| The FAM13A Long Isoform Regulates Cilia Movement and Coordination in Airway Mucociliary Transport. | The FAM13A Long Isoform Regulates Cilia Movement and Coordination in Airway Mucociliary Transport.
Howes A, Rogerson C, Belyaev N, Karagyozova T, Rapiteanu R, Fradique R, Pellicciotta N, Mayhew D, Hurd C, Crotta S, Singh T, Dingwell K, Myatt A, Arad N, Hasan H, Bijlsma H, Panjwani A, Vijayan V, Young G, Bridges A, Petit-Frere S, Betts J, Larminie C, Smith JC, Hessel EM, Michalovich D, Walport L, Cicuta P, Powell AJ, Beinke S, Wack A., Free PMC Article | 10/9/2024 |
| Association of family sequence similarity gene 13A gene polymorphism and interstitial lung disease susceptibility: A systematic review and meta-analysis. | Association of family sequence similarity gene 13A gene polymorphism and interstitial lung disease susceptibility: A systematic review and meta-analysis.
Hu Y, Li Z, Ren Y, Dai H., Free PMC Article | 11/22/2023 |
| FAM13A regulates cellular senescence marker p21 and mitochondrial reactive oxygen species production in airway epithelial cells. | FAM13A regulates cellular senescence marker p21 and mitochondrial reactive oxygen species production in airway epithelial cells.
Chen Q, Vasse GF, Nwozor KO, Bekker NJ, van den Berge M, Brandsma CA, de Vries M, Heijink IH. | 09/26/2023 |
| FAM13A polymorphisms are associated with a specific susceptibility to clinical progression of oral cancer in alcohol drinkers. | FAM13A polymorphisms are associated with a specific susceptibility to clinical progression of oral cancer in alcohol drinkers.
Hsieh MJ, Lo YS, Tsai YJ, Ho HY, Lin CC, Chuang YC, Lin SH, Chen MK., Free PMC Article | 07/7/2023 |
| Single Nucleotide Polymorphisms of FAM13A Gene in Chronic Obstructive Pulmonary Disease-A Case Control Study in Vietnam. | Single Nucleotide Polymorphisms of FAM13A Gene in Chronic Obstructive Pulmonary Disease-A Case Control Study in Vietnam.
Pham KH, Tran NTC, Tran HD, Ngo TH, Tran V, Ly HHV, Pham NTN, Nguyen T, Nguyen BH, Nguyen KT., Free PMC Article | 06/29/2023 |
| The Influence of FAM13A and PPAR-gamma2 Gene Polymorphisms on the Metabolic State of Postmenopausal Women. | The Influence of FAM13A and PPAR-γ2 Gene Polymorphisms on the Metabolic State of Postmenopausal Women.
Grygiel-Górniak B, Ziółkowska-Suchanek I, Szymkowiak L, Rozwadowska N, Kaczmarek E., Free PMC Article | 05/5/2023 |
| Association of a FAM13A variant with interstitial lung disease in Japanese rheumatoid arthritis. | Association of a FAM13A variant with interstitial lung disease in Japanese rheumatoid arthritis.
Higuchi T, Oka S, Furukawa H, Shimada K, Tsunoda S, Ito S, Okamoto A, Katayama M, Saisho K, Shinohara S, Matsui T, Migita K, Nagaoka S, Tohma S., Free PMC Article | 02/4/2023 |
| miR30a5p induces the adipogenic differentiation of bone marrow mesenchymal stem cells by targeting FAM13A/Wnt/betacatenin signaling in aplastic anemia. | miR‑30a‑5p induces the adipogenic differentiation of bone marrow mesenchymal stem cells by targeting FAM13A/Wnt/β‑catenin signaling in aplastic anemia.
Wang E, Zhang Y, Ding R, Wang X, Zhang S, Li X., Free PMC Article | 03/12/2022 |
| Family with sequence similarity 13 member A mediates TGF-beta1-induced EMT in small airway epithelium of patients with chronic obstructive pulmonary disease. | Family with sequence similarity 13 member A mediates TGF-β1-induced EMT in small airway epithelium of patients with chronic obstructive pulmonary disease.
