dipeptidyl peptidase-3 at admission is associated with circulatory failure, acute kidney injury and death in severely ill burn patients.
Dépret F, Amzallag J, Pollina A, Fayolle-Pivot L, Coutrot M, Chaussard M, Santos K, Hartmann O, Jully M, Fratani A, Oueslati H, Cupaciu A, Benyamina M, Guillemet L, Deniau B, Mebazaa A, Gayat E, Farny B, Textoris J, Legrand M, PRONOBURN group., Free PMC Article | 12/5/2020 |
| Enzyme-inhibitor complex is stabilized by intermolecular hydrogen bonding network, electrostatic and hydrophobic interactions which mostly involve constituent amino acid residues of the hDPP III substrate binding subsites S1, S1', S2, S2' and S3'. | Aprotinin interacts with substrate-binding site of human dipeptidyl peptidase III.
Agić D, Brkić H, Kazazić S, Tomić A, Abramić M. | 07/11/2020 |
| We conclude that DPP 3 may influence the cellular expression of Ang-(1-7) and potentially reflect a therapeutic target to augment the actions of the peptide | Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells.
Cruz-Diaz N, Wilson BA, Pirro NT, Brosnihan KB, Marshall AC, Chappell MC., Free PMC Article | 12/16/2017 |
| biological function of human dipeptidyl peptidase III | Human dipeptidyl peptidase III regulates G-protein coupled receptor-dependent Ca2+ concentration in human embryonic kidney 293T cells.
Prajapati SC, Singh R, Chauhan SS. | 06/24/2017 |
| several crystal structures of complexes of human dipeptidyl peptidase III with different peptides. | Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.
Kumar P, Reithofer V, Reisinger M, Wallner S, Pavkov-Keller T, Macheroux P, Gruber K., Free PMC Article | 02/18/2017 |
| Evidence for concurrent expression of hDPP III mRNA V-I and V-II in multiple human tumor derived cell lines. | Human dipeptidyl peptidase III mRNA variant I and II are expressed concurrently in multiple tumor derived cell lines and translated at comparable efficiency in vitro.
Prajapati SC, Chauhan SS. | 02/18/2017 |
| the DPP III conformational landscape and the influence of ligand binding on the protein structure and dynamics, was investigated. | Molecular simulations reveal that the long range fluctuations of human DPP III change upon ligand binding.
Tomić A, Berynskyy M, Wade RC, Tomić S. | 08/6/2016 |
| Kinetic studies revealed that the single mutant D496G lost selectivity due to the increase of the Km value. The D496G, but not S504G, showed significantly decreased binding of peptides with N-terminal arginine, and of tynorphin. | Aspartate 496 from the subsite S2 drives specificity of human dipeptidyl peptidase III.
Abramić M, Karačić Z, Šemanjski M, Vukelić B, Jajčanin-Jozić N. | 12/12/2015 |
| The study used three different conformations of human dipeptidyl-peptidase III (DPP III) to investigate the influence of the protein environment on ligand binding and the Zn(2+) coordination. | Hunting the human DPP III active conformation: combined thermodynamic and QM/MM calculations.
Tomić A, Tomić S. | 06/20/2015 |
| Deletion/mutagenesis of C/EBP-beta binding motif of DPP III promoter significantly increased its activity and abolished its responsiveness to IL-6 in glioblastoma cells. | Transcription factor C/EBP-β mediates downregulation of dipeptidyl-peptidase III expression by interleukin-6 in human glioblastoma cells.
Singh R, Sharma MC, Sarkar C, Singh M, Chauhan SS. | 05/17/2014 |
| The activity of the yeast and human dipeptidyl peptidase III were examined. | Hydrolysis of dipeptide derivatives reveals the diversity in the M49 family.
Jajčanin-Jozić N, Abramić M. | 03/22/2014 |
| Combined results of mutational analysis and mass spectrometry suggest that glutathionylation (formation of mixed disulfide) of Cys176 and Cys654 contributes to human DPP III inactivation by oxidized glutathione. | Molecular determinants of human dipeptidyl peptidase III sensitivity to thiol modifying reagents.
Karačić Z, Špoljarić J, Rožman M, Abramić M. | 07/13/2013 |
| Amplification and mRNA overexpression of the DPP3 gene is associated with squamous cell lung carcinomas. | Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.
Hast BE, Goldfarb D, Mulvaney KM, Hast MA, Siesser PF, Yan F, Hayes DN, Major MB., Free PMC Article | 06/29/2013 |