The RNA helicase DDX21 activates YAP to promote tumorigenesis and is transcriptionally upregulated by beta-catenin in colorectal cancer. | The RNA helicase DDX21 activates YAP to promote tumorigenesis and is transcriptionally upregulated by β-catenin in colorectal cancer. Tang W, Yang Y, Fu Z, Xu W, Ou W, Liu F, Du P, Liu CY., Free PMC Article | 11/7/2024 |
SENP3 mediates the deSUMOylation and degradation of YAP1 to regulate the progression of triple-negative breast cancer. | SENP3 mediates the deSUMOylation and degradation of YAP1 to regulate the progression of triple-negative breast cancer. Chen X, Li D, Su Q, Ling X, Yang Y, Liu Y, Zhu X, He A, Ding S, Xu R, Liu Z, Long X, Zhang J, Yang Z, Qi Y, Wu H., Free PMC Article | 11/7/2024 |
Circ_0002722-induced regulation of YAP promotes platinum resistance in oral squamous cell carcinoma: Implications for verteporfin therapy. | Circ_0002722-induced regulation of YAP promotes platinum resistance in oral squamous cell carcinoma: Implications for verteporfin therapy. Tsai HC, Tsai MH, Hua CH, Huang CW, Lu CC, Chen KJ, Yuan-Chien Chen M, Lien MY, Tang CH. | 11/4/2024 |
Arp2/3 complex activity enables nuclear YAP for naive pluripotency of human embryonic stem cells. | Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells. Meyer NP, Singh T, Kutys ML, Nystul TG, Barber DL., Free PMC Article | 11/4/2024 |
HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14. | HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14. Blakely WJ, Hatterschide J, White EA., Free PMC Article | 10/29/2024 |
Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and Tumorigenesis. | Ku70 Binding to YAP Alters PARP1 Ubiquitination to Regulate Genome Stability and Tumorigenesis. Shu Y, Jin X, Ji M, Zhang Z, Wang X, Liang H, Lu S, Dong S, Lin Y, Guo Y, Zhuang Q, Wang Y, Lei Z, Guo L, Meng X, Zhou G, Zhang W, Chang L. | 10/25/2024 |
EIF4A3-Induced Upregulation of hsa_circ_0049396 Attenuates the Tumorigenesis of Nasopharyngeal Carcinoma by Regulating the Hippo-YAP Pathway. | EIF4A3-Induced Upregulation of hsa_circ_0049396 Attenuates the Tumorigenesis of Nasopharyngeal Carcinoma by Regulating the Hippo-YAP Pathway. Zhou Q, Cai B, Liu K, Chen H. | 10/25/2024 |
LncRNA HOTAIR promotes the migration and invasion of cervical cancer through DNMT3B/LATS1/ YAP1 pS127 axis. | LncRNA HOTAIR promotes the migration and invasion of cervical cancer through DNMT3B/LATS1/ YAP1 pS127 axis. Zhang Z, Zhou X, Li J, Meng Q, Zheng P. | 10/22/2024 |
HPV-YAP1 oncogenic alliance drives malignant transformation of fallopian tube epithelial cells. | HPV-YAP1 oncogenic alliance drives malignant transformation of fallopian tube epithelial cells. He C, Lv X, Liu J, Ruan J, Chen P, Huang C, Angeletti PC, Hua G, Moness ML, Shi D, Dhar A, Yang S, Murphy S, Montoute I, Chen X, Islam KN, George S, Ince TA, Drapkin R, Guda C, Davis JS, Wang C., Free PMC Article | 10/21/2024 |
Targeting YAP Activity and Glutamine Metabolism Cooperatively Suppresses Tumor Progression by Preventing Extracellular Matrix Accumulation. | Targeting YAP Activity and Glutamine Metabolism Cooperatively Suppresses Tumor Progression by Preventing Extracellular Matrix Accumulation. Park M, Jin J, An DY, Kim DH, Lee J, Yun JW, Hwang I, Park JS, Kim MK, Lee YM, Byun JK, Choi YK, Park KG. | 10/20/2024 |
A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth. | A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth. Kurlishchuk Y, Cindric Vranesic A, Jessen M, Kipping A, Ritter C, Kim K, Cramer P, von Eyss B., Free PMC Article | 10/20/2024 |
TRIM65/NF2/YAP1 Signaling Coordinately Orchestrates Metabolic and Immune Advantages in Hepatocellular Carcinoma. | TRIM65/NF2/YAP1 Signaling Coordinately Orchestrates Metabolic and Immune Advantages in Hepatocellular Carcinoma. Bian Z, Xu C, Wang X, Zhang B, Xiao Y, Liu L, Zhao S, Huang N, Yang F, Zhang Y, Xue S, Wang X, Pan Q, Sun F., Free PMC Article | 10/3/2024 |
