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    CARM1 coactivator associated arginine methyltransferase 1 [ Homo sapiens (human) ]

    Gene ID: 10498, updated on 15-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The emerging role of CARM1 in cancer.

    The emerging role of CARM1 in cancer.
    Xie Z, Tian Y, Guo X, Xie N., Free PMC Article

    10/15/2024
    CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A.

    CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A.
    Feng D, Gao J, Liu R, Liu W, Gao T, Yang Y, Zhang D, Yang T, Yin X, Yu H, Huang W, Wang Y., Free PMC Article

    10/8/2024
    CARM1 phosphorylation at S595 by p38gamma MAPK drives ROS-mediated cellular senescence.

    CARM1 phosphorylation at S595 by p38γ MAPK drives ROS-mediated cellular senescence.
    Cho Y, Kim YK., Free PMC Article

    10/7/2024
    CARM1 hypermethylates the NuRD chromatin remodeling complex to promote cell cycle gene expression and breast cancer development.

    CARM1 hypermethylates the NuRD chromatin remodeling complex to promote cell cycle gene expression and breast cancer development.
    Chen X, Huang MF, Fan DM, He YH, Zhang WJ, Ding JC, Peng BL, Pan X, Liu Y, Du J, Li Y, Liu ZY, Xie BL, Kuang ZJ, Yi J, Liu W., Free PMC Article

    08/1/2024
    Protein Arginine Methyltransferase CARM1 in Human Breast Cancer.

    Protein Arginine Methyltransferase CARM1 in Human Breast Cancer.
    Bacabac M, Liu P, Xu W.,

    07/28/2024
    Trans-Activation of the Coactivator-Associated Arginine Methyltransferase 1 (Carm1) Gene by the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1.

    Trans-Activation of the Coactivator-Associated Arginine Methyltransferase 1 (Carm1) Gene by the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1.
    Hayati RF, Nakajima R, Zhou Y, Shirasawa M, Zhao L, Fikriyanti M, Iwanaga R, Bradford AP, Kurayoshi K, Araki K, Ohtani K., Free PMC Article

    07/17/2024
    Epigenetic Regulation of Cardiomyocyte Maturation by Arginine Methyltransferase CARM1.

    Epigenetic Regulation of Cardiomyocyte Maturation by Arginine Methyltransferase CARM1.
    Garbutt TA, Wang Z, Wang H, Ma H, Ruan H, Dong Y, Xie Y, Tan L, Phookan R, Stouffer JA, Vedantham V, Yang Y, Qian L, Liu J.,

    05/31/2024
    Tyrosine phosphorylation of CARM1 promotes its enzymatic activity and alters its target specificity.

    Tyrosine phosphorylation of CARM1 promotes its enzymatic activity and alters its target specificity.
    Itonaga H, Mookhtiar AK, Greenblatt SM, Liu F, Martinez C, Bilbao D, Rains M, Hamard PJ, Sun J, Umeano AC, Duffort S, Chen C, Man N, Mas G, Tottone L, Totiger T, Bradley T, Taylor J, Schürer S, Nimer SD., Free PMC Article

    05/7/2024
    BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17.

    BACH1 regulates the differentiation of vascular smooth muscle cells from human embryonic stem cells via CARM1-mediated methylation of H3R17.
    He Y, Guo J, Yu Y, Jin J, Jiang Q, Li Q, Ma S, Pan Q, Lin J, Jiang N, Ma J, Li Y, Hou Y, Zhi X, Jiang L, Qu L, Osto E, Wang X, Wei X, Meng D.

    01/5/2024
    Inhibition of CARM1 suppresses proliferation of multiple myeloma cells through activation of p53 signaling pathway.

    Inhibition of CARM1 suppresses proliferation of multiple myeloma cells through activation of p53 signaling pathway.
    Yang L, Ma L, Gong Q, Chen J, Huang Q., Free PMC Article

    08/30/2023
    PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARgamma.

    PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ.
    Zhong Y, Wang Y, Li X, Qin H, Yan S, Rao C, Fan D, Liu D, Deng F, Miao Y, Yang L, Huang K., Free PMC Article

    08/1/2023
    Carm1-arginine methylation of the transcription factor C/EBPalpha regulates transdifferentiation velocity.

