The Important Role of Phosphatidylserine, ADAM17, TNF-Alpha, and Soluble MER on Efferocytosis Activity in Central Obesity. | The Important Role of Phosphatidylserine, ADAM17, TNF-Alpha, and Soluble MER on Efferocytosis Activity in Central Obesity. Purnama CA, Meiliana A, Barliana MI, Lestari K, Wijaya A., Free PMC Article | 04/3/2024 |
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. | Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. Nerviani A, Boutet MA, Ghirardi GM, Goldmann K, Sciacca E, Rivellese F, Pontarini E, Prediletto E, Abatecola F, Caliste M, Pagani S, Mauro D, Bellan M, Cubuk C, Lau R, Church SE, Hudson BM, Humby F, Bombardieri M, Lewis MJ, Pitzalis C., Free PMC Article | 03/18/2024 |
Semaphorin3B promotes an anti-inflammatory and pro-resolving phenotype in macrophages from rheumatoid arthritis patients in a MerTK-dependent manner. | Semaphorin3B promotes an anti-inflammatory and pro-resolving phenotype in macrophages from rheumatoid arthritis patients in a MerTK-dependent manner. Martínez-Ramos S, Rafael-Vidal C, Malvar-Fernández B, Pérez N, Mouriño C, Pérez SG, Maceiras Pan FJ, Conde C, Pego-Reigosa JM, García S., Free PMC Article | 03/1/2024 |
Big data analytics for MerTK genomics reveals its double-edged sword functions in human diseases. | Big data analytics for MerTK genomics reveals its double-edged sword functions in human diseases. Liu S, Wu J, Yang D, Xu J, Shi H, Xue B, Ding Z., Free PMC Article | 02/28/2024 |
Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma. | Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma. Wang S, Zhu L, Li T, Lin X, Zheng Y, Xu D, Guo Y, Zhang Z, Fu Y, Wang H, Wang X, Zou T, Shen X, Zhang L, Lai N, Lu L, Qin L, Dong Q., Free PMC Article | 02/26/2024 |
MerTK is a mediator of alpha-synuclein fibril uptake by human microglia. | MerTK is a mediator of alpha-synuclein fibril uptake by human microglia. Dorion MF, Yaqubi M, Senkevich K, Kieran NW, MacDonald A, Chen CXQ, Luo W, Wallis A, Shlaifer I, Hall JA, Dudley RWR, Glass IA, Birth Defects Research Laboratory, Stratton JA, Fon EA, Bartels T, Antel JP, Gan-Or Z, Durcan TM, Healy LM., Free PMC Article | 02/7/2024 |
HLA-DRB1*15:01 and the MERTK Gene Interact to Selectively Influence the Profile of MERTK-Expressing Monocytes in Both Health and MS. | HLA-DRB1*15:01 and the MERTK Gene Interact to Selectively Influence the Profile of MERTK-Expressing Monocytes in Both Health and MS. Binder MD, Nwoke EC, Morwitch E, Dwyer C, Li V, Xavier A, Lea RA, Lechner-Scott J, Taylor BV, Ponsonby AL, Kilpatrick TJ, Ausimmune Investigator Group., Free PMC Article | 01/5/2024 |
Regulation of brain endothelial cell physiology by the TAM receptor tyrosine kinase Mer. | Regulation of brain endothelial cell physiology by the TAM receptor tyrosine kinase Mer. Happonen KE, Burrola PG, Lemke G., Free PMC Article | 09/8/2023 |
Elevated expression of macrophage MERTK exhibits profibrotic effects and results in defective regulation of efferocytosis function in pulmonary fibrosis. | Elevated expression of macrophage MERTK exhibits profibrotic effects and results in defective regulation of efferocytosis function in pulmonary fibrosis. She Y, Xu X, Yu Q, Yang X, He J, Tang XX., Free PMC Article | 08/25/2023 |
MERTK missense variants in three patients with retinitis pigmentosa. | MERTK missense variants in three patients with retinitis pigmentosa. Poli FE, Yusuf IH, Clouston P, Shanks M, Whitfield J, Charbel Issa P, MacLaren RE., Free PMC Article | 02/24/2023 |
Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease. | Mer-tyrosine kinase: a novel susceptibility gene for SLE related end-stage renal disease. Yavuz S, Pucholt P, Sandling JK, Bianchi M, Leonard D, Bolin K, Imgenberg-Kreuz J, Eloranta ML, Kozyrev SV, Lanata CM, Jönsen A, Bengtsson AA, Sjöwall C, Svenungsson E, Gunnarsson I, Rantapää-Dahlqvist S, ImmunoArray Development Consortium, DISSECT Consortium, Nititham J, Criswell LA, Lindblad-Toh K, Rönnblom L., Free PMC Article | 11/12/2022 |
