Long non-coding RNA NBR2 suppresses the progression of colorectal cancer by downregulating miR-19a to regulate M2 macrophage polarization. | Long non-coding RNA NBR2 suppresses the progression of colorectal cancer by downregulating miR-19a to regulate M2 macrophage polarization. Yang X, Luo Y, Li M, Jin Z, Chen G, Gan C. | 01/4/2024 |
LncRNA NBR2 Regulates Cancer Cell Stemness and Predicts Survival in Non-small Cell Cancer Patients by Downregulating TGF-beta1. | LncRNA NBR2 Regulates Cancer Cell Stemness and Predicts Survival in Non-small Cell Cancer Patients by Downregulating TGF-β1. Huang J, Yu Q, Zhang J, Lu W, Liu Q, Chu Y, Zhou Y, Tu R, Zhou H, Wang Q. | 06/1/2023 |
NBR2/miR-561-5p/DLC1 axis inhibited the development of multiple myeloma by activating the AMPK/mTOR pathway to repress glycolysis. | NBR2/miR-561-5p/DLC1 axis inhibited the development of multiple myeloma by activating the AMPK/mTOR pathway to repress glycolysis. Wang CS, Zhang XB, Zhu XT, Chen RS. | 10/22/2022 |
LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis. | LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis. Zhu C, He X, Chen K, Huang Z, Yao A, Tian X, You Y, Zeng M., Free PMC Article | 01/29/2022 |
Long non-coding RNA NBR2 suppresses the progress of colorectal cancer in vitro and in vivo by regulating the polarization of TAM. | Long non-coding RNA NBR2 suppresses the progress of colorectal cancer in vitro and in vivo by regulating the polarization of TAM. Lai F, Zhang H, Xu B, Xie Y, Yu H., Free PMC Article | 12/25/2021 |
NBR2 promotes the proliferation of glioma cells via inhibiting p15 expression. | NBR2 promotes the proliferation of glioma cells via inhibiting p15 expression. Zhang J, Jiang H, Feng X, Wang L, Yang X. | 12/25/2021 |
LncRNA NBR2 inhibits tumorigenesis by regulating autophagy in hepatocellular carcinoma. | LncRNA NBR2 inhibits tumorigenesis by regulating autophagy in hepatocellular carcinoma. Sheng JQ, Wang MR, Fang D, Liu L, Huang WJ, Tian DA, He XX, Li PY. | 02/27/2021 |
LncRNA NBR2 inhibits EMT progression by regulating Notch1 pathway in NSCLC. | LncRNA NBR2 inhibits EMT progression by regulating Notch1 pathway in NSCLC. Gao YP, Li Y, Li HJ, Zhao B. | 10/10/2020 |
This study revealed a novel mechanism by which long noncoding RNA NBR2 mediates curcumin suppression of colorectal cancer proliferation by activating adenosine monophosphate-activated protein kinase and inactivating the mTOR signaling pathway. | Curcumin Regulates the Progression of Colorectal Cancer via LncRNA NBR2/AMPK Pathway. Yu H, Xie Y, Zhou Z, Wu Z, Dai X, Xu B., Free PMC Article | 05/9/2020 |
data suggested that miR-19a negatively controlled the autophagy of hepatocytes attenuated in D-GalN/LPS-stimulated hepatocytes via regulating NBR2 and AMPK/PPARalpha signaling. | MiR-19a Affects Hepatocyte Autophagy via Regulating lncRNA NBR2 and AMPK/PPARα in D-GalN/Lipopolysaccharide-Stimulated Hepatocytes. Liu YM, Ma JH, Zeng QL, Lv J, Xie XH, Pan YJ, Yu ZJ. | 06/2/2018 |
NBR2-GLUT1 axis may serve as an adaptive response in cancer cells to survive in response to phenformin treatment. | lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1. Liu X, Gan B, Liu X, Gan B., Free PMC Articles: PMC5224451, PMC5224451 | 07/1/2017 |
High NBR2 expression is associated with breast cancer. | Induction of the long noncoding RNA NBR2 from the bidirectional BRCA1 promoter under hypoxic conditions. Wiedmeier JE, Ohlrich A, Chu A, Rountree MR, Turker MS. | 05/27/2017 |
Data indicate that long non-coding RNAs (lncRNAs) NBR2 (neighbour of BRCA1 gene 2) modulates cancer cell sensitivity to phenformin through NBR2 regulation of GLUT1 expression at transcriptional level. | lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1. Liu X, Gan B, Liu X, Gan B., Free PMC Articles: PMC5224451, PMC5224451 | 11/25/2016 |
Data indicate that long non-coding RNAs (lncRNAs) NBR2 (neighbour of BRCA1 gene 2) interacts with AMP-activated kinase (AMPK) and promotes AMPK kinase activity during energy stress. | LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Liu X, Xiao ZD, Han L, Zhang J, Lee SW, Wang W, Lee H, Zhuang L, Chen J, Lin HK, Wang J, Liang H, Gan B., Free PMC Article | 08/27/2016 |