Lumbar instability remodels cartilage endplate to induce intervertebral disc degeneration by recruiting osteoclasts via Hippo-CCL3 signaling. | Lumbar instability remodels cartilage endplate to induce intervertebral disc degeneration by recruiting osteoclasts via Hippo-CCL3 signaling. Li H, Tang Y, Liu Z, Chen K, Zhang K, Hu S, Pan C, Yang H, Li B, Chen H., Free PMC Article | 09/20/2024 |
KAT6A/YAP/TEAD4 pathway modulates osteoclastogenesis by regulating the RANKL/OPG ratio on the compression side during orthodontic tooth movement. | KAT6A/YAP/TEAD4 pathway modulates osteoclastogenesis by regulating the RANKL/OPG ratio on the compression side during orthodontic tooth movement. Tan K, Wang J, Su X, Zheng Y, Li W., Free PMC Article | 09/19/2024 |
CRKL Enhances YAP Signaling through Binding and JNK/JUN Pathway Activation in Liver Cancer. | CRKL Enhances YAP Signaling through Binding and JNK/JUN Pathway Activation in Liver Cancer. Wesener MC, Weiler SME, Bissinger M, Klessinger TF, Rose F, Merker S, Luzarowski M, Ruppert T, Helm B, Klingmüller U, Schirmacher P, Breuhahn K., Free PMC Article | 09/19/2024 |
YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis. | YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis. Su W, Guo Y, Wang Q, Ma L, Zhang Q, Zhang Y, Geng Y, Jin T, Guo J, Yang R, Niu Z, Ren L, Wang Y, Ning Z, Li W, He W, Sun J, Li T, Li Z, Shan H, Liang H., Free PMC Article | 09/12/2024 |
YAP1-induced RBM24 promotes the tumorigenesis of triple-negative breast cancer through the beta-catenin pathway. | YAP1-induced RBM24 promotes the tumorigenesis of triple-negative breast cancer through the β-catenin pathway. Chen X, Lin X, Xia X, Xiang X. | 09/5/2024 |
YAP/TAZ-TEAD activity promotes the malignant transformation of cervical intraepithelial neoplasia through enhancing the characteristics and Warburg effect of cancer stem cells. | YAP/TAZ-TEAD activity promotes the malignant transformation of cervical intraepithelial neoplasia through enhancing the characteristics and Warburg effect of cancer stem cells. Li S, Li X, Yang YB, Wu SF., Free PMC Article | 08/21/2024 |
Complex interplay between RAS GTPases and RASSF effectors regulates subcellular localization of YAP. | Complex interplay between RAS GTPases and RASSF effectors regulates subcellular localization of YAP. Singh S, Bernal Astrain G, Hincapie AM, Goudreault M, Smith MJ., Free PMC Article | 08/21/2024 |
The miRNAs 203a/210-3p/5001-5p regulate the androgen/androgen receptor/YAP-induced migration in prostate cancer cells. | The miRNAs 203a/210-3p/5001-5p regulate the androgen/androgen receptor/YAP-induced migration in prostate cancer cells. Huo C, Kuo YY, Lin CY, Shiah SG, Li CY, Huang SP, Chen JK, Wang WC, Kung HJ, Chuu CP., Free PMC Article | 08/20/2024 |
Nuclear Localization of Yes-Associated Protein Is Associated With Tumor Progression in Cutaneous Melanoma. | Nuclear Localization of Yes-Associated Protein Is Associated With Tumor Progression in Cutaneous Melanoma. Ryu HJ, Kim C, Jang H, Kim SI, Shin SJ, Chung KY, Torres-Cabala C, Kim SK. | 08/12/2024 |
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer. | The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer. Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W. | 08/9/2024 |
The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer. | The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer. Patterson MR, Cogan JA, Cassidy R, Theobald DA, Wang M, Scarth JA, Anene CA, Whitehouse A, Morgan EL, Macdonald A., Free PMC Article | 08/2/2024 |
Characterization of spinal hemangioblastomas in patients with and without von Hippel-Lindau, and YAP expression. | Characterization of spinal hemangioblastomas in patients with and without von Hippel-Lindau, and YAP expression. Calderón-Garcidueñas AL, Piña-Ballantyne SA, Espinosa-Aguilar EJ, de Jesús Ramos-Sánchez R. | 08/1/2024 |
The basement membrane regulates the cellular localization and the cytoplasmic interactome of Yes-Associated Protein (YAP) in mammary epithelial cells. | The basement membrane regulates the cellular localization and the cytoplasmic interactome of Yes-Associated Protein (YAP) in mammary epithelial cells. Manucci AC, Fiore APZP, Genesi GL, Bruni-Cardoso A. | 08/1/2024 |