| miR-208a-3p regulated by circUQCRC2 suppresses ischemia/reperfusion-induced acute kidney injury by inhibiting CELF2-mediated tubular epithelial cell apoptosis, inflammation and ferroptosis. | miR-208a-3p regulated by circUQCRC2 suppresses ischemia/reperfusion-induced acute kidney injury by inhibiting CELF2-mediated tubular epithelial cell apoptosis, inflammation and ferroptosis.
Huang P, Meng L, Pang J, Huang H, Ma J, He L, Lin X. | 06/8/2024 |
| Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review). | Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review).
Li J, Xian L, Zhu Z, Wang Y, Zhang W, Zheng R, Xue W, Li J., Free PMC Article | 08/22/2023 |
| CircLIFR Inhibits Non-small Cell Lung Cancer Progression by Acting as a miR-429 Sponge to Enhance CELF2 Expression. | CircLIFR Inhibits Non-small Cell Lung Cancer Progression by Acting as a miR-429 Sponge to Enhance CELF2 Expression.
Wang J, Lai X, Peng X. | 04/6/2023 |
| Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA. | Hypoxia-induced lncRNA MRVI1-AS1 accelerates hepatocellular carcinoma progression by recruiting RNA-binding protein CELF2 to stabilize SKA1 mRNA.
Tuo H, Liu R, Wang Y, Yang W, Liu Q., Free PMC Article | 04/5/2023 |
| Natural Antisense Long Noncoding RNA HHIP-AS1 Suppresses Non-Small-Cell Lung Cancer Progression by Increasing HHIP Stability via Interaction with CELF2. | Natural Antisense Long Noncoding RNA HHIP-AS1 Suppresses Non-Small-Cell Lung Cancer Progression by Increasing HHIP Stability via Interaction with CELF2.
Yang Y, Cheng Y, Mou Y, Tang X, Mu X. | 11/19/2022 |
| MiR-210-3p targets CELF2 to facilitate progression of lung squamous carcinoma through PI3K/AKT pathway. | MiR-210-3p targets CELF2 to facilitate progression of lung squamous carcinoma through PI3K/AKT pathway.
Zhang Q, Wang Y. | 08/27/2022 |
| De novo variants in CELF2 that disrupt the nuclear localization signal cause developmental and epileptic encephalopathy. | De novo variants in CELF2 that disrupt the nuclear localization signal cause developmental and epileptic encephalopathy.
Itai T, Hamanaka K, Sasaki K, Wagner M, Kotzaeridou U, Brösse I, Ries M, Kobayashi Y, Tohyama J, Kato M, Ong WP, Chew HB, Rethanavelu K, Ranza E, Blanc X, Uchiyama Y, Tsuchida N, Fujita A, Azuma Y, Koshimizu E, Mizuguchi T, Takata A, Miyake N, Takahashi H, Miyagi E, Tsurusaki Y, Doi H, Taguri M, Antonarakis SE, Nakashima M, Saitsu H, Miyatake S, Matsumoto N. | 04/2/2022 |
| miR-363-3p induces EMT via the Wnt/beta-catenin pathway in glioma cells by targeting CELF2. | miR-363-3p induces EMT via the Wnt/β-catenin pathway in glioma cells by targeting CELF2.
Fan B, Su B, Song G, Liu X, Yan Z, Wang S, Hu F, Yang J., Free PMC Article | 03/19/2022 |
| LncRNA RHPN1-AS1 promotes the progression of nasopharyngeal carcinoma by targeting CELF2 expression. | LncRNA RHPN1-AS1 promotes the progression of nasopharyngeal carcinoma by targeting CELF2 expression.
Zhao Y, Zhou H, Dong W. | 12/25/2021 |
| Genome-wide association analysis of cognitive function in Danish long-lived individuals. | Genome-wide association analysis of cognitive function in Danish long-lived individuals.
Nygaard M, Dowsett J, McGue M, Christensen K, Christiansen L, Tan Q, Mengel-From J., Free PMC Article | 11/22/2021 |
| LncRNA-SNHG16 promotes proliferation and migration of acute myeloid leukemia cells via PTEN/PI3K/AKT axis through suppressing CELF2 protein. | LncRNA-SNHG16 promotes proliferation and migration of acute myeloid leukemia cells via PTEN/PI3K/AKT axis through suppressing CELF2 protein.
Shi M, Yang R, Lin J, Wei QI, Chen L, Gong W, Li Y, Guo X. | 10/16/2021 |
| STYXL1 promotes malignant progression of hepatocellular carcinoma via downregulating CELF2 through the PI3K/Akt pathway. | STYXL1 promotes malignant progression of hepatocellular carcinoma via downregulating CELF2 through the PI3K/Akt pathway.
Wu JZ, Jiang N, Lin JM, Liu X. | 03/20/2021 |
| RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery. | RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery.
