Impact of the Multiple Sclerosis-Associated Genetic Variant CD226 Gly307Ser on Human CD8 T-Cell Functions.
Morandi E, Adoue V, Bernard I, Friebel E, Nunez N, Aubert Y, Masson F, Dejean AS, Becher B, Astier A, Martinet L, Saoudi A., Free PMC Article

Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition.
Baker FL, Smith KA, Mylabathula PL, Zúñiga TM, Diak DM, Batatinha H, Niemiro GM, Seckeler MD, Pedlar CR, O'Connor DP, Colombo J, Katsanis E, Simpson RJ., Free PMC Article

Essential role of CD155 glycosylation in functional binding to DNAM-1 on natural killer cells.
Tahara S, Okumura G, Matsuo T, Shibuya A, Shibuya K.

Increased levels of circulating soluble CD226 in multiple sclerosis.
Kari S, Bucciarelli F, Angles T, Oster AC, Cauboue P, Laviolette K, Mougenot M, Morandi E, Bernard I, Pignolet B, Bost C, Thomas J, Nogueira L, Saoudi A, Liblau R, Astier AL.

[Expression of CD226 in the small intestinal group 3 innate lymphoid cells (ILC3) in mice].
Yang L, Ma J, Liu Y, Wang T, Wang Y, Zhuang R, Zhang Z.

CD155 and Its Receptors as Targets for Cancer Therapy.
Paolini R, Molfetta R., Free PMC Article

TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation.
Worboys JD, Vowell KN, Hare RK, Ambrose AR, Bertuzzi M, Conner MA, Patel FP, Zammit WH, Gali-Moya J, Hazime KS, Jones KL, Rey C, Jonjic S, Rovis TL, Tannahill GM, Cruz De Matos GDS, Waight JD, Davis DM., Free PMC Article

Upregulation of the CD155-CD226 Axis Is Associated With Muscle Inflammation and Disease Severity in Idiopathic Inflammatory Myopathies.
Li W, Deng C, Yang H, Tian X, Chen L, Liu Q, Gao C, Lu X, Wang G, Peng Q., Free PMC Article

Upregulation of CD226 on subsets of T cells and NK cells is associated with upregulated adhesion molecules and cytotoxic factors in patients with tuberculosis.
Qin Y, Chen L, Fei Q, Shao X, Lv W, Yang J, Xu F, Shi J.

Decrease in CD226 expression on CD4(+) T cells in patients with endometriosis.
Li C, Zhou J, Shao J, Yuan L, Cheng Q, Wang L, Duan Z.

CD226 identifies functional CD8(+)T cells in the tumor microenvironment and predicts a better outcome for human gastric cancer.
Huang H, Huang Z, Ge J, Yang J, Chen J, Xu B, Wu S, Zheng X, Chen L, Zhang X, Jiang J., Free PMC Article

NKG2D engagement on human NK cells leads to DNAM-1 hypo-responsiveness through different converging mechanisms.
Milito ND, Zingoni A, Stabile H, Soriani A, Capuano C, Cippitelli M, Gismondi A, Santoni A, Paolini R, Molfetta R.

The CD226/TIGIT axis is involved in T cell hypo-responsiveness appearance in long-term kidney transplant recipients.
Del Bello A, Gouin A, Chaubet C, Kamar N, Treiner E., Free PMC Article

CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells.
Yasutomi M, Christiaansen AF, Imai N, Martin-Orozco N, Forst CV, Chen G, Ueno H., Free PMC Article

DNAM-1 versus TIGIT: competitive roles in tumor immunity and inflammatory responses.
Shibuya A, Shibuya K.

Immune checkpoint molecule TIGIT manipulates T cell dysfunction in septic patients.
Sun Y, Ding R, Chang Y, Li J, Ma X.

Functional Competence of NK Cells via the KIR/MHC Class I Interaction Correlates with DNAM-1 Expression.
Shang QN, Yu XX, Xu ZL, Cao XH, Liu XF, Zhao XS, Chang YJ, Wang Y, Zhang XH, Xu LP, Liu KY, Huang XJ, Zhao XY.

Suppression of Th1 and Th17 Proinflammatory Cytokines and Upregulation of FOXP3 Expression by a Humanized Anti-DNAM-1 Monoclonal Antibody.
Yamashita-Kanemaru Y, Oh-Oka K, Abe F, Shibuya K, Shibuya A.

Increased Proportion of CD226(+) B Cells Is Associated With the Disease Activity and Prognosis of Systemic Lupus Erythematosus.
Nakano M, Ayano M, Kushimoto K, Kawano S, Higashioka K, Inokuchi S, Mitoma H, Kimoto Y, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H., Free PMC Article

Nutlin-3a Enhances Natural Killer Cell-Mediated Killing of Neuroblastoma by Restoring p53-Dependent Expression of Ligands for NKG2D and DNAM-1 Receptors.
Veneziani I, Infante P, Ferretti E, Melaiu O, Battistelli C, Lucarini V, Compagnone M, Nicoletti C, Castellano A, Petrini S, Ognibene M, Pezzolo A, Di Marcotullio L, Bei R, Moretta L, Pistoia V, Fruci D, Barnaba V, Locatelli F, Cifaldi L.

DNAM-1/CD226 is functionally expressed on acute myeloid leukemia (AML) cells and is associated with favorable prognosis.
Chashchina A, Märklin M, Hinterleitner C, Salih HR, Heitmann JS, Klimovich B., Free PMC Article

IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma.
Chauvin JM, Ka M, Pagliano O, Menna C, Ding Q, DeBlasio R, Sanders C, Hou J, Li XY, Ferrone S, Davar D, Kirkwood JM, Johnston RJ, Korman AJ, Smyth MJ, Zarour HM., Free PMC Article

CD226 deficiency promotes glutaminolysis and alleviates mitochondria damage in vascular endothelial cells under hemorrhagic shock.
Zhou S, Xie J, Yu C, Feng Z, Cheng K, Ma J, Wang Y, Duan C, Zhang Y, Jin B, Yin W, Zhuang R.

Association of elevated serum soluble CD226 levels with the disease activity and flares of systemic lupus erythematosus.
Nakano M, Ayano M, Kushimoto K, Kawano S, Higashioka K, Inokuchi S, Mitoma H, Kimoto Y, Akahoshi M, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H., Free PMC Article

Alteration of CD226/TIGIT immune checkpoint on T cells in the pathogenesis of primary Sjögren's syndrome.
Deng C, Chen Y, Li W, Peng L, Luo X, Peng Y, Zhao L, Wu Q, Zhang W, Zhang X, Fei Y.