Energy stress promotes P-bodies formation via lysine-63-linked polyubiquitination of HAX1.
Zhan W, Li Z, Zhang J, Liu Y, Liu G, Li B, Shen R, Jiang Y, Shang W, Gao S, Wu H, Wang Y, Chen W, Wang Z., Free PMC Article

The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression.
Jin H, Huang X, Pan Q, Ma N, Xie X, Wei Y, Yu F, Wen W, Zhang B, Zhang P, Chen X, Wang J, Liu RY, Lin J, Meng X, Lee MH., Free PMC Article

HAX1 is a novel binding partner of Che-1/AATF. Implications in oxidative stress cell response.
Pisani C, Onori A, Gabanella F, Iezzi S, De Angelis R, Fanciulli M, Colizza A, de Vincentiis M, Di Certo MG, Passananti C, Corbi N.

NOD1 cooperates with HAX-1 to promote cell migration in a RIPK2- and NF-ĸB-independent manner.
Hezinger L, Bauer S, Ellwanger K, Piotrowsky A, Biber F, Venturelli S, Kufer TA.

HAX1-related congenital neutropenia: Long-term observation in paediatric and adult patients enrolled in the European branch of the Severe Chronic Neutropenia International Registry (SCNIR).
Pogozhykh D, Yilmaz Karapinar D, Klimiankou M, Gerschmann N, Ebetsberger-Dachs G, Palmblad J, Carlsson G, Masmas T, Kinsey S, Bartels M, Mellor-Heineke S, Welte K, Skokowa J, Zeidler C.

Effect of different expression patterns of HAX-1 on the proliferation and apoptosis of human astrocyte.
Xia X, Zhu X, Zhang S, Zhang X, Wang Y.

Hsa-miR223-3p circulating level is upregulated in Friedreich's ataxia and inversely associated with HCLS1 associated protein X-1, HAX-1.
Quatrana A, Morini E, Tiano F, Vancheri C, Panarello L, Romano S, Marcotulli C, Casali C, Mariotti C, Mongelli A, Fichera M, Rufini A, Condò I, Novelli G, Testi R, Amati F, Malisan F.

Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation.
You B, Pan S, Gu M, Zhang K, Xia T, Zhang S, Chen W, Xie H, Fan Y, Yao H, Cheng T, Zhang P, Liu D, You Y., Free PMC Article

HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation.
Fan Y, Murgia M, Linder MI, Mizoguchi Y, Wang C, Łyszkiewicz M, Ziȩtara N, Liu Y, Frenz S, Sciuccati G, Partida-Gaytan A, Alizadeh Z, Rezaei N, Rehling P, Dennerlein S, Mann M, Klein C., Free PMC Article

HAX1 maintains the glioma progression in hypoxia through promoting mitochondrial fission.
Lin J, Wang Y, Lin Z., Free PMC Article

A Novel Intronic Mutation Reduces HAX1 Level and is Associated With Severe Congenital Neutropenia.
Goktas S, Azizoglu ZB, Petersheim D, Erdogan M, Eke Gungor H, Bisgin A, Tuğ Bozdoğan S, Eken A, Unal E, Klein C, Patiroglu T.

Sanguisorba parviflora (Maxim.) Takeda alleviates cyclophosphamide-induced leukopenia by regulating haematopoietic cell-specific protein 1-associated protein X-1 gene expression.
Meng L, Li J, Meng X, Zhou Y, Wang J, Liu S, Zhao Y.

Sanguisorba parviflora (Maxim) Takeda alleviates cyclophosphamide-induced leukopenia via regulating the hematopoietic cell-specific protein 1-associated protein X-1 gene.
Meng L, Li J, Meng X, Zhou Y, Wang J, Liu S, Zhao Y.

HTLV-1 viral oncoprotein HBZ contributes to the enhancement of HAX-1 stability by impairing the ubiquitination pathway.
Tanaka Y, Mukai R, Ohshima T.

HAX1 enhances the survival and metastasis of non-small cell lung cancer through the AKT/mTOR and MDM2/p53 signaling pathway.
Liang Z, Zhong Y, Meng L, Chen Y, Liu Y, Wu A, Li X, Wang M., Free PMC Article

A zebrafish model for HAX1-associated congenital neutropenia.
Doll L, Aghaallaei N, Dick AM, Welte K, Skokowa J, Bajoghli B., Free PMC Article

MicroRNA‑125a‑5p regulates liver cancer cell growth, migration and invasion and EMT by targeting HAX1.
Zha Z, Li J., Free PMC Article

Accumulation of HAX-1 and PARL in brainstem- and cortical-type Lewy bodies in Parkinson's disease and dementia with Lewy bodies.
Kawamoto Y, Ayaki T, Urushitani M, Ito H, Takahashi R.

Identification of protein/mRNA network involving the PSORS1 locus gene CCHCR1 and the PSORS4 locus gene HAX1.
Pisani C, Onori A, Gabanella F, Di Certo MG, Passananti C, Corbi N.

Frataxin deficiency in Friedreich's ataxia is associated with reduced levels of HAX-1, a regulator of cardiomyocyte death and survival.
Tiano F, Amati F, Cherubini F, Morini E, Vancheri C, Maletta S, Fortuni S, Serio D, Quatrana A, Luffarelli R, Benini M, Alfedi G, Panarello L, Rufini A, Toschi N, Frontali M, Romano S, Marcotulli C, Casali C, Gioiosa S, Mariotti C, Mongelli A, Fichera M, Condò I, Novelli G, Testi R, Malisan F.

Suppression of HAX-1 induced by miR-325 resensitizes bladder cancer cells to cisplatin-induced apoptosis.
Li R, Zheng JZ, Huang X.

The interactome of multifunctional HAX1 protein suggests its role in the regulation of energy metabolism, de-aggregation, cytoskeleton organization and RNA-processing.
Wakula M, Balcerak A, Rubel T, Chmielarczyk M, Konopinski R, Lyczek F, Grzybowska EA., Free PMC Article

miR-125b suppresses cell proliferation and metastasis by targeting HAX-1 in esophageal squamous cell carcinoma.
Yu Z, Ni F, Chen Y, Zhang J, Cai J, Shi W.

miR-654-5p Targets HAX-1 to Regulate the Malignancy Behaviors of Colorectal Cancer Cells.
Huang F, Wu X, Wei M, Guo H, Li H, Shao Z, Wu Y, Pu J., Free PMC Article

Structural modeling and role of HAX-1 as a positive allosteric modulator of human serine protease HtrA2.
Chaganti LK, Dutta S, Kuppili RR, Mandal M, Bose K.