| SPON1 is an independent prognostic biomarker for ovarian cancer. | SPON1 is an independent prognostic biomarker for ovarian cancer.
Miyakawa R, Kobayashi M, Sugimoto K, Endo Y, Kojima M, Kobayashi Y, Furukawa S, Honda T, Watanabe T, Asano S, Soeda S, Hashimoto Y, Fujimori K, Chiba H., Free PMC Article | 05/15/2023 |
| Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL-6 trans-signalling. | Increased SPON1 promotes pancreatic ductal adenocarcinoma progression by enhancing IL-6 trans-signalling.
Huo Y, Yang J, Zheng J, Xu D, Yang M, Tao L, Yao H, Fu X, Yang J, Liu D, Hua R, Zhang J, Sun Y, Hu L, Liu W., Free PMC Article | 06/11/2022 |
| Prognostic and Diagnostic Values of miR-506 and SPON 1 in Colorectal Cancer with Clinicopathological Considerations. | Prognostic and Diagnostic Values of miR-506 and SPON 1 in Colorectal Cancer with Clinicopathological Considerations.
Tamjidifar R, Akbari M, Tarzi S, Sadeghzadeh M, Abolghasemi M, Poursaei E, Shomali N, Mahdavi F. | 06/26/2021 |
| Evaluation of relationship between SPON1 gene and genetic susceptibility of postmenopausal osteoporosis. | Evaluation of relationship between SPON1 gene and genetic susceptibility of postmenopausal osteoporosis.
Ma W, Chen K, Xiao W, Tang H, Wang S, Wang K. | 03/27/2021 |
| SPON1 rs2618516 polymorphism moderated the effects of APOE on working memory in terms of both in behaviors and in the level of brain activations. | APOE influences working memory in non-demented elderly through an interaction with SPON1 rs2618516.
Liu Z, Dai X, Tao W, Liu H, Li H, Yang C, Zhang J, Li X, Chen Y, Ma C, Pei J, Mao H, Chen K, Zhang Z., Free PMC Article | 04/20/2019 |
| gene expression experiment revealed that CYP2B6, SPON1, and GSG1L can be activated concomitantly through a constitutive androstane receptor (CAR) activation pathway | Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients.
Yang HC, Chu SK, Huang CL, Kuo HW, Wang SC, Liu SW, Ho IK, Liu YL., Free PMC Article | 08/13/2016 |
| SPON1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma. | Spondin 1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma.
Chang H, Dong T, Ma X, Zhang T, Chen Z, Yang Z, Zhang Y. | 10/3/2015 |
| These data suggest that SPON1 may be associated with the differential rate of cognitive decline in Alzheimer disease. | Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A, Green RC, GENAROAD Consortium, Alzheimer's Disease Neuroimaging Initiative, Alzheimer's Disease Genetics Consortium., Free PMC Article | 08/16/2014 |
| High SPON1 expression is associated with high-grade gliomas. | Experimental validation of 5 in-silico predicted glioma biomarkers.
Towner RA, Jensen RL, Vaillant B, Colman H, Saunders D, Giles CB, Wren JD., Free PMC Article | 07/12/2014 |
| Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity | Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity.
Jahanshad N, Rajagopalan P, Hua X, Hibar DP, Nir TM, Toga AW, Jack CR Jr, Saykin AJ, Green RC, Weiner MW, Medland SE, Montgomery GW, Hansell NK, McMahon KL, de Zubicaray GI, Martin NG, Wright MJ, Thompson PM, Alzheimer’s Disease Neuroimaging Initiative., Free PMC Article | 05/25/2013 |
| downregulates osteoclast recruitment to the root side of periodontal tissue via low-density lipoprotein receptor-related protein 8 and inhibits differentiation of osteoclastic precursors | F-spondin inhibits migration and differentiation of osteoclastic precursors.
Oka H, Mori M, Kihara H. | 04/14/2012 |
| These findings indicate that F-spondin regulates the differentiation of human cementoblast-like cells via BMP7 expression. | F-spondin regulates the differentiation of human cementoblast-like (HCEM) cells via BMP7 expression.
Kitagawa M, Ao M, Miyauchi M, Abiko Y, Takata T. | 04/14/2012 |
| The unique feature of F-spondin FS domain is the presence of three disulfide bonds associated with the N- and C-termini of the domain and a highly conserved N-linked glycosylation site. | The structure of the Ca²+-binding, glycosylated F-spondin domain of F-spondin - A C2-domain variant in an extracellular matrix protein.
Tan K, Lawler J., Free PMC Article | 10/1/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| These studies identify F-spondin as a novel protein in osteoarthritis cartilage, where it may act in situ at lesional areas to activate latent TGF-beta and induce cartilage degradation. | F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TGF-beta activation.
Attur MG, Palmer GD, Al-Mussawir HE, Dave M, Teixeira CC, Rifkin DB, Appleton CT, Beier F, Abramson SB., Free PMC Article | 01/21/2010 |
| The crystal structure of the reelin-N domain resolved to 2.0 A reveals a variant immunoglobulin-like fold and potential heparin-binding sites. | The crystal structure of the heparin-binding reelin-N domain of f-spondin.
Tan K, Duquette M, Liu JH, Lawler J, Wang JH., Free PMC Article | 01/21/2010 |
| identified F-spondin as a promoting factor for cementoblastic differentiation | Effect of F-spondin on cementoblastic differentiation of human periodontal ligament cells.
Kitagawa M, Kudo Y, Iizuka S, Ogawa I, Abiko Y, Miyauchi M, Takata T. | 01/21/2010 |
| expression profile of VSGP/F-spondin identifies this molecule as a potential diagnostic marker or target for developing therapeutic strategies to treat ovarian carcinoma | VSGP/F-spondin: a new ovarian cancer marker.
Pyle-Chenault RA, Stolk JA, Molesh DA, Boyle-Harlan D, McNeill PD, Repasky EA, Jiang Z, Fanger GR, Xu J. | 01/21/2010 |