    Carm1-arginine methylation of the transcription factor C/EBPα regulates transdifferentiation velocity.
    Torcal Garcia G, Kowenz-Leutz E, Tian TV, Klonizakis A, Lerner J, De Andres-Aguayo L, Sapozhnikova V, Berenguer C, Carmona MP, Casadesus MV, Bulteau R, Francesconi M, Peiro S, Mertins P, Zaret K, Leutz A, Graf T., Free PMC Article

    07/5/2023
    Unraveling the complexity of histone-arginine methyltransferase CARM1 in cancer: From underlying mechanisms to targeted therapeutics.

    Unraveling the complexity of histone-arginine methyltransferase CARM1 in cancer: From underlying mechanisms to targeted therapeutics.
    Jin W, Zhang J, Chen X, Yin S, Yu H, Gao F, Yao D.

    06/25/2023
    Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis.

    Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis.
    Lai Y, Li X, Li T, Li X, Nyunoya T, Chen K, Kitsios G, Nouraie M, Zhang Y, McVerry BJ, Lee JS, Mallmapalli RK, Zou C., Free PMC Article

    03/20/2023
    CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4beta.

    CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β.
    Cao Y, Chen Z, Qin Z, Qian K, Liu T, Zhang Y., Free PMC Article

    10/29/2022
    LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML.

    LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML.
    Chen Q, Cevher MA, Jiang Q, Wang S, Sun X, Roeder RG, Chen M., Free PMC Article

    10/15/2022
    Systematic pan-cancer landscape identifies CARM1 as a potential prognostic and immunological biomarker.

    Systematic pan-cancer landscape identifies CARM1 as a potential prognostic and immunological biomarker.
    Qiu Y, Wang H, Liao P, Xu B, Hu R, Yang Y, Li Y., Free PMC Article

    05/14/2022
    Histone arginine methyltransferase CARM1 selective inhibitor TP-064 induces apoptosis in endometrial cancer.

    Histone arginine methyltransferase CARM1 selective inhibitor TP-064 induces apoptosis in endometrial cancer.
    Inoue F, Sone K, Toyohara Y, Tanimoto S, Takahashi Y, Kusakabe M, Kukita A, Honjoh H, Nishijima A, Taguchi A, Miyamoto Y, Tanikawa M, Iriyama T, Uchino MM, Tsuruga T, Wada-Hiraike O, Oda K, Osuga Y.

    04/16/2022
    Protein arginine N-methyltransferase 1 gene polymorphism is associated with proliferative diabetic retinopathy in a Japanese population.

    Protein arginine N-methyltransferase 1 gene polymorphism is associated with proliferative diabetic retinopathy in a Japanese population.
    Iwasaki H, Shichiri M.

    02/26/2022
    Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia.

    Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia.
    Lai Y, Li X, Li T, Nyunoya T, Chen K, Kitsios GD, Nouraie SM, Zhang Y, McVerry BJ, Lee JS, Mallampalli RK, Zou C., Free PMC Article

    01/29/2022
    CARM1/PRMT4: Making Its Mark beyond Its Function as a Transcriptional Coactivator.

    CARM1/PRMT4: Making Its Mark beyond Its Function as a Transcriptional Coactivator.
    Suresh S, Huard S, Dubois T.

    12/11/2021
    Targeting the IRE1alpha/XBP1s pathway suppresses CARM1-expressing ovarian cancer.

    Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer.
    Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang CA, Wu S, Zhou W, Guo D, Karakashev S, Hu CA, Sarma K, Kossenkov AV, Zhang R., Free PMC Article

    10/9/2021
    A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes.

    A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes.
    Iyamu ID, Al-Hamashi AA, Huang R., Free PMC Article

    09/25/2021
    High Expression of CARM1 Inhibits Lung Cancer Progression by Targeting TP53 by Regulating CTNNB1.

    High Expression of CARM1 Inhibits Lung Cancer Progression by Targeting TP53 by Regulating CTNNB1.
    Hu B, Li X, Chen L, Liu Z.

    07/24/2021
    MiR-542-5p regulates the progression of diabetic retinopathy by targeting CARM1.

    MiR-542-5p regulates the progression of diabetic retinopathy by targeting CARM1.
    Guo N, Nulahou A, Bu Q, Liu M, Wang Y, Zhao Y, Yang L, Gao Y.

    07/10/2021
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