| SPIN1 facilitates chemoresistance and HR repair by promoting Tip60 binding to H3K9me3. | SPIN1 facilitates chemoresistance and HR repair by promoting Tip60 binding to H3K9me3.
Wang Y, Li M, Chen Y, Jiang Y, Zhang Z, Yan Z, Liu X, Wu C., Free PMC Article | 09/18/2024 |
| TIP60 acetylation of Bub1 regulates centromeric H2AT120 phosphorylation for faithful chromosome segregation. | TIP60 acetylation of Bub1 regulates centromeric H2AT120 phosphorylation for faithful chromosome segregation.
Sun M, Yang B, Xin G, Wang Y, Luo J, Jiang Q, Zhang C. | 09/9/2024 |
| The Tudor-knot Domain of KAT5 Regulates Nucleosomal Substrate Acetylation. | The Tudor-knot Domain of KAT5 Regulates Nucleosomal Substrate Acetylation.
Xuan F, Xuan H, Huang M, He W, Xu H, Shi X, Wen H., | 03/26/2024 |
| TIP60 is required for tumorigenesis in non-small cell lung cancer. | TIP60 is required for tumorigenesis in non-small cell lung cancer.
Shibahara D, Akanuma N, Kobayashi IS, Heo E, Ando M, Fujii M, Jiang F, Prin PN, Pan G, Wong KK, Costa DB, Bararia D, Tenen DG, Watanabe H, Kobayashi SS., Free PMC Article | 06/7/2023 |
| Acetylation of Nup62 by TIP60 ensures accurate chromosome segregation in mitosis. | Acetylation of Nup62 by TIP60 ensures accurate chromosome segregation in mitosis.
Akbar H, Cao J, Wang D, Yuan X, Zhang M, Muthusamy S, Song X, Liu X, Aikhionbare F, Yao X, Gao X, Liu X., Free PMC Article | 02/23/2023 |
| Investigation of mRNA Expression Levels of Tip60 and Related DNA Repair Genes in Molecular Subtypes of Breast Cancer. | Investigation of mRNA Expression Levels of Tip60 and Related DNA Repair Genes in Molecular Subtypes of Breast Cancer.
Miser-Salihoglu E, Demokan S, Karanlik H, Karahalil B, Önder S, Cömert S, Yardim-Akaydin S. | 02/11/2023 |
| A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans. | A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans.
Lu PYT, Kirlin AC, Aristizabal MJ, Brewis HT, Lévesque N, Setiaputra DT, Avvakumov N, Benschop JJ, Groot Koerkamp M, Holstege FCP, Krogan NJ, Yip CK, Côté J, Kobor MS., Free PMC Article | 11/12/2022 |
| Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation. | Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation.
Hong YJ, Park J, Hahm JY, Kim SH, Lee DH, Park KS, Seo SB., Free PMC Article | 10/22/2022 |
| Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest. | Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest.
Wichmann J, Pitt C, Eccles S, Garnham AL, Li-Wai-Suen CSN, May R, Allan E, Wilcox S, Herold MJ, Smyth GK, Monahan BJ, Thomas T, Voss AK., Free PMC Article | 07/30/2022 |
| TIP60 acts as a regulator of genes involved in filopodia formation and cell migration during wound healing. | TIP60 acts as a regulator of genes involved in filopodia formation and cell migration during wound healing.
Dubey S, Jaiswal B, Gupta A., Free PMC Article | 07/30/2022 |
| Vacuolar protein sorting-associated protein 72 homolog (VPS72) binding to lysine acetyltransferase 5 (KAT5) promotes the proliferation, invasion and migration of hepatocellular carcinoma through regulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway. | Vacuolar protein sorting-associated protein 72 homolog (VPS72) binding to lysine acetyltransferase 5 (KAT5) promotes the proliferation, invasion and migration of hepatocellular carcinoma through regulating phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) signaling pathway.
Chen T, Tu Y, Lv D, Lin K, Tang H, Huang W., Free PMC Article | 04/16/2022 |
| Circular RNA circRHOT1 contributes to pathogenesis of non-small cell lung cancer by epigenetically enhancing C-MYC expression through recruiting KAT5. | Circular RNA circRHOT1 contributes to pathogenesis of non-small cell lung cancer by epigenetically enhancing C-MYC expression through recruiting KAT5.
Ren X, Yu J, Guo L, Ma H., Free PMC Article | 02/5/2022 |
| TIP60 governs the autoubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex. | TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex.
