| OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1[S824]. | OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1(S824).
Lam SY, van der Lugt R, Cerutti A, Yalçin Z, Thouin AM, Simonetta M, Jacobs JJL., Free PMC Article | 10/18/2024 |
| TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation. | TRIM28 promotes tumor growth and metastasis in breast cancer by targeting the BRD7 protein for ubiquitination and degradation.
Xue C, Meng H, Niu W, Li M, Wei J, Chen S, Zheng L, Duan Y, Deng H, Tang F, Fan S, Tan M, Xiong W, Zhou M. | 10/15/2024 |
| TIF1beta activates leukemic transcriptional program in HSCs and promotes BCR::ABL1-induced myeloid leukemia. | TIF1β activates leukemic transcriptional program in HSCs and promotes BCR::ABL1-induced myeloid leukemia.
Morii M, Kubota S, Iimori M, Yokomizo-Nakano T, Hamashima A, Bai J, Nishimura A, Tasaki M, Ando Y, Araki K, Sashida G. | 10/7/2024 |
| Satellite cell-derived TRIM28 is pivotal for mechanical load- and injury-induced myogenesis. | Satellite cell-derived TRIM28 is pivotal for mechanical load- and injury-induced myogenesis.
Lin KH, Hibbert JE, Flynn CG, Lemens JL, Torbey MM, Steinert ND, Flejsierowicz PM, Melka KM, Lindley GT, Lares M, Setaluri V, Wagers AJ, Hornberger TA., Free PMC Article | 09/18/2024 |
| KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m[6]A reader YTHDC1 protein degradation. | KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m(6)A reader YTHDC1 protein degradation.
Yang Y, Zhang Y, Chen G, Sun B, Luo F, Gao Y, Feng H, Li Y., Free PMC Article | 07/17/2024 |
| [Expression and prognostic significance of KAP1 gene in malignant pleural mesothelioma]. | [Expression and prognostic significance of KAP1 gene in malignant pleural mesothelioma].
Mei W, Wang XM, Liu RA, Xiong W, Zhang YP. | 05/7/2024 |
| Up-regulation of Trim28 in pregnancy-induced hypertension is involved in the injury of human umbilical vein endothelial cells through the p38 signaling pathway. | Up-regulation of Trim28 in pregnancy-induced hypertension is involved in the injury of human umbilical vein endothelial cells through the p38 signaling pathway.
Chen M, Shi P, Wang P, Zhang T, Zhao J, Zhao L. | 05/6/2024 |
| Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation. | Functional Analysis of KAP1/TRIM28 Requirements for HIV-1 Transcription Activation.
Randolph K, Hyder U, Challa A, Perez E, D'Orso I., Free PMC Article | 02/20/2024 |
| TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/beta-catenin signaling pathways. | TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/β-catenin signaling pathways.
Ning T, Zhao M, Zhang N, Wang Z, Zhang S, Liu M, Zhu S., Free PMC Article | 02/2/2024 |
| TRIM28 inactivation in epithelial nephroblastoma is frequent and often associated with predisposing TRIM28 germline variants. | TRIM28 inactivation in epithelial nephroblastoma is frequent and often associated with predisposing TRIM28 germline variants.
Wegert J, Fischer AK, Palhazi B, Treger TD, Hilgers C, Ziegler B, Jung H, Jüttner E, Waha A, Fuchs J, Warmann SW, Frühwald MC, Hubertus J, Pritchard-Jones K, Graf N, Behjati S, Furtwängler R, Gessler M, Vokuhl C. | 12/16/2023 |
| ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication. | ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication.
Xu H, Akinyemi IA, Haley J, McIntosh MT, Bhaduri-McIntosh S., Free PMC Article | 11/18/2023 |
| E3 ligase TRIM28 promotes anti-PD-1 resistance in non-small cell lung cancer by enhancing the recruitment of myeloid-derived suppressor cells. | E3 ligase TRIM28 promotes anti-PD-1 resistance in non-small cell lung cancer by enhancing the recruitment of myeloid-derived suppressor cells.
Liang M, Sun Z, Chen X, Wang L, Wang H, Qin L, Zhao W, Geng B., Free PMC Article | 11/1/2023 |
| A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells. | A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells.
