| SIGMAR1 targets AMPK/ULK1 pathway to inhibit SH-SY5Y cell apoptosis by regulating endoplasmic reticulum stress and autophagy. | SIGMAR1 targets AMPK/ULK1 pathway to inhibit SH-SY5Y cell apoptosis by regulating endoplasmic reticulum stress and autophagy.
Kong M, Chen Z, Lin Z, Yin P, Zhao Q. | 09/13/2024 |
| Unraveling the CLCC1 interactome: Impact of the Asp25Glu variant and its interaction with SigmaR1 at the Mitochondrial-Associated ER Membrane (MAM). | Unraveling the CLCC1 interactome: Impact of the Asp25Glu variant and its interaction with SigmaR1 at the Mitochondrial-Associated ER Membrane (MAM).
D'Atri I, Martin ER, Yang L, Sears E, Baple E, Crosby AH, Chilton JK, Oguro-Ando A. | 05/24/2024 |
| The Sigma-1 Receptor Is a Novel Target for Improving Cold Preservation in Rodent Kidney Transplants. | The Sigma-1 Receptor Is a Novel Target for Improving Cold Preservation in Rodent Kidney Transplants.
Hosszu A, Toth AR, Lakat T, Stepanova G, Antal Z, Wagner LJ, Szabo AJ, Fekete A., Free PMC Article | 08/19/2023 |
| Sig1R activates extracellular matrix-induced bladder cancer cell proliferation and angiogenesis by combing beta-integrin. | Sig1R activates extracellular matrix-induced bladder cancer cell proliferation and angiogenesis by combing β-integrin.
Zhao F, Yang T, Zhou L, Li R, Liu J, Zhao J, Jia R., Free PMC Article | 06/15/2023 |
| SIGMAR1 Confers Innate Resilience against Neurodegeneration. | SIGMAR1 Confers Innate Resilience against Neurodegeneration.
Couly S, Yasui Y, Su TP., Free PMC Article | 05/19/2023 |
| Investigation of the Entry Pathway and Molecular Nature of sigma1 Receptor Ligands. | Investigation of the Entry Pathway and Molecular Nature of σ1 Receptor Ligands.
Pascarella G, Antonelli L, Narzi D, Battista T, Fiorillo A, Colotti G, Guidoni L, Morea V, Ilari A., Free PMC Article | 04/14/2023 |
| Sigma-1 Receptor Signaling: In Search of New Therapeutic Alternatives for Cardiovascular and Renal Diseases. | Sigma-1 Receptor Signaling: In Search of New Therapeutic Alternatives for Cardiovascular and Renal Diseases.
Munguia-Galaviz FJ, Miranda-Diaz AG, Cardenas-Sosa MA, Echavarria R., Free PMC Article | 03/1/2023 |
| Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection. | Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection.
Lachance V, Bélanger SM, Hay C, Le Corvec V, Banouvong V, Lapalme M, Tarmoun K, Beaucaire G, Lussier MP, Kourrich S., Free PMC Article | 03/1/2023 |
| An investigation of Sigma-1 receptor expression and ligand-induced endoplasmic reticulum stress in breast cancer. | An investigation of Sigma-1 receptor expression and ligand-induced endoplasmic reticulum stress in breast cancer.
Borde P, Cosgrove N, Charmsaz S, Safrany ST, Young L. | 02/22/2023 |
| TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy. | TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy.
Marcotti A, Fernández-Trillo J, González A, Vizcaíno-Escoto M, Ros-Arlanzón P, Romero L, Vela JM, Gomis A, Viana F, de la Peña E., Free PMC Article | 02/16/2023 |
| Sigma-1 Receptor in Retina: Neuroprotective Effects and Potential Mechanisms. | Sigma-1 Receptor in Retina: Neuroprotective Effects and Potential Mechanisms.
Xu Z, Lei Y, Qin H, Zhang S, Li P, Yao K., Free PMC Article | 08/13/2022 |
| The Sigma-1 receptor is an ER-localized type II membrane protein. | The Sigma-1 receptor is an ER-localized type II membrane protein.
Sharma N, Patel C, Shenkman M, Kessel A, Ben-Tal N, Lederkremer GZ., Free PMC Article | 12/18/2021 |
| Sigma1 Receptor Inhibits TRPC1-Mediated Ca(2+) Entry That Promotes Dopaminergic Cell Death. | Sigma1 Receptor Inhibits TRPC1-Mediated Ca(2+) Entry That Promotes Dopaminergic Cell Death.