Ahmad T, Ashraf W, Ibrahim A, Zaayter L, Muller CD, Hamiche A, Mély Y, Bronner C, Mousli M., Free PMC Article | 01/29/2022 |
| Ketamine suppresses proliferation and induces ferroptosis and apoptosis of breast cancer cells by targeting KAT5/GPX4 axis. | Ketamine suppresses proliferation and induces ferroptosis and apoptosis of breast cancer cells by targeting KAT5/GPX4 axis.
Li H, Liu W, Zhang X, Wu F, Sun D, Wang Z. | 01/8/2022 |
| Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia. | Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia.
Yamagata K, Shino M, Aikawa Y, Fujita S, Kitabayashi I. | 01/1/2022 |
| H2A.Z acetylation by lincZNF337-AS1 via KAT5 implicated in the transcriptional misregulation in cancer signaling pathway in hepatocellular carcinoma. | H2A.Z acetylation by lincZNF337-AS1 via KAT5 implicated in the transcriptional misregulation in cancer signaling pathway in hepatocellular carcinoma.
Yuan Y, Cao W, Zhou H, Qian H, Wang H., Free PMC Article | 11/6/2021 |
| TIP60/P400/H4K12ac Plays a Role as a Heterochromatin Back-up Skeleton in Breast Cancer. | TIP60/P400/H4K12ac Plays a Role as a Heterochromatin Back-up Skeleton in Breast Cancer.
Idrissou M, Boisnier T, Sanchez A, Khoufaf FZH, Penault-Llorca F, Bignon YJ, Bernard-Gallon D., Free PMC Article | 06/26/2021 |
| Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex. | Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.
Zhang H, Devoucoux M, Song X, Li L, Ayaz G, Cheng H, Tempel W, Dong C, Loppnau P, Côté J, Min J. | 04/13/2021 |
| Metabolic Roles of Androgen Receptor and Tip60 in Androgen-Dependent Prostate Cancer. | Metabolic Roles of Androgen Receptor and Tip60 in Androgen-Dependent Prostate Cancer.
Tan KN, Avery VM, Carrasco-Pozo C., Free PMC Article | 03/6/2021 |
| ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism. | ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.
Li J, Galbo PM Jr, Gong W, Storey AJ, Tsai YH, Yu X, Ahn JH, Guo Y, Mackintosh SG, Edmondson RD, Byrum SD, Farrar JE, He S, Cai L, Jin J, Tackett AJ, Zheng D, Wang GG., Free PMC Article | 02/27/2021 |
| Tip60 and p300 function antagonistically in the epigenetic regulation of HPV18 E6/E7 genes in cervical cancer HeLa cells. | Tip60 and p300 function antagonistically in the epigenetic regulation of HPV18 E6/E7 genes in cervical cancer HeLa cells.
Lai Y, He Z, Zhang A, Yan Z, Zhang X, Hu S, Wang N, He H. | 02/2/2021 |
| Isoform-Specific Lysine Methylation of RORalpha2 by SETD7 Is Required for Association of the TIP60 Coactivator Complex in Prostate Cancer Progression. | Isoform-Specific Lysine Methylation of RORα2 by SETD7 Is Required for Association of the TIP60 Coactivator Complex in Prostate Cancer Progression.
Song H, Chu JW, Park SC, Im H, Park IG, Kim H, Lee JM., Free PMC Article | 12/26/2020 |
| BRD8, which is negatively regulated by miR-876-3p, promotes the proliferation and apoptosis resistance of hepatocellular carcinoma cells via KAT5. | BRD8, which is negatively regulated by miR-876-3p, promotes the proliferation and apoptosis resistance of hepatocellular carcinoma cells via KAT5.
Yu Z, Chen T, Mo H, Guo C, Liu Q. | 12/26/2020 |
| Nuclear Localization Is Not Required for Tip60 Tumor Suppressor Activity in Breast and Lung Cancer Cells. | Nuclear Localization Is Not Required for Tip60 Tumor Suppressor Activity in Breast and Lung Cancer Cells.
Ravichandran P, Davis SA, Vashishtha H, Gucwa AL, Ginsburg DS. | 11/28/2020 |
| KAT5 acetylates cGAS to promote innate immune response to DNA virus. | KAT5 acetylates cGAS to promote innate immune response to DNA virus.
Song ZM, Lin H, Yi XM, Guo W, Hu MM, Shu HB., Free PMC Article | 11/21/2020 |