Cellular and electrophysiological characterization of triadin knockout syndrome using induced pluripotent stem cell-derived cardiomyocytes. | Cellular and electrophysiological characterization of triadin knockout syndrome using induced pluripotent stem cell-derived cardiomyocytes. Clemens DJ, Ye D, Wang L, Kim CSJ, Zhou W, Dotzler SM, Tester DJ, Marty I, Knollmann BC, Ackerman MJ., Free PMC Article | 05/17/2023 |
Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart. | Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart. Zhao Y, Riching AS, Knight WE, Chi C, Broadwell LJ, Du Y, Abdel-Hafiz M, Ambardekar AV, Irwin DC, Proenza C, Xu H, Leinwand LA, Walker LA, Woulfe KC, Bristow MR, Buttrick PM, Song K., Free PMC Article | 09/3/2022 |
Association of decreased triadin expression level with apoptosis of dopaminergic cells in Parkinson's disease mouse model. | Association of decreased triadin expression level with apoptosis of dopaminergic cells in Parkinson's disease mouse model. Seo MH, Lim S, Yeo S., Free PMC Article | 03/5/2022 |
Novel cases of pediatric sudden cardiac death secondary to TRDN mutations presenting as long QT syndrome at rest and catecholaminergic polymorphic ventricular tachycardia during exercise: The TRDN arrhythmia syndrome. | Novel cases of pediatric sudden cardiac death secondary to TRDN mutations presenting as long QT syndrome at rest and catecholaminergic polymorphic ventricular tachycardia during exercise: The TRDN arrhythmia syndrome. Rabbani B, Khorgami M, Dalili M, Zamani N, Mahdieh N, Gollob MH. | 02/19/2022 |
A novel homozygous mutation in the TRDN gene causes a severe form of pediatric malignant ventricular arrhythmia. | A novel homozygous mutation in the TRDN gene causes a severe form of pediatric malignant ventricular arrhythmia. Rossi D, Gigli L, Gamberucci A, Bordoni R, Pietrelli A, Lorenzini S, Pierantozzi E, Peretto G, De Bellis G, Della Bella P, Ferrari M, Sorrentino V, Benedetti S, Sala S, Di Resta C. | 05/1/2021 |
The lncRNA TRDN-AS regulates the balance between cardiac and skeletal isoforms of triadin. | A heart-enriched antisense long non-coding RNA regulates the balance between cardiac and skeletal muscle triadin. Zhang L, Salgado-Somoza A, Vausort M, Leszek P, Devaux Y, Cardiolinc™ network. Electronic address: https://www.cardiolinc.org. | 04/21/2018 |
CLIMP-63 (also known as CKAP4), is the partner of triadin, is responsible for this association of triads and microtubules. | Triadin and CLIMP-63 form a link between triads and microtubules in muscle cells. Osseni A, Sébastien M, Sarrault O, Baudet M, Couté Y, Fauré J, Fourest-Lieuvin A, Marty I. | 08/5/2017 |
A compound heterozygous mutation in the triadin gene resulted in a particularly arrhythmogenic phenotype with with cardiac arrest in two siblings. | Compound Heterozygous Triadin Mutation Causing Cardiac Arrest in Two Siblings. Walsh MA, Stuart AG, Schlecht HB, James AF, Hancox JC, Newbury-Ecob RA. | 06/3/2017 |
We describe a new family with cathecholaminergic polymorphic ventricular tachycardia (CPVT) linked to the Triadin gene. | New Family With Catecholaminergic Polymorphic Ventricular Tachycardia Linked to the Triadin Gene. Rooryck C, Kyndt F, Bozon D, Roux-Buisson N, Sacher F, Probst V, Thambo JB. | 07/30/2016 |
Common variants in TRDN and CALM1 are associated with increased risk of sudden cardiac death in patients with chronic heart failure. | Common Variants in TRDN and CALM1 Are Associated with Risk of Sudden Cardiac Death in Chronic Heart Failure Patients in Chinese Han Population. Liu Z, Liu X, Yu H, Pei J, Zhang Y, Gong J, Pu J., Free PMC Article | 05/7/2016 |
TRDN is a novel underlying genetic basis for recessively inherited Long-QT syndrome. | Homozygous/Compound Heterozygous Triadin Mutations Associated With Autosomal-Recessive Long-QT Syndrome and Pediatric Sudden Cardiac Arrest: Elucidation of the Triadin Knockout Syndrome. Altmann HM, Tester DJ, Will ML, Middha S, Evans JM, Eckloff BW, Ackerman MJ. | 09/26/2015 |
Data show that triadin (TRDN) is a new gene responsible for an autosomal recessive form of ctecholaminergic polymorphic ventricular tachycardia (CPVT). | Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human. Roux-Buisson N, Cacheux M, Fourest-Lieuvin A, Fauconnier J, Brocard J, Denjoy I, Durand P, Guicheney P, Kyndt F, Leenhardt A, Le Marec H, Lucet V, Mabo P, Probst V, Monnier N, Ray PF, Santoni E, Trémeaux P, Lacampagne A, Fauré J, Lunardi J, Marty I., Free PMC Article | 10/13/2012 |
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
The researchers found evidence that TRDN may be a susceptibility or marker gene for IgA nephropathy | Parallel genotyping of 10,204 single nucleotide polymorphisms to screen for susceptible genes for IgA nephropathy. Woo KT, Lau YK, Wong KS, Zhao Y, Chan CM, Woo KT, Lau YK, Wong KS, Zhao Y, Chan CM. | 02/8/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesFamily-based association study for bipolar affective disorder. Secolin R, Banzato CE, Oliveira MC, Bittar MF, Santos ML, Dalgalarrondo P, Lopes-Cendes I. Parallel genotyping of 10,204 single nucleotide polymorphisms to screen for susceptible genes for IgA nephropathy. Woo KT, Lau YK, Wong KS, Zhao Y, Chan CM, Woo KT, Lau YK, Wong KS, Zhao Y, Chan CM. | 12/2/2009 |
Histidine-rich Ca-binding protein may play a key role in the regulation of SR Ca cycling through its direct interactions with SERCA2 and triadin, mediating a fine cross talk between SR Ca uptake and release in the heart. | Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase. Arvanitis DA, Vafiadaki E, Fan GC, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Sanoudou D, Kranias EG. | 01/21/2010 |
gene organization and cloning of the major isoform | Human skeletal muscle triadin: gene organization and cloning of the major isoform, Trisk 51. Thevenon D, Smida-Rezgui S, Chevessier F, Groh S, Henry-Berger J, Beatriz Romero N, Villaz M, DeWaard M, Marty I. | 01/21/2010 |