Mer Tyrosine Kinase (MERTK) modulates liver fibrosis progression and hepatocellular carcinoma development. | Mer Tyrosine Kinase (MERTK) modulates liver fibrosis progression and hepatocellular carcinoma development. Pipitone RM, Calvaruso V, Di Marco L, Di Salvo F, Gaggianesi M, Lupo G, Zito R, La Mantia C, Ramazzotti M, Petta S, Di Marco V, Craxì A, Grimaudo S., Free PMC Article | 09/3/2022 |
Mertk: An emerging target in cancer biology and immuno-oncology. | Mertk: An emerging target in cancer biology and immuno-oncology. Lahey KC, Gadiyar V, Hill A, Desind S, Wang Z, Davra V, Patel R, Zaman A, Calianese D, Birge RB., Free PMC Article | 06/18/2022 |
High Glucose Impairs Expression and Activation of MerTK in ARPE-19 Cells. | High Glucose Impairs Expression and Activation of MerTK in ARPE-19 Cells. Puddu A, Ravera S, Panfoli I, Bertola N, Maggi D., Free PMC Article | 03/12/2022 |
Differential polarization and the expression of efferocytosis receptor MerTK on M1 and M2 macrophages isolated from coronary artery disease patients. | Differential polarization and the expression of efferocytosis receptor MerTK on M1 and M2 macrophages isolated from coronary artery disease patients. Mohd Idrus FN, Ahmad NS, Hoe CH, Azlan M, Norfuad FA, Yusof Z, Wan Isa WYH, Mohamed Ali AA, Yvonne-Tee GB., Free PMC Article | 02/19/2022 |
MerTK-mediated efferocytosis promotes immune tolerance and tumor progression in osteosarcoma through enhancing M2 polarization and PD-L1 expression. | MerTK-mediated efferocytosis promotes immune tolerance and tumor progression in osteosarcoma through enhancing M2 polarization and PD-L1 expression. Lin J, Xu A, Jin J, Zhang M, Lou J, Qian C, Zhu J, Wang Y, Yang Z, Li X, Yu W, Liu B, Tao H., Free PMC Article | 02/5/2022 |
MERTK retinopathy: biomarkers assessing vision loss. | MERTK retinopathy: biomarkers assessing vision loss. Sakti DH, Cornish EE, Mustafic N, Zaheer A, Retsas S, Rajagopalan S, Chung CW, Ewans L, McCluskey P, Nash BM, Jamieson RV, Grigg JR. | 02/5/2022 |
Mer tyrosine kinase as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease. | Mer tyrosine kinase as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease. Rovati L, Kaneko N, Pedica F, Monno A, Maehara T, Perugino C, Lanzillotta M, Pecetta S, Stone JH, Doglioni C, Manfredi AA, Pillai S, Della-Torre E., Free PMC Article | 01/1/2022 |
MERTK on mononuclear phagocytes regulates T cell antigen recognition at autoimmune and tumor sites. | MERTK on mononuclear phagocytes regulates T cell antigen recognition at autoimmune and tumor sites. Lindsay RS, Whitesell JC, Dew KE, Rodriguez E, Sandor AM, Tracy D, Yannacone SF, Basta BN, Jacobelli J, Friedman RS., Free PMC Article | 12/4/2021 |
MERTK-Mediated LC3-Associated Phagocytosis (LAP) of Apoptotic Substrates in Blood-Separated Tissues: Retina, Testis, Ovarian Follicles. | MERTK-Mediated LC3-Associated Phagocytosis (LAP) of Apoptotic Substrates in Blood-Separated Tissues: Retina, Testis, Ovarian Follicles. Yefimova MG, Ravel C, Rolland AD, Bourmeyster N, Jégou B., Free PMC Article | 11/6/2021 |
Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target. | Role of the Gas6/TAM System as a Disease Marker and Potential Drug Target. Sainaghi PP, Bellan M, Nerviani A., Free PMC Article | 10/30/2021 |
Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages. | Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages. Wanke F, Gutbier S, Rümmelin A, Steinberg M, Hughes LD, Koenen M, Komuczki J, Regan-Komito D, Wagage S, Hesselmann J, Thoma R, Brugger D, Christopeit T, Wang H, Point F, Hallet R, Ghosh S, Rothlin CV, Patsch C, Geering B., Free PMC Article | 09/25/2021 |
Immunological role of TAM receptors in the cancer microenvironment. | Immunological role of TAM receptors in the cancer microenvironment. Gadiyar V, Patel G, Davra V. | 09/4/2021 |
Post-translational modifications of the ligands: Requirement for TAM receptor activation. | Post-translational modifications of the ligands: Requirement for TAM receptor activation. Geng K. | 09/4/2021 |
TAM receptors and their ligand-mediated activation: Role in atherosclerosis. | TAM receptors and their ligand-mediated activation: Role in atherosclerosis. Cai B, Kasikara C., Free PMC Article | 09/4/2021 |