Sun Y, Sukumaran P, Singh BB. | 12/11/2021 |
| Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain. | Sigma-1 receptor: A drug target for the modulation of neuroimmune and neuroglial interactions during chronic pain.
Ruiz-Cantero MC, González-Cano R, Tejada MÁ, Santos-Caballero M, Perazzoli G, Nieto FR, Cobos EJ. | 11/22/2021 |
| Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated H2O2 Permeability: New Tools for Counteracting Oxidative Stress. | Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated H(2)O(2) Permeability: New Tools for Counteracting Oxidative Stress.
Pellavio G, Rossino G, Gastaldi G, Rossi D, Linciano P, Collina S, Laforenza U., Free PMC Article | 10/23/2021 |
| The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains. | The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains.
Zhemkov V, Ditlev JA, Lee WR, Wilson M, Liou J, Rosen MK, Bezprozvanny I., Free PMC Article | 10/23/2021 |
| Involvement of Sigma Receptor-1 in Lymphatic Endothelial Barrier Integrity and Bioenergetic Regulation. | Involvement of Sigma Receptor-1 in Lymphatic Endothelial Barrier Integrity and Bioenergetic Regulation.
Motawe ZY, Abdelmaboud SS, Breslin JW., Free PMC Article | 09/25/2021 |
| The Sigma-1 Receptor at the Crossroad of Proteostasis, Neurodegeneration, and Autophagy. | The Sigma-1 Receptor at the Crossroad of Proteostasis, Neurodegeneration, and Autophagy.
Christ MG, Clement AM, Behl C. | 09/18/2021 |
| Sigma-1 receptor activation-induced glycolytic ATP production and endothelial barrier enhancement. | Sigma-1 receptor activation-induced glycolytic ATP production and endothelial barrier enhancement.
Motawe ZY, Farsaei F, Abdelmaboud SS, Cuevas J, Breslin JW., Free PMC Article | 08/21/2021 |
| Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis. | Sigma-1 receptor is involved in diminished ovarian reserve possibly by influencing endoplasmic reticulum stress-mediated granulosa cells apoptosis.
Jiang L, Cui J, Zhang C, Xie J, Zhang S, Fu D, Duo W., Free PMC Article | 08/7/2021 |
| Normalization of Calcium Balance in Striatal Neurons in Huntington's Disease: Sigma 1 Receptor as a Potential Target for Therapy. | Normalization of Calcium Balance in Striatal Neurons in Huntington's Disease: Sigma 1 Receptor as a Potential Target for Therapy.
Kraskovskaya NA, Bezprozvanny IB. | 07/17/2021 |
| Sigma-1 Receptor (S1R) Interaction with Cholesterol: Mechanisms of S1R Activation and Its Role in Neurodegenerative Diseases. | Sigma-1 Receptor (S1R) Interaction with Cholesterol: Mechanisms of S1R Activation and Its Role in Neurodegenerative Diseases.
Zhemkov V, Geva M, Hayden MR, Bezprozvanny I., Free PMC Article | 05/15/2021 |
| Methamphetamine Blocks Adenosine A2A Receptor Activation via Sigma 1 and Cannabinoid CB1 Receptors. | Methamphetamine Blocks Adenosine A(2A) Receptor Activation via Sigma 1 and Cannabinoid CB(1) Receptors.
Casanovas M, Reyes-Resina I, Lillo A, Lillo J, López-Arnau R, Camarasa J, Escubedo E, Navarro G, Franco R., Free PMC Article | 05/1/2021 |
| Urinary bladder sigma-1 receptors: A new target for cystitis treatment. | Urinary bladder sigma-1 receptors: A new target for cystitis treatment.
González-Cano R, Artacho-Cordón A, Romero L, Tejada MA, Nieto FR, Merlos M, Cañizares FJ, Cendán CM, Fernández-Segura E, Baeyens JM. | 04/3/2021 |
| Sigma-1 receptor is a key genetic modulator in amyotrophic lateral sclerosis. | Sigma-1 receptor is a key genetic modulator in amyotrophic lateral sclerosis.
Couly S, Khalil B, Viguier V, Roussel J, Maurice T, Liévens JC. | 04/3/2021 |