Ginn L, Maltas J, Baker MJ, Chaturvedi A, Wilson L, Guilbert R, Amaral FMR, Priest L, Mole H, Blackhall F, Diamantopoulou Z, Somervaille TCP, Hurlstone A, Malliri A., Free PMC Article | 09/30/2023 |
| Children with Chronic Immune Thrombocytopenia Exhibit High Expression of Human Endogenous Retroviruses TRIM28 and SETDB1. | Children with Chronic Immune Thrombocytopenia Exhibit High Expression of Human Endogenous Retroviruses TRIM28 and SETDB1.
Tovo PA, Galliano I, Parodi E, Calvi C, Gambarino S, Licciardi F, Dini M, Montanari P, Branca M, Ramenghi U, Bergallo M., Free PMC Article | 08/30/2023 |
| N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA damage and apoptosis through TRIM28 in intervertebral disc degeneration. | N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA damage and apoptosis through TRIM28 in intervertebral disc degeneration.
Chen Z, Song J, Xie L, Xu G, Zheng C, Xia X, Lu F, Ma X, Zou F, Jiang J, Wang H., Free PMC Article | 08/10/2023 |
| WDR4/TRIM28 is a novel molecular target linked to lenvatinib resistance that helps retain the stem characteristics in hepatocellular carcinomas. | WDR4/TRIM28 is a novel molecular target linked to lenvatinib resistance that helps retain the stem characteristics in hepatocellular carcinomas.
Han WY, Wang J, Zhao J, Zheng YM, Chai XQ, Gao C, Cai JB, Ke AW, Fan J, Gao PT, Sun HX. | 07/23/2023 |
| Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells. | Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.
Chang YJ, Lin S, Kang ZF, Shen BJ, Tsai WH, Chen WC, Lu HP, Su YL, Chou SJ, Lin SY, Lin SW, Huang YJ, Wang HH, Chang CJ., Free PMC Article | 06/30/2023 |
| TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy. | TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy.
Song T, Lv S, Ma X, Zhao X, Fan L, Zou Q, Li N, Yan Y, Zhang W, Sun L., Free PMC Article | 06/1/2023 |
| A novel role of TRIM28 B box domain in L1 retrotransposition and ORF2p-mediated cDNA synthesis. | A novel role of TRIM28 B box domain in L1 retrotransposition and ORF2p-mediated cDNA synthesis.
Du Q, Stow EC, LaCoste D, Freeman B, Baddoo M, Shareef AM, Miller KM, Belancio VP., Free PMC Article | 06/1/2023 |
| Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis. | Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis.
Tovo PA, Marozio L, Abbona G, Calvi C, Frezet F, Gambarino S, Dini M, Benedetto C, Galliano I, Bergallo M., Free PMC Article | 04/6/2023 |
| SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors. | SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors.
Huang Z, Li X, Tang B, Li H, Zhang J, Sun R, Ma J, Pan Y, Yan B, Zhou Y, Ding D, Yan Y, Jimenez R, Orme JJ, Jin X, Yang J, Huang H, Jia Z. | 03/17/2023 |
| CRISPR/Cas9-Mediated Disruption of ZNF543 Gene: An Approach Toward Discovering Its Relation to TRIM28 Gene in Parkinson's Disease. | CRISPR/Cas9-Mediated Disruption of ZNF543 Gene: An Approach Toward Discovering Its Relation to TRIM28 Gene in Parkinson's Disease.
Hashemabadi M, Sasan H, Amandadi M, Esmaeilzadeh-Salestani K, Esmaeili-Mahani S, Ravan H. | 01/21/2023 |
| The bromodomain protein TRIM28 controls the balance between growth and invasiveness in melanoma. | The bromodomain protein TRIM28 controls the balance between growth and invasiveness in melanoma.
Nyberg WA, Velasquez-Pulgarin DA, He T, Sjöstrand M, Pellé L, Covacu R, Espinosa A., Free PMC Article | 01/14/2023 |
| LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination. | LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination.
Tsang SV, Rainusso N, Liu M, Nomura M, Patel TD, Nakahata K, Kim HR, Huang S, Rajapakshe K, Coarfa C, Man TK, Rao PH, Yustein JT. | 01/7/2023 |
| Structure and functional mapping of the KRAB-KAP1 repressor complex. | Structure and functional mapping of the KRAB-KAP1 repressor complex.
Stoll GA, Pandiloski N, Douse CH, Modis Y., Free PMC Article | 12/24/2022 |