U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    NBR2 neighbor of BRCA1 lncRNA 2 [ Homo sapiens (human) ]

    Gene ID: 10230, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Long non-coding RNA NBR2 suppresses the progression of colorectal cancer by downregulating miR-19a to regulate M2 macrophage polarization.

    Long non-coding RNA NBR2 suppresses the progression of colorectal cancer by downregulating miR-19a to regulate M2 macrophage polarization.
    Yang X, Luo Y, Li M, Jin Z, Chen G, Gan C.

    01/4/2024
    LncRNA NBR2 Regulates Cancer Cell Stemness and Predicts Survival in Non-small Cell Cancer Patients by Downregulating TGF-beta1.

    LncRNA NBR2 Regulates Cancer Cell Stemness and Predicts Survival in Non-small Cell Cancer Patients by Downregulating TGF-β1.
    Huang J, Yu Q, Zhang J, Lu W, Liu Q, Chu Y, Zhou Y, Tu R, Zhou H, Wang Q.

    06/1/2023
    NBR2/miR-561-5p/DLC1 axis inhibited the development of multiple myeloma by activating the AMPK/mTOR pathway to repress glycolysis.

    NBR2/miR-561-5p/DLC1 axis inhibited the development of multiple myeloma by activating the AMPK/mTOR pathway to repress glycolysis.
    Wang CS, Zhang XB, Zhu XT, Chen RS.

    10/22/2022
    LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.

    LncRNA NBR2 aggravates hepatoblastoma cell malignancy and promotes cell proliferation under glucose starvation through the miR-22/TCF7 axis.
    Zhu C, He X, Chen K, Huang Z, Yao A, Tian X, You Y, Zeng M., Free PMC Article

    01/29/2022
    Long non-coding RNA NBR2 suppresses the progress of colorectal cancer in vitro and in vivo by regulating the polarization of TAM.

    Long non-coding RNA NBR2 suppresses the progress of colorectal cancer in vitro and in vivo by regulating the polarization of TAM.
    Lai F, Zhang H, Xu B, Xie Y, Yu H., Free PMC Article

    12/25/2021
    NBR2 promotes the proliferation of glioma cells via inhibiting p15 expression.

    NBR2 promotes the proliferation of glioma cells via inhibiting p15 expression.
    Zhang J, Jiang H, Feng X, Wang L, Yang X.

    12/25/2021
    LncRNA NBR2 inhibits tumorigenesis by regulating autophagy in hepatocellular carcinoma.

    LncRNA NBR2 inhibits tumorigenesis by regulating autophagy in hepatocellular carcinoma.
    Sheng JQ, Wang MR, Fang D, Liu L, Huang WJ, Tian DA, He XX, Li PY.

    02/27/2021
    LncRNA NBR2 inhibits EMT progression by regulating Notch1 pathway in NSCLC.

    LncRNA NBR2 inhibits EMT progression by regulating Notch1 pathway in NSCLC.
    Gao YP, Li Y, Li HJ, Zhao B.

    10/10/2020
    This study revealed a novel mechanism by which long noncoding RNA NBR2 mediates curcumin suppression of colorectal cancer proliferation by activating adenosine monophosphate-activated protein kinase and inactivating the mTOR signaling pathway.

    Curcumin Regulates the Progression of Colorectal Cancer via LncRNA NBR2/AMPK Pathway.
    Yu H, Xie Y, Zhou Z, Wu Z, Dai X, Xu B., Free PMC Article

    05/9/2020
    data suggested that miR-19a negatively controlled the autophagy of hepatocytes attenuated in D-GalN/LPS-stimulated hepatocytes via regulating NBR2 and AMPK/PPARalpha signaling.

    MiR-19a Affects Hepatocyte Autophagy via Regulating lncRNA NBR2 and AMPK/PPARα in D-GalN/Lipopolysaccharide-Stimulated Hepatocytes.
    Liu YM, Ma JH, Zeng QL, Lv J, Xie XH, Pan YJ, Yu ZJ.

    06/2/2018
    NBR2-GLUT1 axis may serve as an adaptive response in cancer cells to survive in response to phenformin treatment.

    lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1.
    Liu X, Gan B, Liu X, Gan B., Free PMC Articles: PMC5224451, PMC5224451

    07/1/2017
    High NBR2 expression is associated with breast cancer.

    Induction of the long noncoding RNA NBR2 from the bidirectional BRCA1 promoter under hypoxic conditions.
    Wiedmeier JE, Ohlrich A, Chu A, Rountree MR, Turker MS.

    05/27/2017
    Data indicate that long non-coding RNAs (lncRNAs) NBR2 (neighbour of BRCA1 gene 2) modulates cancer cell sensitivity to phenformin through NBR2 regulation of GLUT1 expression at transcriptional level.

    lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1.
    Liu X, Gan B, Liu X, Gan B., Free PMC Articles: PMC5224451, PMC5224451

    11/25/2016
    Data indicate that long non-coding RNAs (lncRNAs) NBR2 (neighbour of BRCA1 gene 2) interacts with AMP-activated kinase (AMPK) and promotes AMPK kinase activity during energy stress.

    LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress.
    Liu X, Xiao ZD, Han L, Zhang J, Lee SW, Wang W, Lee H, Zhuang L, Chen J, Lin HK, Wang J, Liang H, Gan B., Free PMC Article

    08/27/2016
    firstprevious page of 1 nextlast