Chatrikhi R, Mallory MJ, Gazzara MR, Agosto LM, Zhu WS, Litterman AJ, Ansel KM, Lynch KW., Free PMC Article | 09/19/2020 |
| CELF2 suppresses non-small cell lung carcinoma growth by inhibiting the PREX2-PTEN interaction. | CELF2 suppresses non-small cell lung carcinoma growth by inhibiting the PREX2-PTEN interaction.
Yeung YT, Fan S, Lu B, Yin S, Yang S, Nie W, Wang M, Zhou L, Li T, Li X, Bode AM, Dong Z., Free PMC Article | 08/22/2020 |
| CELF2 hypermethylation is associated with breast cancer. | Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer.
Piqué L, Martinez de Paz A, Piñeyro D, Martínez-Cardús A, Castro de Moura M, Llinàs-Arias P, Setien F, Gomez-Miragaya J, Gonzalez-Suarez E, Sigurdsson S, Jonasson JG, Villanueva A, Vidal A, Davalos V, Esteller M. | 03/7/2020 |
| These studies elucidate an unrecognized role for CELF2 in inducing autophagy and potentiating the effects of radiotherapy in colorectal cancer. | Pleotropic role of RNA binding protein CELF2 in autophagy induction.
New J, Subramaniam D, Ramalingam S, Enders J, Sayed AAA, Ponnurangam S, Standing D, Ramamoorthy P, O'Neil M, Dixon DA, Saha S, Umar S, Gunewardena S, Jensen RA, Thomas SM, Anant S., Free PMC Article | 11/9/2019 |
| Overexpression of CELF2 could reverse miR-615-3p's oncogenic functions. | miR-615-3p promotes proliferation and migration and inhibits apoptosis through its potential target CELF2 in gastric cancer.
Wang J, Liu L, Sun Y, Xue Y, Qu J, Pan S, Li H, Qu H, Wang J, Zhang J. | 09/15/2018 |
| CUG-BP2 binds to AU-rich motifs found in the COX-2 mRNA 3'-UTR. | Aromatic side-chain conformational switch on the surface of the RNA Recognition Motif enables RNA discrimination.
Diarra Dit Konté N, Krepl M, Damberger FF, Ripin N, Duss O, Šponer J, Allain FH., Free PMC Article | 01/20/2018 |
| Study provides evidence for a generalized position- dependent activity of CELF2 in splicing that can be used to predict its consequence on alternative splicing in a cell-type independent manner. | Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells.
Ajith S, Gazzara MR, Cole BS, Shankarling G, Martinez NM, Mallory MJ, Lynch KW., Free PMC Article | 10/14/2017 |
| These data suggest an interplay between CELF2 and hnRNP C as the mechanistic basis for activation-dependent alternative splicing of TRAF3 exon 8. | Activation-Dependent TRAF3 Exon 8 Alternative Splicing Is Controlled by CELF2 and hnRNP C Binding to an Upstream Intronic Element.
Schultz AS, Preussner M, Bunse M, Karni R, Heyd F., Free PMC Article | 07/1/2017 |
| Haplotype-dependent allele-specific methylation of CELF2 gene is associated with neurological disorders. | Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation.
Do C, Lang CF, Lin J, Darbary H, Krupska I, Gaba A, Petukhova L, Vonsattel JP, Gallagher MP, Goland RS, Clynes RA, Dwork A, Kral JG, Monk C, Christiano AM, Tycko B., Free PMC Article | 05/20/2017 |
| CUGBP2 expression at the messenger RNA (mRNA) level was 2.2-fold lower and could be associated with high chemoresistance and early dissemination of pancreatic cancer. | Upregulation of cugbp2 increases response of pancreatic cancer cells to chemotherapy.
Jakstaite A, Maziukiene A, Silkuniene G, Kmieliute K, Dauksa A, Paskauskas S, Gulbinas A, Dambrauskas Z. | 01/14/2017 |
| the genetic variant rs3740194 in CELF2 gene might be a valuable predictor for NPC prognosis | Association of CELF2 polymorphism and the prognosis of nasopharyngeal carcinoma in southern Chinese population.
Guo YM, Sun MX, Li J, Liu TT, Huang HZ, Chen JR, Liu WS, Feng QS, Chen LZ, Bei JX, Zeng YX., Free PMC Article | 08/20/2016 |
| Data show miR95 expression level positively related to glioma grade and its downregulation affects proliferation, invasion and apoptosis by targeting CELF2. MiR95 is identified as a putative therapeutic target and CELF2 as a potential tumor suppressor. | Downregulation of miR-95-3p inhibits proliferation, and invasion promoting apoptosis of glioma cells by targeting CELF2.
Fan B, Jiao BH, Fan FS, Lu SK, Song J, Guo CY, Yang JK, Yang L. | 05/21/2016 |
| a widespread role for the JNK-CELF2 axis in controlling splicing during T-cell activation, including a specific role in propagating JNK signaling. | Widespread JNK-dependent alternative splicing induces a positive feedback loop through CELF2-mediated regulation of MKK7 during T-cell activation.
Martinez NM, Agosto L, Qiu J, Mallory MJ, Gazzara MR, Barash Y, Fu XD, Lynch KW., Free PMC Article | 01/16/2016 |