Zhu J, Wang F, Feng X, Li B, Ma L, Zhang J., Free PMC Article | 12/11/2021 |
| Connecting COPD GWAS Genes: FAM13A Controls TGFbeta2 Secretion by Modulating AP-3 Transport. | Connecting COPD GWAS Genes: FAM13A Controls TGFβ2 Secretion by Modulating AP-3 Transport.
Gong L, Bates S, Li J, Qiao D, Glass K, Wei W, Hsu VW, Zhou X, Silverman EK., Free PMC Article | 11/22/2021 |
| Role of Polymorphisms of FAM13A, PHLDB1, and CYP24A1 in Breast Cancer Risk. | Role of Polymorphisms of FAM13A, PHLDB1, and CYP24A1 in Breast Cancer Risk.
Wei Y, Wang X, Zhang Z, Xie M, Li Y, Cao H, Zhao X. | 11/22/2021 |
| FAM13A as potential therapeutic target in modulating TGF-beta-induced airway tissue remodeling in COPD. | FAM13A as potential therapeutic target in modulating TGF-β-induced airway tissue remodeling in COPD.
Tam A, Leclair P, Li LV, Yang CX, Li X, Witzigmann D, Kulkarni JA, Hackett TL, Dorscheid DR, Singhera GK, Hogg JC, Cullis PR, Sin DD, Lim CJ. | 09/25/2021 |
| Respiratory traits and coal workers' pneumoconiosis: Mendelian randomisation and association analysis. | Respiratory traits and coal workers' pneumoconiosis: Mendelian randomisation and association analysis.
Wang T, Sun W, Wu H, Cheng Y, Li Y, Meng F, Ni C. | 06/12/2021 |
| Loss of Family with Sequence Similarity 13, Member A Exacerbates Pulmonary Fibrosis Potentially by Promoting Epithelial to Mesenchymal Transition. | Loss of Family with Sequence Similarity 13, Member A Exacerbates Pulmonary Fibrosis Potentially by Promoting Epithelial to Mesenchymal Transition.
Rahardini EP, Ikeda K, Nugroho DB, Hirata KI, Emoto N., Free PMC Article | 11/21/2020 |
| GWAS-associated variants within the FAM13A locus alter adipose FAM13A expression, which in turn, regulates adipocyte differentiation and contribute to changes in body fat distribution. | FAM13A affects body fat distribution and adipocyte function.
Fathzadeh M, Li J, Rao A, Cook N, Chennamsetty I, Seldin M, Zhou X, Sangwung P, Gloudemans MJ, Keller M, Attie A, Yang J, Wabitsch M, Carcamo-Orive I, Tada Y, Lusis AJ, Shin MK, Molony CM, McLaughlin T, Reaven G, Montgomery SB, Reilly D, Quertermous T, Ingelsson E, Knowles JW., Free PMC Article | 07/18/2020 |
| Our results suggest that FAM13A is dispensable for adipose development and insulin sensitivity. Yet the expression of FAM13A needs to be tightly controlled in adipose precursor cells for their proper survival and downstream adipogenesis. These data provide novel insights into the link between FAM13A and obesity. | Obesity-associated family with sequence similarity 13, member A (FAM13A) is dispensable for adipose development and insulin sensitivity.
Tang J, Zhou H, Sahay K, Xu W, Yang J, Zhang W, Chen W., Free PMC Article | 04/25/2020 |
| Variant genotypes of rs9224 in the FAM13A 3'UTR may modify Lung squamous carcinoma (LUSQ) susceptibility by affecting the binding of miRNA-22-5p and predict a poor prognosis of patients with LUSQ. | Functional Variant in 3'UTR of FAM13A Is Potentially Associated with Susceptibility and Survival of Lung Squamous Carcinoma.
Yu Y, Mao L, Lu X, Yuan W, Chen Y, Jiang L, Ding L, Sang L, Xu Z, Tian T, Wu S, Zhuang X, Chu M. | 12/7/2019 |
| Data show that FAM13A is a modifier gene of Cystic Fibrosis lung phenotype regulating RhoA activity, actin cytoskeleton dynamics and epithelial-mesenchymal transition. | FAM13A is a modifier gene of cystic fibrosis lung phenotype regulating rhoa activity, actin cytoskeleton dynamics and epithelial-mesenchymal transition.
Corvol H, Rousselet N, Thompson KE, Berdah L, Cottin G, Foussigniere T, Longchampt E, Fiette L, Sage E, Prunier C, Drumm M, Hodges CA, Boëlle PY, Guillot L. | 11/16/2019 |
| rs2013701 as a functional variant likely to contribute to the development of COPD | Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays.
Castaldi PJ, Guo F, Qiao D, Du F, Naing ZZC, Li Y, Pham B, Mikkelsen TS, Cho MH, Silverman EK, Zhou X., Free PMC Article | 10/19/2019 |
| High expression of FAM13A may be associated with an increased risk of liver cirrhosis. Risk of liver cirrhosis was significantly associated with G/A-G/G genotype of rs3017895. | High expression of FAM13A was associated with increasing the liver cirrhosis risk.
Zhang Y, Wang S, Wang C, Xiao J, Zhang S, Zhou H., Free PMC Article | 05/11/2019 |
| Gene expression and adipocyte functional studies support the notion that FAM13A and POM121C control adipocyte lipolysis and adipogenesis, respectively, and might thereby be involved in genetic control of systemic insulin sensitivity | FAM13A and POM121C are candidate genes for fasting insulin: functional follow-up analysis of a genome-wide association study.
Lundbäck V, Kulyte A, Strawbridge RJ, Ryden M, Arner P, Marcus C, Dahlman I., Free PMC Article | 02/2/2019 |
| rs17014601 in FAM13A was significantly associated with COPD in the additive (odds ratio [OR]=1.36, 95% confidence interval [CI]: 1.11-1.67, P=0.003), heterozygote (OR=1.76, 95% CI: 1.33-2.32, P=0.0001), and dominant (OR=1.67, 95% CI: 1.28-2.18, P=0.0001) models. Stratified analyses indicated that the risk was higher in never smokers. | Genetic variants in FAM13A and IREB2 are associated with the susceptibility to COPD in a Chinese rural population: a case-control study.
Zhang Y, Qiu J, Zhang P, Zhang J, Jiang M, Ma Z., Free PMC Article | 01/19/2019 |
| The rs2609255 in FAM13A gene may modify silicosis susceptibility in the Chinese population. | The rs2609255 polymorphism in the FAM13A gene is reproducibly associated with silicosis susceptibility in a Chinese population.
Wang W, Yu Y, Wu S, Sang L, Wang X, Qiu A, Yu X, Li J, Zhang L, Yi M, Zheng H, Gao Y, Xiao J, Lu Y, Jiang L, Lian Y, Zhuang X, Tian T, Chu M. | 06/2/2018 |
| noncoding FAM13A polymorphisms were correlated with gene expression levels, and thus were probably in linkage disequilibrium with genetic loci that regulated the expression of FAM13A | FAM13A, A Fatty Acid Oxidation Switch in Mitochondria. Friend or Foe in Chronic Obstructive Pulmonary Disease Pathogenesis?
Hawkins GA, Mora AL., Free PMC Article | 02/24/2018 |
| FAM13A gene polymorphism showed a significant association with the susceptibility to idiopathic pulmonary fibrosis, with severity of lung function impairment and with poor prognosis. | FAM13A polymorphism as a prognostic factor in patients with idiopathic pulmonary fibrosis.
Hirano C, Ohshimo S, Horimasu Y, Iwamoto H, Fujitaka K, Hamada H, Hattori N, Shime N, Bonella F, Guzman J, Costabel U, Kohno N. | 01/13/2018 |